Search Results - "Stȩpień, Ewa"
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Zinc oxide nanoparticles impair the integrity of human umbilical vein endothelial cell monolayer in vitro
Published in Journal of biomedical nanotechnology (01-12-2012)“…Disruption of the intercellular interactions between endothelial cells leads to endothelial dysfunction. The role of nanoparticles in plasma membrane…”
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Frailty syndrome in daily practice of interventional cardiology ward-rationale and design of the FRAPICA trial: A STROBE-compliant prospective observational study
Published in Medicine (Baltimore) (01-01-2020)“…The effect of frailty on short and long term results of interventional treatment of coronary heart disease is not well defined. The evaluation of frailty may…”
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Diagnostic and prognostic micro-RNAs in ischaemic stroke due to carotid artery stenosis and in acute coronary syndrome: a four-year prospective study
Published in Kardiologia polska (01-01-2018)“…Circulating microRNAs (miRs) levels are potentially important diagnostic and prognostic biomarkers in acute coronary syndrome (ACS) or cerebral ischaemic…”
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Stiffness memory of EA.hy926 endothelial cells in response to chronic hyperglycemia
Published in Cardiovascular diabetology (27-06-2013)“…Glycemic memory of endothelial cells is an effect of long-lasting hyperglycemia and is a cause of various diabetics complications, that arises despite of the…”
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Prospects and Clinical Perspectives of Total-Body PET Imaging Using Plastic Scintillators
Published in PET clinics (01-10-2020)“…Total-body PET opens a new diagnostic paradigm with prospects for personalized disease treatment, yet the high cost of the current crystal-based PET technology…”
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Colloquium : Positronium physics and biomedical applications
Published in Reviews of modern physics (01-04-2023)“…Positronium is the simplest bound state, built of an electron and a positron. Studies of positronium in vacuum and its decays in medium tell us about quantum…”
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Microparticles, not only markers but also a therapeutic target in the early stage of diabetic retinopathy and vascular aging
Published in Expert opinion on therapeutic targets (01-07-2012)“…Microparticles (MPs) are small vesicles between 100 and 500 nm, released from different cells including blood, endothelium, smooth muscle, and retina cells…”
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miRNA Signature of Urine Extracellular Vesicles Shows the Involvement of Inflammatory and Apoptotic Processes in Diabetic Chronic Kidney Disease
Published in Pharmaceutical research (01-04-2023)“…Background The aim of this study was to investigate the role of urine-derived extracellular vesicles (uEVs) in diabetic kidney disease (DKD) in patients…”
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Lactadherin: An unappreciated haemostasis regulator and potential therapeutic agent
Published in Vascular pharmacology (01-02-2018)“…Lactadherin is a small (53–66kDa) multifunctional glycoprotein belonging to the secreted extracellular matrix protein family. It has a multi-domain structure…”
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Extracellular Vesicles as Drug Delivery Systems - Methods of Production and Potential Therapeutic Applications
Published in Current pharmaceutical design (01-01-2019)“…Drug delivery systems are created to achieve the desired therapeutic effect of a specific pharmaceutical compound. Numerous drawbacks and side effects such as…”
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3D melanoma spheroid model for the development of positronium biomarkers
Published in Scientific reports (11-05-2023)“…It was recently demonstrated that newly invented positronium imaging may be used for improving cancer diagnostics by providing additional information about…”
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Vascular complications in diabetes: Microparticles and microparticle associated microRNAs as active players
Published in Biochemical and biophysical research communications (25-03-2016)“…The recognition of the importance of diabetes in vascular disease has greatly increased lately. Common risk factors for diabetes-related vascular disease…”
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Hyperglycemia Is Associated With Enhanced Thrombin Formation, Platelet Activation, and Fibrin Clot Resistance to Lysis in Patients With Acute Coronary Syndrome
Published in Diabetes care (01-08-2008)“…OBJECTIVE:--Acute hyperglycemia on admission for acute coronary syndrome worsens the prognosis in patients with and without known diabetes. Postulated…”
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Raman spectroscopy of urinary extracellular vesicles to stratify patients with chronic kidney disease in type 2 diabetes
Published in Nanomedicine (01-01-2022)“…In this study, we verified the hypothesis that Raman signature of urinary extracellular vesicles (UEVs) can be used to stratify patients with diabetes at…”
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Positronium in medicine and biology
Published in Nature reviews physics (01-09-2019)“…In positron emission tomography, as much as 40% of positron annihilation occurs through the production of positronium atoms inside the patient’s body. The…”
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Relationship between carotid intima-media thickness, cytokines, atherosclerosis extent and a two-year cardiovascular risk in patients with arteriosclerosis
Published in Kardiologia polska (2011)“…To investigate the relationship between carotid intima-media thickness (CIMT), biomarkers, atherosclerosis extent and a two-year cardiovascular (CV) event risk…”
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Design and Optimization of a Biosensor Surface Functionalization to Effectively Capture Urinary Extracellular Vesicles
Published in Molecules (Basel, Switzerland) (06-08-2021)“…For this study, we tested and optimized silicon surface functionalization procedures for capturing urinary extracellular vesicles (uEVs). The influence of the…”
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Extracellular vesicles in vascular pathophysiology: beyond their molecular content
Published in Polskie archiwum medycyny wewne̦trznej (19-04-2023)“…Extracellular vesicles (EVs) are released by all cells, both in physiological and pathological conditions. Their molecular charge and composition emerge as…”
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Study of the influence of hyperglycemia on the abundance of amino acids, fatty acids, and selected lipids in extracellular vesicles using TOF-SIMS
Published in Biochemical and biophysical research communications (24-09-2022)“…Time-of-flight secondary ion mass spectrometry (TOF-SIMS) with the Bi3+ liquid metal ion gun was used to investigate the content of lipids and amino acids…”
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