Search Results - "St Lawrence, Keith S"
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caliPER: A software for blood-free parametric Patlak mapping using PET/MRI input function
Published in NeuroImage (Orlando, Fla.) (01-08-2022)“…•caliPER is an adaptable image processing software for extracting image-derived input functions and generating parametric maps of irreversible PET tracer…”
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A two-stage approach for measuring vascular water exchange and arterial transit time by diffusion-weighted perfusion MRI
Published in Magnetic resonance in medicine (01-05-2012)“…Changes in the exchange rate of water across the blood‐brain barrier, denoted kw, may indicate blood‐brain barrier dysfunction before the leakage of…”
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Turbo-FLASH based arterial spin labeled perfusion MRI at 7 T
Published in PloS one (20-06-2013)“…Motivations of arterial spin labeling (ASL) at ultrahigh magnetic fields include prolonged blood T1 and greater signal-to-noise ratio (SNR). However, increased…”
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Water Exchange across the Blood-Brain Barrier in Obstructive Sleep Apnea: An MRI Diffusion-Weighted Pseudo-Continuous Arterial Spin Labeling Study
Published in Journal of neuroimaging (01-11-2015)“…ABSTRACT BACKGROUND AND PURPOSE Obstructive sleep apnea (OSA) subjects show brain injury in sites that control autonomic, cognitive, and mood functions that…”
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Using simultaneous PET/MRI to compare the accuracy of diagnosing frontotemporal dementia by arterial spin labelling MRI and FDG-PET
Published in NeuroImage clinical (01-01-2018)“…The clinical utility of FDG-PET in diagnosing frontotemporal dementia (FTD) has been well demonstrated over the past decades. On the contrary, the diagnostic…”
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Impaired Cerebrovascular Function in Coronary Artery Disease Patients and Recovery Following Cardiac Rehabilitation
Published in Frontiers in aging neuroscience (05-01-2016)“…Coronary artery disease (CAD) poses a risk to the cerebrovascular function of older adults and has been linked to impaired cognitive abilities. Using magnetic…”
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When Perfusion Meets Diffusion: in vivo Measurement of Water Permeability in Human Brain
Published in Journal of cerebral blood flow and metabolism (01-04-2007)“…Quantification of water permeability can improve the accuracy of perfusion measurements obtained with arterial spin labeling (ASL) methods, and may provide…”
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Noninvasive MRI Measures of Microstructural and Cerebrovascular Changes During Normal Swine Brain Development
Published in Pediatric research (01-05-2011)“…The swine brain is emerging as a potentially valuable translational animal model of neurodevelopment and offers the ability to assess the impact of…”
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Validation study of a pulsed arterial spin labeling technique by comparison to perfusion computed tomography
Published in Magnetic resonance imaging (01-05-2008)“…Abstract Abnormalities in cerebral blood flow (CBF) are believed to play a significant role in the development of major neonatal neuropathologies. One approach…”
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Using perfusion MRI to measure the dynamic changes in neural activation associated with tonic muscular pain
Published in Pain (Amsterdam) (01-03-2010)“…Knowledge regarding neural pain processing is primarily the result of studies involving models of brief cutaneous pain; however, clinical pain generally…”
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Quantification of renal perfusion: Comparison of arterial spin labeling and dynamic contrast-enhanced MRI
Published in Journal of magnetic resonance imaging (01-09-2011)“…Purpose: To provide the first comparison of absolute renal perfusion obtained by arterial spin labeling (ASL) and separable compartment modeling of dynamic…”
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Feasibility of simultaneous whole-brain imaging on an integrated PET-MRI system using an enhanced 2-point Dixon attenuation correction method
Published in Frontiers in neuroscience (05-01-2015)“…To evaluate a potential approach for improved attenuation correction (AC) of PET in simultaneous PET and MRI brain imaging, a straightforward approach that…”
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Measuring the neural response to continuous intramuscular infusion of hypertonic saline by perfusion MRI
Published in Journal of magnetic resonance imaging (01-03-2012)“…Purpose: To determine the extent to which arterial spin labeling (ASL), a functional magnetic resonance imaging technique that directly measures cerebral blood…”
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An adiabatic approximation to the tissue homogeneity model for water exchange in the brain: I. Theoretical derivation
Published in Journal of cerebral blood flow and metabolism (01-12-1998)“…Using the adiabatic approximation, which assumes that the tracer concentration in parenchymal tissue changes slowly relative to that in capillaries, we derived…”
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Quantification of blood–brain barrier water exchange and permeability with multidelay diffusion‐weighted pseudo‐continuous arterial spin labeling
Published in Magnetic resonance in medicine (01-05-2023)“…Purpose To present a pulse sequence and mathematical models for quantification of blood–brain barrier water exchange and permeability. Methods…”
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An adiabatic approximation to the tissue homogeneity model for water exchange in the brain: II. Experimental validation
Published in Journal of cerebral blood flow and metabolism (01-12-1998)“…A frequently reported limitation to using water as a tracer for measuring CBF has been the dependence of the CBF estimate on the experimental time (referred to…”
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A model of blood-brain barrier permeability to water: Accounting for blood inflow and longitudinal relaxation effects
Published in Magnetic resonance in medicine (01-06-2002)“…A noninvasive technique for measuring the permeability of the blood–brain barrier (BBB) to water could help to evaluate changes in the functional integrity of…”
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Quantification issues in arterial spin labeling perfusion magnetic resonance imaging
Published in Topics in magnetic resonance imaging (01-04-2010)“…Arterial spin labeling (ASL) perfusion magnetic resonance imaging has gained wide acceptance for its value in clinical and neuroscience applications during…”
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Feasibility and precision of cerebral blood flow and cerebrovascular reactivity MRI measurements using a computer-controlled gas delivery system in an anesthetised juvenile animal model
Published in Journal of magnetic resonance imaging (01-11-2010)“…Purpose: To demonstrate the feasibility and repeatability of cerebrovascular reactivity (CVR) imaging using a controlled CO2 challenge in mechanically…”
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Quantification of Blood-Brain Barrier Water Exchange and Permeability with Multi-delay Diffusion Weighted pCASL
Published in Magnetic resonance in medicine (09-01-2023)Get full text
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