Search Results - "Staats, HF"

Cardiolipin Polyspecific Autoreactivity in Two Broadly Neutralizing HIV-1 Antibodies by Haynes, Barton F, Fleming, Judith, St. Clair, E. William, Katinger, Herman, Stiegler, Gabriela, Kunert, Renate, Robinson, James, Scearce, Richard M, Plonk, Kelly, Staats, Herman F, Ortel, Thomas L, Liao, Hua-Xin, Alam, S. Munir

“…The design of a human immunodeficiency virus-1 (HIV-1) immunogen that can induce broadly reactive neutralizing antibodies is a major goal of HIV-1 vaccine…”
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Mast cell-derived tumor necrosis factor induces hypertrophy of draining lymph nodes during infection by Abraham, Soman N, McLachlan, James B, Hart, Justin P, Pizzo, Salvatore V, Shelburne, Christopher P, Staats, Herman F, Gunn, Michael D

“…Palpable swelling of regional lymph nodes is a common sequela of microbial infections but the mechanism responsible for the sequestration and subsequent…”
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Mucosal and Systemic Adjuvant Activity of Alphavirus Replicon Particles by Thompson, Joseph M., Whitmore, Alan C., Konopka, Jennifer L., Collier, Martha L., Richmond, Erin M. B., Davis, Nancy L., Staats, Herman F., Johnston, Robert E.

“…Vaccination represents the most effective control measure in the fight against infectious diseases. Local mucosal immune responses are critical for protection…”
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Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4 by Marinaro, M, Staats, HF, Hiroi, T, Jackson, RJ, Coste, M, Boyaka, PN, Okahashi, N, Yamamoto, M, Kiyono, H, Bluethmann, H

“…Despite pathophysiologic effects including diarrhea, cholera toxin (CT) is a potent mucosal immunogen and adjuvant. We investigated the influence of CT on T…”
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IL-1 Is an Effective Adjuvant for Mucosal and Systemic Immune Responses When Coadministered with Protein Immunogens by Staats, Herman F, Ennis, Francis A., Jr

“…Mucosal immunization with soluble protein Ag alone may induce Ag-specific tolerance, whereas mucosal immunization with Ag in the presence of a mucosal adjuvant…”
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An In Vitro Model of Mast Cell Desensitization by Hofmann, A.M, Jin, C, Staats, H.F, Abraham, S.N

“…Murine bone marrow derived MCs were sensitized with anti-TNP IgE…”
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Use of a Mast Cell Activator as a Mucosal Adjuvant for Pertussis Vaccines by Hofmann, A.M, Staats, H.F, Abraham, S.N

“…The mast cell activator, C48/80, is a powerful adjuvant for pertussis nasal vaccines capable of evoking strong systemic and nasal immune responses, which is…”
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Cytokines as Adjuvants for the Induction of Anti-Human Immunodeficiency Virus Peptide Immunoglobulin G (IgG) and IgA Antibodies in Serum and Mucosal Secretions after Nasal Immunization by Bradney, Curtis P, Sempowski, Gregory D, Liao, Hua-Xin, Haynes, Barton F, Staats, Herman F

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Dry powder vaccines for mucosal administration: critical factors in manufacture and delivery by Wang, Sheena H, Thompson, Afton L, Hickey, Anthony J, Staats, Herman F

“…Dry powder vaccine formulations have proved effective for induction of systemic and mucosal immune responses. Here we review the use of dry vaccines for…”
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Regulation of mucosal and systemic antibody responses by T helper cell subsets, macrophages, and derived cytokines following oral immunization with live recombinant Salmonella by VanCott, JL, Staats, HF, Pascual, DW, Roberts, M, Chatfield, SN, Yamamoto, M, Coste, M, Carter, PB, Kiyono, H, McGhee, JR

“…We have assessed regulatory Th cell and cytokine responses in mice after oral immunization with recombinant Salmonella (BRD 847) expressing fragment C of…”
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Cytokine Requirements for Induction of Systemic and Mucosal CTL After Nasal Immunization by Staats, Herman F, Bradney, Curtis P, Gwinn, William M, Jackson, Shawn S, Sempowski, Gregory D, Liao, Hua-Xin, Letvin, Norman L, Haynes, Barton F

“…Cholera toxin (CT) is frequently used as an experimental adjuvant intranasally for the induction of systemic and mucosal immunity. However, CT is highly…”
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A Novel Neurotoxoid Vaccine Prevents Mucosal Botulism by Kobayashi, Ryoki, Kohda, Tomoko, Kataoka, Kosuke, Ihara, Hideshi, Kozaki, Shunji, Pascual, David W, Staats, Herman F, Kiyono, Hiroshi, McGhee, Jerry R, Fujihashi, Kohtaro

“…The threat posed by botulism, classically a food- and waterborne disease with a high morbidity and mortality, has increased exponentially in an age of…”
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Helper T cell subsets for immunoglobulin A responses : oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosa associated tissues by XU-AMANO, J, KIYONO, H, JACKSON, R. J, STAATS, H. F, FUJIHASHI, K, BURROWS, P. D, ELSON, C. O, PILLAI, S, MCGHEE, J. R

“…Antigen-specific B cell responses to mucosally delivered proteins are dependent upon CD4-positive T helper (Th) cells, and the frequency of Th1 and Th2 cell…”
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Mucosal immunity to HIV-1: systemic and vaginal antibody responses after intranasal immunization with the HIV-1 C4/V3 peptide T1SP10 MN(A) by Staats, HF, Nichols, WG, Palker, TJ

“…To optimize mucosal immune responses to the HIV-1 peptide vaccine candidate T1SP10 MN(A), we intranasally immunized BALB/c and C57BL/6 mice with C4/V3 HIV-1…”
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A comparative evaluation of nasal and parenteral vaccine adjuvants to elicit systemic and mucosal HIV-1 peptide-specific humoral immune responses in cynomolgus macaques by Egan, Michael A, Chong, Siew Yen, Hagen, Michael, Megati, Shakuntala, Schadeck, Eva B, Piacente, Priscilla, Ma, Ben-Jiang, Montefiori, David C, Haynes, Barton F, Israel, Zimra R, Eldridge, John H, Staats, Herman F

“…Cynomolgus macaques were immunized by either the intramuscular (i.m.) or intranasal (i.n.) route with a HIV-1 peptide-based immunogen (C4-V3 89.6P) alone, or…”
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Prolonged CD4+ Cell/Virus Load Discordance during Treatment with Protease Inhibitor–Based Highly Active Antiretroviral Therapy: Immune Response and Viral Control by Sufka, Susan A, Ferrari, Guido, Gryszowka, Victoria E, Wrin, Terri, Fiscus, Susan A, Tomaras, Georgia D, Staats, Herman F, Patel, Dhavalkumar D, Sempowski, Gregory D, Hellmann, Nicholas S, Weinhold, Kent J, Hicks, Charles B

“…Mechanisms that underly discordant CD4+ cell/virus load (VL) responses in patients who receive highly active antiretroviral therapy (HAART) were studied in 30…”
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Human Nasopharyngeal-Associated Lymphoreticular Tissues : Functional Analysis of Subepithelial and Intraepithelial B and T Cells from Adenoids and Tonsils by Boyaka, Prosper N, Wright, Peter F, Marinaro, Mariarosaria, Kiyono, Hiroshi, Johnson, Joyce E, Gonzales, Ricardo A, Ikizler, Mine R, Werkhaven, Jay A, Jackson, Raymond J, Fujihashi, Kohtaro, Di Fabio, Simonetta, Staats, Herman F, McGhee, Jerry R

“…Subepithelial and intraepithelial lymphocytes of human adenoids and tonsils were characterized and directly compared to determine the potential contribution of…”
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Detection of mucosal antibodies in HIV type 1-infected individuals by Wright, Peter F, Kozlowski, Pamela A, Rybczyk, G Kyle, Goepfert, Paul, Staats, Herman F, VanCott, Thomas C, Trabattoni, Daria, Sannella, Edith, Mestecky, Jiri

“…HIV-1-specific mucosal IgA antibodies may correlate with protection in highly exposed but uninfected individuals, but have been detected at highly variable…”
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Intranasal immunization with CTL epitope peptides from HIV-1 or ovalbumin and the mucosal adjuvant cholera toxin induces peptide- specific CTLs and protection against tumor development in vivo by Porgador, A, Staats, HF, Faiola, B, Gilboa, E, Palker, TJ

“…To evaluate the ability of mucosal immunization protocols using peptide immunogens to induce CTL responses, BALB/c and C57BL/6 mice were immunized intranasally…”
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Mucosal immunity to infection with implications for vaccine development by Staats, H F, Jackson, R J, Marinaro, M, Takahashi, I, Kiyono, H, McGhee, J R

“…The induction of effective mucosal immunity that also provides systemic immunity is a considerable challenge. Over the past two years, efforts to develop novel…”
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