Search Results - "St. J. Bird, Gary"

Capacitative calcium entry supports calcium oscillations in human embryonic kidney cells by Gary St. J Bird, James W Putney, Jr

“…Treatment of human epithelial kidney (HEK293) cells with low concentrations of the muscarinic agonist methacholine results in the activation of complex and…”
Get full text

Negative regulation of TRPC3 channels by protein kinase C-mediated phosphorylation of serine 712 by Trebak, Mohamed, Hempel, Nadine, Wedel, Barbara J, Smyth, Jeremy T, Bird, Gary St J, Putney, Jr, James W

“…TRPC3 is a nonselective cation channel member of the "canonical" transient receptor potential (TRPC) family whose members are activated by phospholipase…”
Get more information

Signaling Mechanism for Receptor-activated Canonical Transient Receptor Potential 3 (TRPC3) Channels by Trebak, Mohamed, St. J. Bird, Gary, McKay, Richard R., Birnbaumer, Lutz, Putney, James W.

“…Canonical transient receptor potential 3 (TRPC3) is a receptor-activated, calcium permeant, non-selective cation channel. TRPC3 has been shown to interact…”
Get full text

Canonical transient receptor potential TRPC7 can function as both a receptor- and store-operated channel in HEK-293 cells by Lièvremont, Jean-Philippe, Bird, Gary St J, Putney, Jr, James W

“…Previous studies on the activation mechanism of canonical transient receptor potential (TRPC) channels have often produced conflicting conclusions. All seven…”
Get more information

Human Trp3 Forms Both Inositol Trisphosphate Receptor-Dependent and Receptor-Independent Store-Operated Cation Channels in DT40 Avian B Lymphocytes by Vazquez, Guillermo, Lievremont, Jean-Philippe, Gary St. J. Bird, Putney, James W.

“…Mammalian Trp proteins are candidates for plasma membrane calcium channels regulated by receptor activation or by intracellular calcium store depletion…”
Get full text

Native TRPC7 Channel Activation by an Inositol Trisphosphate Receptor-dependent Mechanism by Vazquez, Guillermo, Bird, Gary St. J., Mori, Yasuo, Putney, James W.

“…In DT40 B lymphocytes, Canonical Transient Receptor Potential 7 (TRPC7) functions as a diacylglycerol-activated non-selective cation channel. However, previous…”
Get full text

A Calmodulin/Inositol 1,4,5-Trisphosphate (IP3) Receptor-binding Region Targets TRPC3 to the Plasma Membrane in a Calmodulin/IP3 Receptor-independent Process by Wedel, Barbara J., Vazquez, Guillermo, McKay, Richard R., St. J. Bird, Gary, Putney, James W.

“…Conformational coupling with the inositol 1,4,5-trisphosphate (IP3) receptor has been suggested as a possible mechanism of activation of TRPC3 channels and a…”
Get full text

Mechanisms of capacitative calcium entry by Putney, Jr, J W, Broad, L M, Braun, F J, Lievremont, J P, Bird, G S

“…Capacitative Ca(2+) entry involves the regulation of plasma membrane Ca(2+) channels by the filling state of intracellular Ca(2+) stores in the endoplasmic…”
Get full text

Role of the Phospholipase C-Inositol 1,4,5-Trisphosphate Pathway in Calcium Release-activated Calcium Current and Capacitative Calcium Entry by Broad, Lisa M., Braun, Franz-Josef, Lievremont, Jean-Philippe, Bird, Gary St. J., Kurosaki, Tomohiro, Putney, James W.

“…We investigated the putative roles of phospholipase C, polyphosphoinositides, and inositol 1,4,5-trisphosphate (IP3) in capacitative calcium entry and calcium…”
Get full text

Signaling Pathways Underlying Muscarinic Receptor-induced [Ca2+]i Oscillations in HEK293 Cells by Luo, Dali, Broad, Lisa M., St. J. Bird, Gary, Putney, James W.

“…We have investigated the signaling pathways underlying muscarinic receptor-induced calcium oscillations in human embryonic kidney (HEK293) cells. Activation of…”
Get full text

Comparison of human TRPC3 channels in receptor-activated and store-operated modes. Differential sensitivity to channel blockers suggests fundamental differences in channel composition by Trebak, Mohamed, Bird, Gary St J, McKay, Richard R, Putney, Jr, James W

“…Capacitative calcium entry or store-operated calcium entry in nonexcitable cells is a process whereby the activation of calcium influx across the plasma…”
Get full text

The TRPC3/6/7 subfamily of cation channels by Trebak, Mohamed, Vazquez, Guillermo, Bird, Gary St.J., Putney, James W.

“…The mammalian transient receptor potential (TRP) proteins consist of a superfamily of Ca 2+-permeant non-selective cation channels with structural similarities…”
Get full text

Techniques: high-throughput measurement of intracellular Ca(2+) -- back to basics by Monteith, Gregory R, Bird, Gary St J

“…High-throughput screening techniques continue to provide important tools to the pharmaceutical industry for the efficient identification of drug leads…”
Get full text

Signaling Pathways Underlying Muscarinic Receptor-induced [Ca2+] Oscillations in HEK293 Cells by Luo, Dali, Broad, Lisa M., St. J. Bird, Gary, Putney, James W.

Get full text

Spatial and temporal aspects of cellular calcium signaling by Thomas, A P, Bird, G S, Hajnóczky, G, Robb-Gaspers, L D, Putney, Jr, J W

“…Cytosolic Ca2+ signals are often organized in complex temporal and spatial patterns, even under conditions of sustained stimulation. In this review we discuss…”
Get more information

The inositol phosphate-calcium signaling system in nonexcitable cells by Putney, Jr, J W, Bird, G S

Get more information

The signal for capacitative calcium entry by Putney, Jr, J W, Bird, G S

Get more information

An inositol 1,4,5-trisphosphate receptor-dependent cation entry pathway in DT40 B lymphocytes by Vazquez, Guillermo, Wedel, Barbara J., Bird, Gary St J., Joseph, Suresh K., Putney Jr, James W.

“…We examined the roles of inositol 1,4,5‐trisphosphate (IP3) receptors (IP3R) in calcium signaling using DT40 B lymphocytes, and a variant lacking the three…”
Get full text

Mutual Antagonism of Calcium Entry by Capacitative and Arachidonic Acid-mediated Calcium Entry Pathways by Luo, Dali, Broad, Lisa M., Bird, Gary St.J., Putney, James W.

“…In nonexcitable cells, the predominant mechanism for regulated entry of Ca2+ is capacitative calcium entry, whereby depletion of intracellular Ca2+ stores…”
Get full text

A Selective Requirement for Elevated Calcium in DNA Degradation, but Not Early Events in Anti-Fas-induced Apoptosis by Scoltock, Alyson B., Bortner, Carl D., St. J. Bird, Gary, Putney, James W., Cidlowski, John A.

“…Jurkat cells undergo apoptosis in response to anti-Fas antibody through a caspase-dependent death cascade in which calcium signaling has been implicated. We…”
Get full text