Search Results - "Stadtmann, Anika"

GDF-15 is an inhibitor of leukocyte integrin activation required for survival after myocardial infarction in mice by Kempf, Tibor, Zarbock, Alexander, Widera, Christian, Butz, Stefan, Stadtmann, Anika, Rossaint, Jan, Bolomini-Vittori, Matteo, Korf-Klingebiel, Mortimer, Napp, L Christian, Hansen, Birte, Kanwischer, Anna, Bavendiek, Udo, Beutel, Gernot, Hapke, Martin, Sauer, Martin G, Laudanna, Carlo, Hogg, Nancy, Vestweber, Dietmar, Wollert, Kai C

“…Inflammatory cell recruitment to injured tissues is needed for repair, but an excessive inflammatory response can exacerbate injury. Tibor Kempf et al . now…”
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Endothelial Basement Membrane Laminin 511 Contributes to Endothelial Junctional Tightness and Thereby Inhibits Leukocyte Transmigration by Song, Jian, Zhang, Xueli, Buscher, Konrad, Wang, Ying, Wang, Huiyu, Di Russo, Jacopo, Li, Lixia, Lütke-Enking, Stefan, Zarbock, Alexander, Stadtmann, Anika, Striewski, Paul, Wirth, Benedikt, Kuzmanov, Ivan, Wiendl, Heinz, Schulte, Dörte, Vestweber, Dietmar, Sorokin, Lydia

“…Endothelial basement membranes constitute barriers to extravasating leukocytes during inflammation, a process where laminin isoforms define sites of leukocyte…”
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6% Hydroxyethyl starch (HES 130/0.4) diminishes glycocalyx degradation and decreases vascular permeability during systemic and pulmonary inflammation in mice by Margraf, Andreas, Herter, Jan M, Kühne, Katharina, Stadtmann, Anika, Ermert, Thomas, Wenk, Manuel, Meersch, Melanie, Van Aken, Hugo, Zarbock, Alexander, Rossaint, Jan

“…Increased vascular permeability is a pathophysiological hallmark of sepsis and results in increased transcapillary leakage of plasma fluid, hypovolemia, and…”
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Crucial role of SLP-76 and ADAP for neutrophil recruitment in mouse kidney ischemia-reperfusion injury by Block, Helena, Herter, Jan M, Rossaint, Jan, Stadtmann, Anika, Kliche, Stefanie, Lowell, Clifford A, Zarbock, Alexander

“…Neutrophils trigger inflammation-induced acute kidney injury (AKI), a frequent and potentially lethal occurrence in humans. Molecular mechanisms underlying…”
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Rap1a activation by CalDAG‐GEFI and p38 MAPK is involved in E‐selectin‐dependent slow leukocyte rolling by Stadtmann, Anika, Brinkhaus, Laura, Mueller, Helena, Rossaint, Jan, Bolomini‐Vittori, Matteo, Bergmeier, Wolfgang, Van Aken, Hugo, Wagner, Denisa D., Laudanna, Carlo, Ley, Klaus, Zarbock, Alexander

“…Rolling leukocytes are exposed to different adhesion molecules and chemokines. Neutrophils rolling on E‐selectin induce integrin αLβ2‐mediated slow rolling on…”
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The role for decorin in delayed-type hypersensitivity by Seidler, Daniela G, Mohamed, Negia A, Bocian, Carla, Stadtmann, Anika, Hermann, Sven, Schäfers, Klaus, Schäfers, Michael, Iozzo, Renato V, Zarbock, Alexander, Götte, Martin

“…Decorin, a small leucine-rich proteoglycan, regulates extracellular matrix organization, growth factor-mediated signaling, and cell growth. Because decorin may…”
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STIMulation of signaling in neutrophils by Stadtmann, Anika, Zarbock, Alexander

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The role of kindlin in neutrophil recruitment to inflammatory sites by Stadtmann, Anika, Zarbock, Alexander

“…PURPOSE OF REVIEWSince the discovery of the lack of kindlin-3 expression as the reason for the immunopathology leukocyte adhesion deficiency III syndrome, the…”
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CXCR2: From Bench to Bedside by Stadtmann, Anika, Zarbock, Alexander

“…Leukocyte recruitment to sites of infection or tissue damage plays a crucial role for the innate immune response. Chemokine-dependent signaling in immune cells…”
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Leukocyte extravasation and vascular permeability are each controlled in vivo by different tyrosine residues of VE-cadherin by Wessel, Florian, Winderlich, Mark, Holm, Maren, Frye, Maike, Rivera-Galdos, Ronmy, Vockel, Matthias, Linnepe, Ruth, Ipe, Ute, Stadtmann, Anika, Zarbock, Alexander, Nottebaum, Astrid F, Vestweber, Dietmar

“…Tyrosine phosphorylation of VE-cadherin affects endothelial junction integrity. Vestweber and colleagues show that two different tyrosine residues distinctly…”
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Tyrosine kinase Btk regulates E-selectin–mediated integrin activation and neutrophil recruitment by controlling phospholipase C (PLC) γ2 and PI3Kγ pathways by Mueller, Helena, Stadtmann, Anika, Van Aken, Hugo, Hirsch, Emilio, Wang, Demin, Ley, Klaus, Zarbock, Alexander

“…Selectins mediate leukocyte rolling, trigger β2-integrin activation, and promote leukocyte recruitment into inflamed tissue. E-selectin binding to P-selectin…”
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The PSGL-1-L-selectin signaling complex regulates neutrophil adhesion under flow by Stadtmann, Anika, Germena, Giulia, Block, Helena, Boras, Mark, Rossaint, Jan, Sundd, Prithu, Lefort, Craig, Fisher, Charles I, Buscher, Konrad, Gelschefarth, Bernadette, Urzainqui, Ana, Gerke, Volker, Ley, Klaus, Zarbock, Alexander

“…Neutrophils are recruited from the blood to sites of inflammation, where they contribute to immune defense but may also cause tissue damage. During…”
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Cross-Talk between Shp1 and PIPKIγ Controls Leukocyte Recruitment by Stadtmann, Anika, Block, Helena, Volmering, Stephanie, Abram, Clare, Sohlbach, Charlotte, Boras, Mark, Lowell, Clifford A, Zarbock, Alexander

“…Neutrophil recruitment to the site of inflammation plays a pivotal role in host defense. However, overwhelming activation and accumulation of neutrophils in…”
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Coordinated and unique functions of the E-selectin ligand ESL-1 during inflammatory and hematopoietic recruitment in mice by Sreeramkumar, Vinatha, Leiva, Magdalena, Stadtmann, Anika, Pitaval, Christophe, Ortega-Rodríguez, Inés, Wild, Martin K., Lee, Brendan, Zarbock, Alexander, Hidalgo, Andrés

“…Beyond its well-established roles in mediating leukocyte rolling, E-selectin is emerging as a multifunctional receptor capable of inducing integrin activation…”
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Adam17-dependent shedding limits early neutrophil influx but does not alter early monocyte recruitment to inflammatory sites by Tang, Jingjing, Zarbock, Alexander, Gomez, Ivan, Wilson, Carole L., Lefort, Craig T., Stadtmann, Anika, Bell, Bridgit, Huang, Li-Chuan, Ley, Klaus, Raines, Elaine W.

“…TNF-α-converting enzyme (TACE, herein denoted as Adam17) proteolytically sheds several cell-surface inflammatory proteins, but the physiologic importance of…”
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Crosstalk between Shp1 and PIPKIγ controls leukocyte recruitment. by Stadtmann, Anika, Block, Helena, Volmering, Stephanie, Abram, Clare, Sohlbach, Charlotte, Boras, Mark, Lowell, Clifford A., Zarbock, Alexander

“…Neutrophil recruitment to site of inflammation plays a pivotal role in host defense. However, an overwhelming activation and accumulation of neutrophils in the…”
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Gnb isoforms control a signaling pathway comprising Rac1, Plcβ2, and Plcβ3 leading to LFA-1 activation and neutrophil arrest in vivo by Block, Helena, Stadtmann, Anika, Riad, Daniel, Rossaint, Jan, Sohlbach, Charlotte, Germena, Giulia, Wu, Dianqing, Simon, Scott I., Ley, Klaus, Zarbock, Alexander

“…Chemokines are required for leukocyte recruitment and appropriate host defense and act through G protein-coupled receptors (GPCRs), which induce downstream…”
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Inhibition of platelet‐induced NETosis via disruption of CXCL4/CCL5‐heteromerformation ameliorates organ damage after in ventilator‐induced lung injury (146.3) by Herter, Jan, Rossaint, Jan, Soehnlein, Oliver, Weber, Christian, Stadtmann, Anika, Block, Helena, Aken, Hugo, Zarbock, Alexander

“…Platelet leukocyte interactions are a hallmark of inflammation. We here report that platelet induced formation of neutrophils extracellular traps (NETs) is…”
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Neutrophil slow rolling and intravascular crawling is dependent on the guanine‐exchange factor P‐Rex1 by Herter, Jan Michael, Rossiant, Jan, Block, Helena, Stadtmann, Anika, Welch, Heidi, Zarbock, Alexander

“…Abstract only Integrin activation is a hallmark for the function of leukocytes and concise trafficking. Here, we investigated the role of P‐Rex1, a…”
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Selectins and integrins in ischemia‐reperfusion and sepsis induced murine acute kidney injury by Herter, Jan Michael, Block, Helena, Rossiant, Jan, Stadtmann, Anika, Zarbock, Alexander

“…Abstract only Ischemia‐reperfusion induced kidney injury has been the most frequently used model for acute kidney injury (AKI) in mice. However, sepsis is the…”
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