Search Results - "Stabler, Richard"

Effects of Eimeria tenella infection on chicken caecal microbiome diversity, exploring variation associated with severity of pathology by Macdonald, Sarah E, Nolan, Matthew J, Harman, Kimberley, Boulton, Kay, Hume, David A, Tomley, Fiona M, Stabler, Richard A, Blake, Damer P

“…Eimeria species cause the intestinal disease coccidiosis, most notably in poultry. While the direct impact of coccidiosis on animal health and welfare is…”
Get full text

Subscription model for antibiotic development by Glover, Rebecca E, Manton, John, Willcocks, Sam, Stabler, Richard A

“…An unlikely answer to the global crisis in antibiotic resistance…”
Get full text

Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium by Stabler, Richard A, He, Miao, Dawson, Lisa, Martin, Melissa, Valiente, Esmeralda, Corton, Craig, Lawley, Trevor D, Sebaihia, Mohammed, Quail, Michael A, Rose, Graham, Gerding, Dale N, Gibert, Maryse, Popoff, Michel R, Parkhill, Julian, Dougan, Gordon, Wren, Brendan W

“…The continued rise of Clostridium difficile infections worldwide has been accompanied by the rapid emergence of a highly virulent clone designated PCR-ribotype…”
Get full text

Transcriptional analysis of temporal gene expression in germinating Clostridium difficile 630 endospores by Dembek, Marcin, Stabler, Richard A, Witney, Adam A, Wren, Brendan W, Fairweather, Neil F

“…Clostridium difficile is the leading cause of hospital acquired diarrhoea in industrialised countries. Under conditions that are not favourable for growth, the…”
Get full text

The Genotoxin Colibactin Is a Determinant of Virulence in Escherichia coli K1 Experimental Neonatal Systemic Infection by McCarthy, Alex J, Martin, Patricia, Cloup, Emilie, Stabler, Richard A, Oswald, Eric, Taylor, Peter W

“…Escherichia coli strains expressing the K1 capsule are a major cause of sepsis and meningitis in human neonates. The development of these diseases is dependent…”
Get full text

Genome-Wide Identification by Transposon Insertion Sequencing of Escherichia coli K1 Genes Essential for In Vitro Growth, Gastrointestinal Colonizing Capacity, and Survival in Serum by McCarthy, Alex J, Stabler, Richard A, Taylor, Peter W

“…K1 strains are major causative agents of invasive disease of newborn infants. The age dependency of infection can be reproduced in neonatal rats. Colonization…”
Get full text

Fabrication of a foldable all-in-one point-of-care molecular diagnostic microdevice for the facile identification of multiple pathogens by Trinh, Kieu The Loan, Stabler, Richard A., Lee, Nae Yoon

“…•A foldable all-in-one point‐of‐care microdevice enabled multiplex detection of pathogens.•DNA extraction, amplification, and detection were performed in a…”
Get full text

Macro and micro diversity of Clostridium difficile isolates from diverse sources and geographical locations by Stabler, Richard A, Dawson, Lisa F, Valiente, Esmeralda, Cairns, Michelle D, Martin, Melissa J, Donahue, Elizabeth H, Riley, Thomas V, Songer, J Glenn, Kuijper, Ed J, Dingle, Kate E, Wren, Brendan W

“…Clostridium difficile has emerged rapidly as the leading cause of antibiotic-associated diarrheal disease, with the temporal and geographical appearance of…”
Get full text

Evidence for Community Transmission of Community-Associated but Not Health-Care-Associated Methicillin-Resistant Staphylococcus Aureus Strains Linked to Social and Material Deprivation: Spatial Analysis of Cross-sectional Data by Tosas Auguet, Olga, Betley, Jason R, Stabler, Richard A, Patel, Amita, Ioannou, Avgousta, Marbach, Helene, Hearn, Pasco, Aryee, Anna, Goldenberg, Simon D, Otter, Jonathan A, Desai, Nergish, Karadag, Tacim, Grundy, Chris, Gaunt, Michael W, Cooper, Ben S, Edgeworth, Jonathan D, Kypraios, Theodore

“…Identifying and tackling the social determinants of infectious diseases has become a public health priority following the recognition that individuals with…”
Get full text

Carriage and antimicrobial susceptibility of commensal Neisseria species from the human oropharynx by Miari, Victoria F., Bonnin, Wesley, Smith, Imogen K. G., Horney, Megan F., Saint-Geris, Samer J., Stabler, Richard A.

“…Commensal Neisseria ( N c) mainly occupy the oropharynx of humans and animals. These organisms do not typically cause disease; however, they can act as a…”
Get full text

Antibiotic Treatment of Clostridium difficile Carrier Mice Triggers a Supershedder State, Spore-Mediated Transmission, and Severe Disease in Immunocompromised Hosts by Lawley, Trevor D, Clare, Simon, Walker, Alan W, Goulding, David, Stabler, Richard A, Croucher, Nicholas, Mastroeni, Piero, Scott, Paul, Raisen, Claire, Mottram, Lynda, Fairweather, Neil F, Wren, Brendan W, Parkhill, Julian, Dougan, Gordon

“…Clostridium difficile persists in hospitals by exploiting an infection cycle that is dependent on humans shedding highly resistant and infectious spores. Here…”
Get full text

The association between antimicrobial resistance and HIV infection: a systematic review and meta-analysis by Olaru, Ioana D., Tacconelli, Evelina, Yeung, Shunmay, Ferrand, Rashida A., Stabler, Richard A., Hopkins, Heidi, Aiken, Alexander M., Kranzer, Katharina

“…People living with HIV (PLWH) are at increased risk of infections with resistant organisms due to more frequent healthcare utilization. Our objective was to…”
Get full text

Impact of Eimeria tenella Coinfection on Campylobacter jejuni Colonization of the Chicken by Macdonald, Sarah E, van Diemen, Pauline M, Martineau, Henny, Stevens, Mark P, Tomley, Fiona M, Stabler, Richard A, Blake, Damer P

“…can cause the disease coccidiosis in chickens. The direct and often detrimental impact of this parasite on chicken health, welfare, and productivity is well…”
Get full text

Evolutionary dynamics of Clostridium difficile over short and long time scales by He, Miao, Sebaihia, Mohammed, Lawley, Trevor D, Stabler, Richard A, Dawson, Lisa F, Martin, Melissa J, Holt, Kathryn E, Seth-Smith, Helena M.B, Quail, Michael A, Rance, Richard, Brooks, Karen, Churcher, Carol, Harris, David, Bentley, Stephen D, Burrows, Christine, Clark, Louise, Corton, Craig, Murray, Vicky, Rose, Graham, Thurston, Scott, van Tonder, Andries, Walker, Danielle, Wren, Brendan W, Dougan, Gordon, Parkhill, Julian

“…Clostridium difficile has rapidly emerged as the leading cause of antibiotic-associated diarrheal disease, with the transcontinental spread of various PCR…”
Get full text

The induction and identification of novel Colistin resistance mutations in Acinetobacter baumannii and their implications by Thi Khanh Nhu, Nguyen, Riordan, David W., Do Hoang Nhu, Tran, Thanh, Duy Pham, Thwaites, Guy, Huong Lan, Nguyen Phu, Wren, Brendan W., Baker, Stephen, Stabler, Richard A

“…Acinetobacter baumannii is a significant cause of opportunistic hospital acquired infection and has been identified as an important emerging infection due to…”
Get full text

Genomic and Phenotypic Analyses of Acinetobacter baumannii Isolates From Three Tertiary Care Hospitals in Thailand by Loraine, Jessica, Heinz, Eva, Soontarach, Rosesathorn, Blackwell, Grace A, Stabler, Richard A, Voravuthikunchai, Supayang P, Srimanote, Potjanee, Kiratisin, Pattarachai, Thomson, Nicholas R, Taylor, Peter W

“…Antibiotic resistant strains of are responsible for a large and increasing burden of nosocomial infections in Thailand and other countries of Southeast Asia…”
Get full text

Strain Specific Variations in Acinetobacter baumannii Complement Sensitivity by Kamuyu, Gathoni, Ercoli, Giuseppe, Ramos-Sevillano, Elisa, Willcocks, Sam, Kewcharoenwong, Chidchamai, Kiratisin, Pattarachai, Taylor, Peter W, Wren, Brendan W, Lertmemongkolchai, Ganjana, Stabler, Richard A, Brown, Jeremy S

“…The complement system is required for innate immunity against , an important cause of antibiotic resistant systemic infections. strains differ in their…”
Get full text

Pathoadaptive Mutations of Escherichia coli K1 in Experimental Neonatal Systemic Infection by McCarthy, Alex J, Negus, David, Martin, Patricia, Pechincha, Catarina, Oswald, Eric, Stabler, Richard A, Taylor, Peter W

“…Although Escherichia coli K1 strains are benign commensals in adults, their acquisition at birth by the newborn may result in life-threatening systemic…”
Get full text

Emergence of new PCR ribotypes from the hypervirulent Clostridium difficile 027 lineage by VALIENTE, Esmeralda, DAWSON, Lisa F, CAIRNS, Michelle D, STABLER, Richard A, WREN, Brendan W

“…Clostridium difficile is the most common cause of antibiotic-associated diarrhoea worldwide. Over the past 10 years, the incidence and severity of disease have…”
Get full text

In Vitro Susceptibility to Closthioamide among Clinical and Reference Strains of Neisseria gonorrhoeae by Miari, Victoria F, Solanki, Priya, Hleba, Yonek, Stabler, Richard A, Heap, John T

“…is one of the leading antimicrobial resistance threats worldwide. This study determined the MICs of closthioamide to be 0.008 to 0.5 mg/liter for clinical…”
Get full text