Search Results - "St John, Nick"
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High-throughput screening of the Saccharomyces cerevisiae genome for 2-amino-3-methylimidazo [4,5-f] quinoline resistance identifies colon cancer-associated genes
Published in G3 : genes - genomes - genetics (06-12-2023)“…Abstract Heterocyclic aromatic amines (HAAs) are potent carcinogenic agents found in charred meats and cigarette smoke. However, few eukaryotic resistance…”
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Prevention of traumatic stress in mothers of preterms: 6-month outcomes
Published in Pediatrics (Evanston) (01-08-2014)“…Symptoms of posttraumatic stress disorder are a well-recognized phenomenon in mothers of preterm infants, with implications for maternal health and infant…”
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Genome Profiling for Aflatoxin B1 Resistance in Saccharomyces cerevisiae Reveals a Role for the CSM2/SHU Complex in Tolerance of Aflatoxin B1-Associated DNA Damage
Published in G3 : genes - genomes - genetics (01-11-2020)“…Abstract Exposure to the mycotoxin aflatoxin B1 (AFB1) strongly correlates with hepatocellular carcinoma (HCC). P450 enzymes convert AFB1 into a highly…”
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DOES AN INTERVENTION TO REDUCE MATERNAL ANXIETY, DEPRESSION AND TRAUMA ALSO IMPROVE MOTHERS’ PERCEPTIONS OF THEIR PRETERM INFANTS’ VULNERABILITY?
Published in Infant mental health journal (01-01-2015)“…ABSTRACT To determine if an intervention to reduce maternal distress and address maternal perceptions of infants’ vulnerability also reduces perceptions of…”
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Prevention of traumatic stress in mothers with preterm infants: a randomized controlled trial
Published in Pediatrics (Evanston) (01-10-2013)“…The current study evaluates a treatment intervention developed with the goal of reducing symptoms of posttraumatic stress, depression, and anxiety in parents…”
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A model for the development of mothers' perceived vulnerability of preterm infants
Published in Journal of developmental and behavioral pediatrics (01-06-2015)“…Some mothers of preterm infants continue to view them as vulnerable after their health has improved. These exaggerated perceptions of vulnerability lead to…”
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Genome Profiling for Aflatoxin B 1 Resistance in Saccharomyces cerevisiae Reveals a Role for the CSM2/SHU Complex in Tolerance of Aflatoxin B 1 -Associated DNA Damage
Published in G3 : genes - genomes - genetics (05-11-2020)“…Exposure to the mycotoxin aflatoxin B1 (AFB ) strongly correlates with hepatocellular carcinoma (HCC). P450 enzymes convert AFB into a highly reactive epoxide…”
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An in vitro system for measuring genotoxicity mediated by human CYP3A4 in Saccharomyces cerevisiae
Published in Environmental and molecular mutagenesis (01-05-2017)“…P450 activity is required to metabolically activate many chemical carcinogens, rendering them highly genotoxic. CYP3A4 is the most abundantly expressed P450…”
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Prevention of Postpartum Traumatic Stress in Mothers with Preterm Infants: Manual Development and Evaluation
Published in Issues in mental health nursing (01-08-2013)“…Premature birth has been associated with multiple adverse maternal psychological outcomes that include depression, anxiety, and trauma as well as adverse…”
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