Search Results - "Staas, Jay K"

Use of Microsphere Technology for Targeted Delivery of Rifampin to Mycobacterium tuberculosis-Infected Macrophages by BARROW, E. L. W, WINCHESTER, G. A, STAAS, J. K, QUENELLE, D. C, BARROW, W. W

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Treatment of Tuberculosis Using a Combination of Sustained-Release Rifampin-Loaded Microspheres and Oral Dosing with Isoniazid by QUENELLE, Debra C, WINCHESTER, Gary A, STAAS, Jay K, BARROW, Esther L. W, BARROW, William W

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Protection Against Vaginal SIV Transmission with Microencapsulated Vaccine by Marx, Preston A., Compans, Richard W., Gettie, Agegnehu, Staas, Jay K., Gilley, Richard M., Mulligan, Mark J., Yamshchikov, Galina V., Chen, Dexiang, Eldridge, John H.

“…Although protection in animal models against intravenous challenges with simian immunodeficiency virus (SIV) has been reported, no previous vaccines have…”
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Efficacy of rifabutin-loaded microspheres for treatment of Mycobacterium avium-infected macrophages and mice by Barrow, Esther L W, Barrow, William W, Quenelle, Debra C, Westbrook, Louise, Winchester, Gary A, Staas, Jay K

“…Two poly(DL-lactide-co-glycolide) microsphere formulations (A, 10% wt/wt, and B, 23% wt/wt, 1-10 microns) were evaluated for intracellular delivery of…”
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The fate of biodegradable microspheres injected into rat brain by Nicholas, Anthony P., McInnis, Carey, Gupta, Kiran B., Snow, William W., Love, Darryl F., Mason, David W., Ferrell, Teresa M., Staas, Jay K., Tice, Thomas R.

“…Biodegradable microspheres made with poly-[ d, l-lactide-co-glycolide] represent an evolving technology for drug delivery into the central nervous system. Even…”
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Sustained release characteristics of rifampin-loaded microsphere formulations in nonhuman primates by Quenelle, Debra, Winchester, Gary A, Staas, Jay K, Hoskins, Darrel E, Barrow, Esther W, Barrow, William W

“…Controlled release rifampin-loaded microspheres were evaluated for the first time in nonhuman primates. Animals received either 2.0 g of a large formulation…”
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Efficacy of Microencapsulated Rifampin inMycobacterium tuberculosis-Infected Mice by Quenelle, Debra C, Staas, Jay K, Winchester, Gary A, Barrow, Esther L. W, Barrow, William W

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Biodegradable microspheres as a vaccine delivery system by Eldridge, J H, Staas, J K, Meulbroek, J A, McGhee, J R, Tice, T R, Gilley, R M

“…The utility of biodegradable and biocompatible microspheres as a vaccine delivery system for the induction of systemic and disseminated mucosal antibody…”
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Efficacy of microencapsulated rifampin in Mycobacterium tuberculosis-infected mice by QUENELLE, D. C, STAAS, J. K, WINCHESTER, G. A, BARROW, E. L. W, BARROW, W. W

“…Rifampin is a first-line drug useful in the treatment of tuberculosis. By using biocompatible polymeric excipients of lactide and glycolide copolymers, two…”
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Oral Immunization with Influenza Virus in Biodegradable Microspheres by Moldoveanu, Zina, Novak, Miroslav, Huang, Wen-Qiang, Gilley, Richard M., Staas, Jay K., Schafer, Dennis, Compans, Richard W., Mestecky, Jiri

“…Polymeric microspheres were evaluated as an oral antigen delivery system for immunization with influenza virus. The immune responses obtained were compared…”
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Induction of protective immune responses against Venezuelan equine encephalitis (VEE) virus aerosol challenge with microencapsulated VEE virus vaccine by Greenway, Terrence E., Eldridge, John H., Ludwig, George, Staas, Jay K., Smith, Jonathan F., Gilley, Richard M., Michalek, Suzanne M.

“…Venezuelan equine encephalomyelitis (VEE) virus, a member of the family Togaviridae, genus Alphavirus, causes disease in humans and equids. The virus is…”
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Vaccine-containing biodegradable microspheres specifically enter the gut-associated lymphoid tissue following oral administration and induce a disseminated mucosal immune response by Eldridge, J H, Meulbroek, J A, Staas, J K, Tice, T R, Gilley, R M

“…Biodegradable and biocompatible microspheres have been investigated for their usefulness as a vaccine delivery system for both parenteral and enteral…”
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Enhancement of protective immune responses to Venezuelan equine encephalitis (VEE) virus with microencapsulated vaccine by Greenway, Terrence E., Eldridge, John H., Ludwig, George, Staas, Jay K., Smith, Jonathan F., Gilley, Richard M., Michalek, Suzanne M.

“…Venezuelan equine encephalomyelitis (VEE) virus is a mosquito-borne arbovirus of major human health significance in the New World. Currently two forms of VEE…”
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Induction of mucosal antibody responses by microsphere-encapsulated formalin-inactivated simian immunodeficiency virus in a male urethral challenge model by Ishizaka, Sally T., Israel, Zimra R., Gettie, Agegnehu, Mishkin, Eric M., Staas, Jay K., Gilley, Richard M., Dailey, Peter J., Montefiori, David C., Marx, Preston A., Eldridge, John H.

“…Male rhesus macaques were immunized mucosally with microsphere-encapsulated formalin-inactivated simian immunodeficiency virus (SIV) particles in a test of…”
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