Search Results - "Staempfli, Andreas"
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Longitudinal Analysis of Multiple Neurotransmitter Metabolites in Cerebrospinal Fluid in Early Parkinson's Disease
Published in Movement disorders (01-08-2021)“…ABSTRACT Background Cerebrospinal fluid (CSF) levels of monoamine metabolites may represent biomarkers of Parkinson's disease (PD). Objective The aim of this…”
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Differential regulation of bile acid and cholesterol metabolism by the farnesoid X receptor in Ldlr−/− mice versus hamsters[S]
Published in Journal of lipid research (01-05-2013)“…Modulating bile acid synthesis has long been considered a good strategy by which to improve cholesterol homeostasis in humans. The farnesoid X receptor (FXR),…”
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How Female Mice Attract Males: A Urinary Volatile Amine Activates a Trace Amine-Associated Receptor That Induces Male Sexual Interest
Published in Frontiers in pharmacology (15-08-2018)“…Individuals of many species rely on odors to communicate, find breeding partners, locate resources and sense dangers. In vertebrates, odorants are detected by…”
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Isoleucine Biosynthesis in Leptospira interrogans Serotype lai Strain 56601 Proceeds via a Threonine-Independent Pathway
Published in Journal of Bacteriology (01-08-2004)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Effect of Dalcetrapib and Torcetrapib on Noncholesterol Markers of Cholesterol Homeostasis in the Hamster
Published in Journal of clinical lipidology (01-05-2011)Get full text
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6
Lewy pathology in Parkinson’s disease consists of crowded organelles and lipid membranes
Published in Nature neuroscience (01-07-2019)“…Parkinson’s disease, the most common age-related movement disorder, is a progressive neurodegenerative disease with unclear etiology. Key neuropathological…”
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Degradation of polysorbates 20 and 80: studies on thermal autoxidation and hydrolysis
Published in Journal of pharmaceutical sciences (01-02-2011)“…The purpose of this work was to study the mechanistic pathways of degradation of polysorbates (PS) 20 and PS80 in parenteral formulations. The fate of PS in…”
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Ring opening of cyclic sulfamidates with bromophenyl metal reagents: complementarity of sulfamidates and aziridines
Published in Tetrahedron letters (12-10-2011)“…Bromophenyl magnesium reagents generated via a Knochel type magnesium–halogen exchange of aryl iodides undergo regioselective ring opening of cyclic primary…”
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Effect of Compounds Affecting ABCA1 Expression and CETP Activity on the HDL Pathway Involved in Intestinal Absorption of Lutein and Zeaxanthin
Published in Lipids (01-12-2014)“…The antioxidant xanthophylls lutein and zeaxanthin are absorbed from the diet in a process involving lipoprotein formation. Selective mechanisms exist for…”
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Gas-phase dissociation mechanisms of dilithiated disaccharides: tandem mass spectrometry and semiempirical calculations
Published in Journal of organic chemistry (01-06-1992)Get full text
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Modeling the Effects of Severe Metabolic Disease by Genome Editing of hPSC-Derived Endothelial Cells Reveals an Inflammatory Phenotype
Published in International journal of molecular sciences (09-12-2019)“…The kinase AKT2 (PKB) is an important mediator of insulin signaling, for which loss-of-function knockout (KO) mutants lead to early onset diabetes mellitus,…”
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Effect of dalcetrapib, a CETP modulator, on non-cholesterol sterol markers of cholesterol homeostasis in healthy subjects
Published in Atherosclerosis (01-12-2011)“…Abstract Objective Subjects with high HDL-C show elevated plasma markers of cholesterol absorption and reduced markers of cholesterol synthesis. We evaluated…”
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Abstract LB-085: RG70099: A novel, highly potent dual IDO1/TDO inhibitor to reverse metabolic suppression of immune cells in the tumor micro-environment
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…Abstract IDO1/TDO* mediate substantial immunosuppressive effects through the metabolism of tryptophan (Trp) to kynurenine (Kyn). The consequent decrease in Trp…”
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Abstract LB-085: RG70099: A novel, highly potent dual IDO1TDO inhibitor to reverse metabolic suppression of immune cells in the tumor micro-environment
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…IDO1TDO mediate substantial immunosuppressive effects through the metabolism of tryptophan (Trp) to kynurenine (Kyn). The consequent decrease in Trp suppresses…”
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Synthesis of Multiply-Labeled [15N3,13C1]-8-Oxo-Substituted Purine Bases and Their Corresponding 2'-Deoxynucleosides
Published in Chemical research in toxicology (01-11-1994)“…Stable isotope-labeled analogues of oxidatively modified purine bases are required as internal standards for accurate quantitation of free radical induced…”
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Effect of dalcetrapib on non-cholesterol markers of cholesterol homeostasis in healthy subjects and a hamster model
Published in Atherosclerosis (01-10-2011)Get full text
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Identification and structure of a family of syringolin variants : Unusual cyclic peptides from Pseudomonas syringae pv. syringae that elicit defense responses in rice
Published in Microbiological research (01-05-1999)“…Pseudomonas syringae pv. syringae is recognized by the non-host plant Oryza sativa which reacts with defense responses leading to induced resistance towards…”
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Mechanism of gas-phase aldose-ketose isomerization: a study using tandem mass spectrometry and theoretical calculations
Published in Journal of the American Society for Mass Spectrometry (01-12-1993)“…Fast-atom bombardment tandem mass spectrometry and the semiempirical molecular orbital method were used to investigate the mechanism of gas-phase aldose-ketose…”
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