Search Results - "Stabler, Thomas V"

Uric acid is a danger signal of increasing risk for osteoarthritis through inflammasome activation by Denoble, Anna E, Huffman, Kim M, Stabler, Thomas V, Kelly, Susan J, Hershfield, Michael S, McDaniel, Gary E, Coleman, R. Edward, Kraus, Virginia B

“…Uric acid (UA) is known to activate the NLRP3 (Nacht, leucine-rich repeat and pyrin domain containing protein 3) inflammasome. When activated, the NLRP3 (also…”
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Isolation of Functional Human Endothelial Cells from Small Volumes of Umbilical Cord Blood by Kang, Sa Do, Carlon, Tim A., Jantzen, Alexandra E., Lin, Fu-Hsiung, Ley, Melissa M., Allen, Jason D., Stabler, Thomas V., Haley, N. Rebecca, Truskey, George A., Achneck, Hardean E.

“…Endothelial cells (ECs) isolated from endothelial progenitor cells in blood have great potential as a therapeutic tool to promote vasculogenesis and…”
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Chondroitin Sulfate Inhibits Monocyte Chemoattractant Protein-1 Release From 3T3-L1 Adipocytes: A New Treatment Opportunity for Obesity-Related Inflammation? by Stabler, Thomas V, Montell, Eulàlia, Vergés, Josep, Huebner, Janet L, Kraus, Virginia Byers

“…Monocyte chemoattractant protein-1 (MCP-1) overproduction from inflamed adipose tissue is a major contributor to obesity-related metabolic syndromes. 3T3-L1…”
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Synovial Fluid Profile at the Time of Anterior Cruciate Ligament Reconstruction and Its Association With Cartilage Matrix Composition 3 Years After Surgery by Amano, Keiko, Huebner, Janet L., Stabler, Thomas V., Tanaka, Matthew, McCulloch, Charles E., Lobach, Iryna, Lane, Nancy E., Kraus, Virginia B., Ma, C. Benjamin, Li, Xiaojuan

“…Background: Anterior cruciate ligament tears can lead to posttraumatic osteoarthritis. In addition to biomechanical factors, changes in biochemical profiles…”
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Amino acid racemization reveals differential protein turnover in osteoarthritic articular and meniscal cartilages by Stabler, Thomas V, Byers, Samuel S, Zura, Robert D, Kraus, Virginia Byers

“…Certain amino acids within proteins have been reported to change from the L form to the D form over time. This process is known as racemization and is most…”
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Changes in serum and synovial fluid biomarkers after acute injury (NCT00332254) by Catterall, Jonathan B, Stabler, Thomas V, Flannery, Carl R, Kraus, Virginia B

“…Acute trauma involving the anterior cruciate ligament is believed to be a major risk factor for the development of post-traumatic osteoarthritis 10 to 20 years…”
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Inflammatory Microenvironment Persists After Bone Healing in Intra-articular Ankle Fractures by Adams, Samuel B., Leimer, Elizabeth M., Setton, Lori A., Bell, Richard D., Easley, Mark E., Huebner, Janet L., Stabler, Thomas V., Kraus, Virginia B., Olson, Steven A., Nettles, Dana L.

“…Background: Post-traumatic osteoarthritis (PTOA) is responsible for the majority of cases of ankle arthritis. While acute and end-stage intra-articular…”
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Monosodium urate crystal induced macrophage inflammation is attenuated by chondroitin sulphate: pre-clinical model for gout prophylaxis? by Orlowsky, Eric W, Stabler, Thomas V, Montell, Eulàlia, Vergés, Josep, Kraus, Virginia Byers

“…Chondroitin Sulphate (CS), a natural glycosaminoglycan of the extracellular matrix, has clinical benefit in symptomatic osteoarthritis but has never been…”
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biocompatibility of titanium cardiovascular devices seeded with autologous blood-derived endothelial progenitor cells EPC-seeded antithrombotic Ti Implants by Achneck, Hardean E, Jamiolkowski, Ryan M, Jantzen, Alexandra E, Haseltine, Justin M, Lane, Whitney O, Huang, Jessica K, Galinat, Lauren J, Serpe, Michael J, Lin, Fu-Hsiung, Li, Madison, Parikh, Amar, Ma, Liqiao, Chen, Tao, Sileshi, Bantayehu, Milano, Carmelo A, Wallace, Charles S, Stabler, Thomas V, Allen, Jason D, Truskey, George A, Lawson, Jeffrey H

“…Implantable and extracorporeal cardiovascular devices are commonly made from titanium (Ti) (e.g. Ti-coated Nitinol stents and mechanical circulatory assist…”
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Protein Modification by Deamidation Indicates Variations in Joint Extracellular Matrix Turnover by Catterall, Jonathan B., Hsueh, Ming F., Stabler, Thomas V., McCudden, Christopher R., Bolognesi, Michael, Zura, Robert, Jordan, Joanne M., Renner, Jordan B., Feng, Sheng, Kraus, Virginia B.

“…As extracellular proteins age, they undergo and accumulate nonenzymatic post-translational modifications that cannot be repaired. We hypothesized that these…”
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Variation in osteoarthritis biomarkers from activity not food consumption by Gordon, Craig D., Stabler, Thomas V., Kraus, Virginia B.

“…To optimize sampling and to understand sources of variation in biomarkers for osteoarthritis (OA), we evaluated variation due to activity and food consumption…”
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Whole blood lead levels are associated with biomarkers of joint tissue metabolism in African American and white men and women: The Johnston County Osteoarthritis Project by Nelson, Amanda E., Chaudhary, Sanjay, Kraus, Virginia B., Fang, Fang, Chen, Jiu-Chiuan, Schwartz, Todd A., Shi, Xiaoyan A., Renner, Jordan B., Stabler, Thomas V., Helmick, Charles G., Caldwell, Kathleen, Robin Poole, A., Jordan, Joanne M.

“…To examine associations between biomarkers of joint tissue metabolism and whole blood lead (Pb), separately for men and women in an African American and…”
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Increased yield of endothelial cells from peripheral blood for cell therapies and tissue engineering by Jamiolkowski, Ryan M, Kang, Sa Do, Rodriguez, AnnMarie K, Haseltine, Justin M, Galinat, Lauren J, Jantzen, Alexandra E, Carlon, Tim A, Darrabie, Marcus D, Arciniegas, Antonio J, Mantilla, Jose G, Haley, N Rebecca, Noviani, Maria, Allen, Jason D, Stabler, Thomas V, Frederiksen, James W, Alzate, Oscar, Keil, Lukas G, Liu, Siyao, Lin, Fu-Hsiung, Truskey, George A, Achneck, Hardean E

“…Peripheral blood-derived endothelial cells (pBD-ECs) are an attractive tool for cell therapies and tissue engineering, but have been limited by their low…”
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The biocompatibility of titanium cardiovascular devices seeded with autologous blood-derived endothelial progenitor cells by Achneck, Hardean E, Jamiolkowski, Ryan M, Jantzen, Alexandra E, Haseltine, Justin M, Lane, Whitney O, Huang, Jessica K, Galinat, Lauren J, Serpe, Michael J, Lin, Fu-Hsiung, Li, Madison, Parikh, Amar, Ma, Liqiao, Chen, Tao, Sileshi, Bantayehu, Milano, Carmelo A, Wallace, Charles S, Stabler, Thomas V, Allen, Jason D, Truskey, George A, Lawson, Jeffrey H

“…Abstract Implantable and extracorporeal cardiovascular devices are commonly made from titanium (Ti) (e.g. Ti-coated Nitinol stents and mechanical circulatory…”
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Ascorbic acid accumulates in cartilage in vivo by Stabler, Thomas V., Kraus, Virginia B.

“…Background: Ascorbic acid plays an important role in collagen synthesis. Though ascorbic acid concentrations in many tissues and in plasma have been…”
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Dehydroascorbate transport in human chondrocytes is regulated by hypoxia and is a physiologically relevant source of ascorbic acid in the joint by McNulty, Amy L., Stabler, Thomas V., Vail, Thomas P., McDaniel, Gary E., Kraus, Virginia B.

“…Objective To evaluate the dehydroascorbate (DHA) transport mechanisms in human chondrocytes. Methods The transport of L‐14C‐DHA in human chondrocytes was…”
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Direct in vivo evidence of activated macrophages in human osteoarthritis by Kraus, V.B, McDaniel, G, Huebner, J.L, Stabler, T.V, Pieper, C.F, Shipes, S.W, Petry, N.A, Low, P.S, Shen, J, McNearney, T.A, Mitchell, P

“…Summary Objective Through binding to folate receptor-β (FR-β), the new99m Tc–EC20 (Etarfolatide) imaging technique detects activated but not resting…”
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Infrapatellar fat pad abnormalities are associated with a higher inflammatory synovial fluid cytokine profile in young adults following ACL tear by Heilmeier, U., Mamoto, K., Amano, K., Eck, B., Tanaka, M., Bullen, J.A., Schwaiger, B.J., Huebner, J.L., Stabler, T.V., Kraus, V.B., Ma, C.B., Link, T.M., Li, X.

“…To evaluate the degree of knee fat pad abnormalities after acute anterior cruciate ligament (ACL) tear via magnetic resonance fat pad scoring and to assess…”
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TSG-6 activity as a novel biomarker of progression in knee osteoarthritis by Wisniewski, H.-G, Colón, E, Liublinska, V, Karia, R.J, Stabler, T.V, Attur, M, Abramson, S.B, Band, P.A, Kraus, V.B

“…Summary Objective To establish whether there is an association between TSG-6 activity and osteoarthritis progression. Design TSG-6 activity was determined in…”
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Selenomethionine inhibits IL-1β inducible nitric oxide synthase (iNOS) and cyclooxygenase 2 (COX2) expression in primary human chondrocytes by Cheng, A.W.M, Stabler, T.V, Bolognesi, M, Kraus, V.B

“…Summary Objective Several lines of evidence show that selenium (Se) has potential protective effects in osteoarthritis (OA), however the exact mechanism is…”
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