Search Results - "Stafford, Benjamin K."
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Contactin-4 Mediates Axon-Target Specificity and Functional Development of the Accessory Optic System
Published in Neuron (Cambridge, Mass.) (20-05-2015)“…The mammalian eye-to-brain pathway includes more than 20 parallel circuits, each consisting of precise long-range connections between specific sets of retinal…”
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2
Neural activity promotes long-distance, target-specific regeneration of adult retinal axons
Published in Nature neuroscience (01-08-2016)“…A combination of increased neural activity, induced by visual stimulation or using chemogenetics, and increasing mTOR signaling promotes retinal ganglion cell…”
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3
Neurotoxic Reactive Astrocytes Drive Neuronal Death after Retinal Injury
Published in Cell reports (Cambridge) (23-06-2020)“…Glaucoma is a neurodegenerative disease that features the death of retinal ganglion cells (RGCs) in the retina, often as a result of prolonged increases in…”
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4
Parallel pathways carrying direction-and orientation-selective retinal signals to layer 4 of the mouse visual cortex
Published in Cell reports (Cambridge) (26-03-2024)“…Parallel visual pathways from the retina to the primary visual cortex (V1) via the lateral geniculate nucleus are common to many mammalian species, including…”
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Molecular Fingerprinting of On-Off Direction-Selective Retinal Ganglion Cells Across Species and Relevance to Primate Visual Circuits
Published in The Journal of neuroscience (02-01-2019)“…The ability to detect moving objects is an ethologically salient function. Direction-selective neurons have been identified in the retina, thalamus, and cortex…”
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6
Developmental changes in NMDA receptor subunit composition at ON and OFF bipolar cell synapses onto direction-selective retinal ganglion cells
Published in The Journal of neuroscience (29-01-2014)“…In the developing mouse retina, spontaneous and light-driven activity shapes bipolar→ganglion cell glutamatergic synapse formation, beginning around the time…”
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Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways
Published in Nature (London) (19-12-2013)“…To achieve its precise neural connectivity, the developing mammalian nervous system undergoes extensive activity-dependent synapse remodelling. Recently,…”
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8
Signal Integration in Thalamus: Labeled Lines Go Cross-Eyed and Blurry
Published in Neuron (Cambridge, Mass.) (22-02-2017)“…The brain uses sensory information from the periphery to create percepts. In this issue of Neuron, Rompani et al. (2017) show that visual signals are combined…”
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Contributions of Retinal Ganglion Cells to Subcortical Visual Processing and Behaviors
Published in Annual review of vision science (24-11-2015)“…Every aspect of visual perception and behavior is built from the neural activity of retinal ganglion cells (RGCs), the output neurons of the eye. Here, we…”
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10
Neurotoxic Reactive Astrocytes Drive Neuronal Death after Retinal Injury
Published in Cell reports (Cambridge) (25-06-2024)Get full text
Journal Article -
11
NMDA Receptor Contributions to Visual Contrast Coding
Published in Neuron (Cambridge, Mass.) (29-07-2010)“…In the retina, it is not well understood how visual processing depends on AMPA- and NMDA-type glutamate receptors. Here we investigated how these receptors…”
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NMDA and AMPA receptors contribute similarly to temporal processing in mammalian retinal ganglion cells
Published in The Journal of physiology (15-11-2014)“…Key points In most areas of the brain, NMDA‐type glutamate receptors (NMDARs) exhibit slower kinetics than do AMPA‐type receptors (AMPARs). Most retinal…”
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Protein Interacting with C-Kinase 1/Protein Kinase Cα-Mediated Endocytosis Converts Netrin-1-Mediated Repulsion to Attraction
Published in The Journal of neuroscience (22-03-2006)“…In vertebrates, the receptor families deleted in colorectal cancer (DCC) and UNC5 mediate responses to the bifunctional guidance cue netrin-1. DCC mediates…”
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14
Neurotoxic reactive astrocytes drive neuronal death following retinal injury
Published in Cell reports (Cambridge) (23-06-2020)“…Glaucoma is a neurodegenerative disease that features the death of retinal ganglion cells (RGCs) in the retina, often as a result of prolonged increases in…”
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Journal Article -
15
Functional characterization of the developing and adult mouse retina
Published 01-01-2009“…The retina is the source of all visual input into the brain and by understanding how the retina converts photons of light into patterns of electrical activity…”
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Dissertation -
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Functional characterization of the developing and adult mouse retina
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Dissertation -
17
Protein interacting with C-kinase 1/protein kinase Calpha-mediated endocytosis converts netrin-1-mediated repulsion to attraction
Published in The Journal of neuroscience (22-03-2006)“…In vertebrates, the receptor families deleted in colorectal cancer (DCC) and UNC5 mediate responses to the bifunctional guidance cue netrin-1. DCC mediates…”
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Journal Article -
18
Protein Interacting with C-Kinase 1/Protein Kinase C{alpha}-Mediated Endocytosis Converts Netrin-1-Mediated Repulsion to Attraction
Published in The Journal of neuroscience (22-03-2006)Get full text
Journal Article