Search Results - "Stępień, Henryk"

High Expression of NEK2 and PIM1, but Not PIM3, Is Linked to an Aggressive Phenotype of Bronchopulmonary Neuroendocrine Neoplasms by Motylewska, Ewelina, Braun, Marcin, Stępień, Henryk

“…Dysregulations of the NEK2 and PIM1-3 kinase signaling axes have been implicated in the pathogenesis of several cancers, including those with a neuroendocrine…”
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IGF1R and MAPK15 Emerge as Potential Targets of Pentabromobenzylisothioureas in Lung Neuroendocrine Neoplasms by Motylewska, Ewelina, Braun, Marcin, Kazimierczuk, Zygmunt, Ławnicka, Hanna, Stępień, Henryk

“…Pentabromobenzylisothioureas are antitumor agents with diverse properties, including the inhibition of MAPK15, IGF1R and PKD1 kinases. Their dysregulation has…”
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Immunohistochemical detection of FSH receptors in pituitary adenomas and adrenal tumors by Pawlikowski, Marek, Pisarek, Hanna, Kubiak, Robert, Jaranowska, Maria, Stępień, Henryk

“…OBJECTIVESFollicle stimulating hormone (FSH) receptors (FSHR) are physiologically expressed in the ovary and testis. It is well known that FSHR are also…”
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Elevated Concentrations of SERPINE2/Protease Nexin-1 and Secretory Leukocyte Protease Inhibitor in the Serum of Patients with Papillary Thyroid Cancer by Lawnicka, Hanna, Komorowski, Jan, Motylewska, Ewelina, Kuzdak, Krzysztof, Brożyna, Mateusz, Stępień, Tomasz, Stępień, Henryk

“…Introduction. SERPINE2 and secretory leukocyte protease inhibitor (SLPI) are proteins with anticoagulant properties which could promote solid tumor growth…”
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Alteration in the serum concentrations of FGF19, FGFR4 and βKlotho in patients with thyroid cancer by Motylewska, Ewelina, Stępień, Tomasz, Borkowska, Magdalena, Kuzdak, Krzysztof, Siejka, Agnieszka, Komorowski, Jan, Stępień, Henryk, Ławnicka, Hanna

“…•Serum concentration of FGF19 was increased in patients with thyroid cancer.•Serum concentration of βKlotho was decreased in patients with thyroid…”
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Long-term impact of vertical banded gastroplasty (VBG) on plasma concentration of leptin, soluble leptin receptor, ghrelin, omentin-1, obestatin, and retinol binding protein 4 (RBP4) in patients with severe obesity by Siejka, Agnieszka, Jankiewicz-Wika, Joanna, Kołomecki, Krzysztof, Cywiński, Jacek, Piestrzeniewicz, Katarzyna, Swiętosławski, Jacek, Stępień, Henryk, Komorowski, Jan

“…•Metabolic syndrome parameters are improved after VBG.•Leptin decreases and soluble leptin receptor and ghrelin increase.•Leptin correlates positively with…”
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Decreased serum level of IL-7 in patients with active Graves’ disease by Motylewska, Ewelina, Nieć, Martyna, Siejka, Agnieszka, Komorowski, Jan, Ławnicka, Hanna, Świętosławski, Jacek, Stępień, Henryk

“…•Serum concentration of IL-7 was decreased in patients with active Graves’ disease.•IL-7 level in patients with Grave’s disease negatively correlated with FT4…”
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Modulation of ghrelin axis influences the growth of colonic and prostatic cancer cells in vitro by Ławnicka, Hanna, Mełeń-Mucha, Gabriela, Motylewska, Ewelina, Mucha, Sławomir, Stępień, Henryk

“…The risk of different cancers seems to be associated with obesity. Moreover, low ghrelin levels observed in obese people may be implicated in cancer…”
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Immunohistochemical detection of follicle stimulating hormone receptor (FSHR) in neuroendocrine tumours by Pawlikowski, Marek, Winczyk, Katarzyna, Stępień, Henryk

“…Follicle stimulating hormone receptors (FSHR) are well known to be expressed in gonads and in gonadal tumours. Recently,their incidence has also been revealed…”
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Elevated serum concentrations of IGF-1 and IGF-1R in patients with thyroid cancers by Lawnicka, Hanna, Motylewska, Ewelina, Borkowska, Magdalena, Kuzdak, Krzysztof, Siejka, Agnieszka, Swietoslawski, Jacek, Stepien, Henryk, Stepien, Tomasz

“…The rising incidence of thyroid cancer observed in the last few decades requires an improvement in diagnostic tools and management techniques for patients with…”
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Reduced plasma level of diazepam-binding inhibitor (DBI) in patients with morbid obesity by Siejka, Agnieszka, Jankiewicz-Wika, Joanna, Stępień, Henryk, Fryczak, Jolanta, Świętosławski, Jacek, Komorowski, Jan

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Immunohistochemical detection of FSH receptors in pituitary adenomas and adrenal tumors by Pawlikowski, Marek, Pisarek, Hanna, Kubiak, Robert, Jaranowska, Maria, Stępień, Henryk

“…Follicle stimulating hormone (FSH) receptors (FSHR) are physiologically expressed in the ovary and testis. It is well known that FSHR are also expressed in…”
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Concentration of angiopoietins 1 and 2 and their receptor Tie-2 in peripheral blood in patients with chronic obstructive pulmonary disease by Kierszniewska-Stępień, Dorota, Pietras, Tadeusz, Ciebiada, Maciej, Górski, Paweł, Stępień, Henryk

“…Both angiopoietins (angiopoietin 1 - Ang-1, angiopoietin 2 - Ang-2) and angiopoietin receptors (Tie) are involved in angiogenesis and vascular remodeling. To…”
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Angiopoietin 1 (Ang-1), angiopoietin 2 (Ang-2) and Tie-2 (a receptor tyrosine kinase) concentrations in peripheral blood of patients with thyroid cancers by Niedźwiecki, Sebastian, Stępień, Tomasz, Kopeć, Krzysztof, Kuzdak, Krzysztof, Komorowski, Jan, Krupiński, Roman, Stępień, Henryk

“…There are limited and conflicting studies investigating the role of the angiopoietin family in human thyroid cancer development and progression. We have…”
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Elevated peripheral blood plasma concentrations of tie-2 and angiopoietin 2 in patients with neuroendocrine tumors by Melen-Mucha, Gabriela, Niedziela, Agata, Mucha, Slawomir, Motylewska, Ewelina, Lawnicka, Hanna, Komorowski, Jan, Stepien, Henryk

“…Gastro-entero-pancreatic/neuroendocrine (NET) tumors are highly vascularized neoplasms. However, our knowledge concerning circulating levels of the angiogenic…”
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Effect of thalidomide affecting VEGF secretion, cell migration, adhesion and capillary tube formation of human endothelial EA.hy 926 cells by Komorowski, Jan, Jerczyńska, Hanna, Siejka, Agnieszka, Barańska, Patrycja, Ławnicka, Hanna, Pawłowska, Zofia, Stępień, Henryk

“…Angiogenesis, new blood vessel formation, is a multistep process, precisely regulated by pro-angiogenic cytokines, which stimulate endothelial cells to…”
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Serum levels of interleukin-1 receptor antagonist (IL-1ra) in thyroid cancer patients by Niedźwiecki, Sebastian, Stępień, Tomasz, Kuzdak, Krzysztof, Stępień, Henryk, Krupiński, Roman, Seehofer, Daniel, Rayes, Nada, Ulrich, Frank

“…Background and aims There is growing evidence that cytokines and their antagonists are important in the pathogenesis of various malignancies. While there are…”
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Effects of nitric oxide synthase inhibition on diethylstilbestrol-induced hyperprolactinaemia and pituitary tumourigenesis in rats by Pawlikowski, Marek, Pisarek, Hanna, Fryczak, Jolanta, Stępień, Henryk

“…The overexpression of nitric oxide synthase (NOS) has been found in tumours, including pituitary adenomas. It has also been found that NOS is overexpressed in…”
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Inhibition of proliferation, VEGF secretion of human neuroendocrine tumor cell line NCI-H727 by an antagonist of growth hormone-releasing hormone (GH-RH) in vitro by Sacewicz, Małgorzata, Ławnicka, Hanna, Siejka, Agnieszka, Stępień, Tomasz, Krupiński, Roman, Komorowski, Jan, Stępień, Henryk

“…Abstract Growth hormone-releasing hormone (GH-RH) can stimulate not only growth hormone (GH) secretion by anterior pituitary gland but also proliferation of…”
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Impact of vertical banded gastroplasty on body weight, insulin resistance, adipocytokine, inflammation and metabolic syndrome markers in morbidly obese patients by Jankiewicz-Wika, Joanna, Kołomecki, Krzysztof, Cywiński, Jacek, Piestrzeniewicz, Katarzyna, Swiętosławski, Jacek, Stępień, Henryk, Komorowski, Jan

“…Diet, exercise, and pharmacological therapy have been shown to be unsatisfactory treatments for severe obesity in the long term. Bariatric surgery is the most…”
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