Search Results - "Staedel, Cathy"
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Verteporfin targeting YAP1/TAZ‐TEAD transcriptional activity inhibits the tumorigenic properties of gastric cancer stem cells
Published in International journal of cancer (15-04-2020)“…Gastric carcinomas (GC) are heterogeneous tumors, composed of a subpopulation of cluster of differentiation‐44 (CD44)+ tumorigenic and chemoresistant cancer…”
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2
CD44v3 is a marker of invasive cancer stem cells driving metastasis in gastric carcinoma
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01-03-2023)“…Background Cancer stem cells (CSCs) are at the origin of tumour initiation and progression in gastric adenocarcinoma (GC). However, markers of…”
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3
Helicobacter pylori initiates a mesenchymal transition through ZEB1 in gastric epithelial cells
Published in PloS one (02-04-2013)“…Chronic Helicobacter pylori infection provokes an inflammation of the gastric mucosa, at high risk for ulcer and cancer development. The most virulent strains…”
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4
Modulation of oncogenic miRNA biogenesis using functionalized polyamines
Published in Scientific reports (26-01-2018)“…MicroRNAs are key factors in the regulation of gene expression and their deregulation has been directly linked to various pathologies such as cancer. The use…”
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5
Nucleoside-Lipid-Based Nanocarriers for Sorafenib Delivery
Published in Nanoscale research letters (11-01-2018)“…Although the application of sorafenib, a small inhibitor of tyrosine protein kinases, to cancer treatments remains a worldwide option in chemotherapy, novel…”
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6
Oncogenic MicroRNAs Biogenesis as a Drug Target: Structure-Activity Relationship Studies on New Aminoglycoside Conjugates
Published in Chemistry : a European journal (04-04-2016)“…MicroRNAs (miRNAs) are a recently discovered category of small RNA molecules that regulate gene expression at the post‐transcriptional level. Accumulating…”
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7
Deregulation of miRNA in Helicobacter pylori -Induced Gastric MALT Lymphoma: From Mice to Human
Published in Journal of clinical medicine (13-06-2019)“…Gastric MALT lymphoma (GML) is directly caused by infection but occurs only in a small number of infected subjects. Mechanisms underlying the initiation and…”
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8
TAZ Controls Helicobacter pylori -Induced Epithelial-Mesenchymal Transition and Cancer Stem Cell-Like Invasive and Tumorigenic Properties
Published in Cells (Basel, Switzerland) (13-06-2020)“…infection, the main risk factor for gastric cancer (GC), leads to an epithelial-mesenchymal transition (EMT) of gastric epithelium contributing to gastric…”
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9
Cellular Internalization of Water-Soluble Helical Aromatic Amide Foldamers
Published in Chembiochem : a European journal of chemical biology (16-08-2010)“…The intracellular transport of drugs and therapeutics represents one of the most exciting and challenging areas at the interface of chemistry, biology, and…”
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10
Deregulation of MicroRNAs in Gastric Lymphomagenesis Induced in the d3Tx Mouse Model of Helicobacter pylori Infection
Published in Frontiers in cellular and infection microbiology (16-05-2017)“…infection is considered as an excellent model of chronic inflammation-induced tumor development. Our project focuses on gastric MALT lymphoma (GML) related to…”
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11
αv integrins regulate cell proliferation through integrin-linked kinase (ILK) in ovarian cancer cells
Published in Oncogene (20-03-2003)“…Integrins regulate both adhesion and signaling processes involved in proliferation and survival. αvβ3 and αvβ5 integrins have been shown to mediate cell…”
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12
Resistance of colon cancer cells to long‐term 5‐fluorouracil exposure is correlated to the relative level of Bcl‐2 and Bcl‐XL in addition to Bax and p53 status
Published in International journal of cancer (01-04-2002)“…Defects in apoptosis have been implicated in chemoresistance of colon cancer cells. We report here the ability to resist to 5‐fluorouracil‐induced apoptosis of…”
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13
MicroRNAs and bacterial infection
Published in Cellular microbiology (01-09-2013)“…Summary MicroRNAs, small non‐coding RNAs expressed by eukaryotic cells, play pivotal roles in shaping cell differentiation and organism development…”
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14
Inhibition of Gastric Tumor Cell Growth Using Seed-targeting LNA as Specific, Long-lasting MicroRNA Inhibitors
Published in Molecular therapy. Nucleic acids (01-07-2015)“…MicroRNAs regulate eukaryotic gene expression upon pairing onto target mRNAs. This targeting is influenced by the complementarity between the microRNA “seed”…”
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15
Inhibition of Hepatitis C Virus (HCV) RNA Polymerase by DNA Aptamers: Mechanism of Inhibition of In Vitro RNA Synthesis and Effect on HCV-Infected Cells
Published in Antimicrobial Agents and Chemotherapy (01-06-2008)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Development and Biological Assessment of Fully Water-Soluble Helical Aromatic Amide Foldamers
Published in Angewandte Chemie International Edition (01-01-2007)Get full text
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17
Altered adhesion properties and alpha v integrin expression in a cisplatin‐resistant human ovarian carcinoma cell line
Published in International journal of cancer (10-01-2002)“…In order to elucidate the mechanisms underlying the development of chemoresistance in ovarian cancer, we have previously established the IGROV1‐R10…”
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18
Targeting the Production of Oncogenic MicroRNAs with Multimodal Synthetic Small Molecules
Published in ACS chemical biology (21-03-2014)“…MicroRNAs (miRNAs) are a recently discovered category of small RNA molecules that regulate gene expression at the post-transcriptional level. Accumulating…”
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19
Glycosyl-nucleoside-lipid based supramolecular assembly as a nanostructured material with nucleic acid delivery capabilities
Published in Chemical communications (Cambridge, England) (01-01-2009)“…A glycosyl-nucleoside-lipid self-assembles to give highly organized structures such as fibers and nanotubes, which can stabilize hydrogels; carbohydrate…”
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Rapid decay of engulfed extracellular miRNA by XRN1 exonuclease promotes transient epithelial-mesenchymal transition
Published in Nucleic acids research (20-04-2017)“…Extracellular vesicles (EVs) have been shown to play an important role in intercellular communication as carriers of DNA, RNA and proteins. While the…”
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