Search Results - "Stępczyńska, Anna"

Antigen presenting cell-selective drug delivery by glycan-decorated nanocarriers by Frenz, Theresa, Grabski, Elena, Durán, Verónica, Hozsa, Constantin, Stępczyńska, Anna, Furch, Marcus, Gieseler, Robert K., Kalinke, Ulrich

“…[Display omitted] •APC-selective drug delivery suitable for new therapeutic strategies.•Liposomes can deliver decent quantities of defined…”
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Activation and caspase-mediated inhibition of PARP: a molecular switch between fibroblast necrosis and apoptosis in death receptor signaling by Los, Marek, Mozoluk, Malgorzata, Ferrari, Davide, Stepczynska, Anna, Stroh, Christopher, Renz, Andrea, Herceg, Zdenko, Wang, Zhao-Qi, Schulze-Osthoff, Klaus

“…Death ligands not only induce apoptosis but can also trigger necrosis with distinct biochemical and morphological features. We recently showed that in L929…”
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Exonuclease-1 Deletion Impairs DNA Damage Signaling and Prolongs Lifespan of Telomere-Dysfunctional Mice by Schaetzlein, Sonja, Kodandaramireddy, N.R., Ju, Zhenyu, Lechel, Andre, Stepczynska, Anna, Lilli, Dana R., Clark, Alan B., Rudolph, Cornelia, Kuhnel, Florian, Wei, Kaichun, Schlegelberger, Brigitte, Schirmacher, Peter, Kunkel, Thomas A., Greenberg, Roger A., Edelmann, Winfried, Rudolph, K. Lenhard

“…Exonuclease-1 (EXO1) mediates checkpoint induction in response to telomere dysfunction in yeast, but it is unknown whether EXO1 has similar functions in…”
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Staurosporine and conventional anticancer drugs induce overlapping, yet distinct pathways of apoptosis and caspase activation by STEPCZYNSKA, Anna, LAUBER, Kirsten, ENGELS, Ingo H, JANSSEN, Ottmar, KABELITZ, Dieter, WESSELBORG, Sebastian, SCHULZE-OSTHOFF, Klaus

“…Apoptosis can be induced by various stimuli including DNA-damaging anticancer drugs and the protein kinase inhibitor staurosporine. It is generally believed…”
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Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation by Rudolph, K Lenhard, Choudhury, Aaheli Roy, Ju, Zhenyu, Djojosubroto, Meta W, Schienke, Andrea, Lechel, Andre, Schaetzlein, Sonja, Jiang, Hong, Stepczynska, Anna, Wang, Chunfang, Buer, Jan, Lee, Han-Woong, von Zglinicki, Thomas, Ganser, Arnold, Schirmacher, Peter, Nakauchi, Hiromitsu

“…Telomere shortening limits the proliferative lifespan of human cells by activation of DNA damage pathways, including upregulation of the cell cycle inhibitor…”
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Implementation of CE-MS-identified proteome-based biomarker panels in drug development and patient management by Stepczynska, Anna, Schanstra, Joost P, Mischak, Harald

“…The recent advancements in clinical proteomics enabled identification of biomarker panels for a large range of diseases. A number of CE-MS-identified biomarker…”
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Author Correction: Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation by Choudhury, Aaheli Roy, Ju, Zhenyu, Djojosubroto, Meta W., Schienke, Andrea, Lechel, Andre, Schaetzlein, Sonja, Jiang, Hong, Stepczynska, Anna, Wang, Chunfang, Buer, Jan, Lee, Han-Woong, von Zglinicki, Thomas, Ganser, Arnold, Schirmacher, Peter, Nakauchi, Hiromitsu, Rudolph, K. Lenhard

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Exonuclease-1 Deletion Impairs DNA Damage Signaling and Prolongs Lifespan of Telomere-Dysfunctional Mice by Schaetzlein, Sonja, Kodandaramireddy, N.R., Ju, Zhenyu, Lechel, Andre, Stepczynska, Anna, Lilli, Dana R., Clark, Alan B., Rudolph, Cornelia, Kuhnel, Florian, Wei, Kaichun, Schlegelberger, Brigitte, Schirmacher, Peter, Kunkel, Thomas A., Greenberg, Roger A., Edelmann, Winfried, Rudolph, K. Lenhard

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