Search Results - "Stühn, Lara G."

Self‐Assembly Toolbox of Tailored Supramolecular Architectures Based on an Amphiphilic Protein Library by Schreiber, Andreas, Stühn, Lara G., Huber, Matthias C., Geissinger, Süreyya E., Rao, Ashit, Schiller, Stefan M.

“…The molecular structuring of complex architectures and the enclosure of space are essential requirements for technical and living systems. Self‐assembly of…”
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Adjustable Bioorthogonal Conjugation Platform for Protein Studies in Live Cells Based on Artificial Compartments by Geissinger, Süreyya E, Schreiber, Andreas, Huber, Matthias C, Stühn, Lara G, Schiller, Stefan M

“…The investigation of complex biological processes in vivo often requires defined multiple bioconjugation and positioning of functional entities on 3D…”
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Programming protein phase-separation employing a modular library of intrinsically disordered precision block copolymer-like proteins creating dynamic cytoplasmatic compartmentalization by Huber, Matthias C., Schreiber, Andreas, Stühn, Lara G., Schiller, Stefan M.

“…The control of supramolecular complexes in living systems at the molecular level is an important goal in life-sciences. Spatiotemporal organization of…”
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Dynamic Structural Changes and Thermodynamics in Phase Separation Processes of an Intrinsically Disordered–Ordered Protein Model by Lüdeke, Steffen, Lohner, Philipp, Stühn, Lara G., Betschart, Martin U., Huber, Matthias C., Schreiber, Andreas, Schiller, Stefan M.

“…Elastin‐like proteins (ELPs) are biologically important proteins and models for intrinsically disordered proteins (IDPs) and dynamic structural transitions…”
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Diagnostic genome sequencing improves diagnostic yield: a prospective single-centre study in 1000 patients with inherited eye diseases by Weisschuh, Nicole, Mazzola, Pascale, Zuleger, Theresia, Schaeferhoff, Karin, Kühlewein, Laura, Kortüm, Friederike, Witt, Dennis, Liebmann, Alexandra, Falb, Ruth, Pohl, Lisa, Reith, Milda, Stühn, Lara G, Bertrand, Miriam, Müller, Amelie, Casadei, Nicolas, Kelemen, Olga, Kelbsch, Carina, Kernstock, Christoph, Richter, Paul, Sadler, Francoise, Demidov, German, Schütz, Leon, Admard, Jakob, Sturm, Marc, Grasshoff, Ute, Tonagel, Felix, Heinrich, Tilman, Nasser, Fadi, Wissinger, Bernd, Ossowski, Stephan, Kohl, Susanne, Riess, Olaf, Stingl, Katarina, Haack, Tobias B

“…Genome sequencing (GS) is expected to reduce the diagnostic gap in rare disease genetics. We aimed to evaluate a scalable framework for genome-based analyses…”
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Episignature analysis of moderate effects and mosaics by Oexle, Konrad, Zech, Michael, Stühn, Lara G, Siegert, Sandy, Brunet, Theresa, Schmidt, Wolfgang M, Wagner, Matias, Schmidt, Axel, Engels, Hartmut, Tilch, Erik, Monestier, Olivier, Destrėe, Anne, Hanker, Britta, Boesch, Sylvia, Jech, Robert, Berutti, Riccardo, Kaiser, Frank, Haslinger, Bernhard, Haack, Tobias B, Garavaglia, Barbara, Krawitz, Peter, Winkelmann, Juliane, Mirza-Schreiber, Nazanin

“…DNA methylation classifiers ("episignatures") help to determine the pathogenicity of variants of uncertain significance (VUS). However, their sensitivity is…”
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Multiplexed antibody detection from blood sera by immobilization of in vitro expressed antigens and label-free readout via imaging reflectometric interferometry (iRIf) by Bender, Julian, Bognar, Sabine, Camagna, Maurizio, Donauer, Julia A.M., Eble, Julian W., Emig, Ramona, Fischer, Sabrina, Jesser, Rabea, Keilholz, Luisa, Kokotek, Daniel M.U., Neumann, Julika, Nicklaus, Simon, Oude Weernink, Ricardo R.Q.P.T., Stühn, Lara G., Wössner, Nathalie, Krämer, Stefan D., Schwenk, Philipp, Gensch, Nicole, Roth, Günter, Ulbrich, Maximilian H.

“…The detection of antibodies from blood sera is crucial for diagnostic purposes. Miniaturized protein assays in combination with microfluidic setups hold great…”
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Dynamische Strukturänderung und Thermodynamik von Phasentrennprozessen eines Proteinmodells mit intrinsisch ungeordneter/geordneter Struktur by Lüdeke, Steffen, Lohner, Philipp, Stühn, Lara G., Betschart, Martin U., Huber, Matthias C., Schreiber, Andreas, Schiller, Stefan M.

“…Elastin‐artige Proteine (ELPs) haben neben ihrer biologischen Funktion auch Bedeutung als Modelle für intrinsisch ungeordnete Proteine und dynamische…”
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Heterozygous loss-of-function SMC3 variants are associated with variable growth and developmental features by Ansari, Morad, Faour, Kamli N.W., Shimamura, Akiko, Grimes, Graeme, Kao, Emeline M., Denhoff, Erica R., Blatnik, Ana, Ben-Isvy, Daniel, Wang, Lily, Helm, Benjamin M., Firth, Helen, Breman, Amy M., Bijlsma, Emilia K., Iwata-Otsubo, Aiko, de Ravel, Thomy J.L., Fusaro, Vincent, Fryer, Alan, Nykamp, Keith, Stühn, Lara G., Haack, Tobias B., Korenke, G. Christoph, Constantinou, Panayiotis, Bujakowska, Kinga M., Low, Karen J., Place, Emily, Humberson, Jennifer, Napier, Melanie P., Hoffman, Jessica, Juusola, Jane, Deardorff, Matthew A., Shao, Wanqing, Rockowitz, Shira, Krantz, Ian, Kaur, Maninder, Raible, Sarah, Dortenzio, Victoria, Kliesch, Sabine, Singer-Berk, Moriel, Groopman, Emily, DiTroia, Stephanie, Ballal, Sonia, Srivastava, Siddharth, Rothfelder, Kathrin, Biskup, Saskia, Rzasa, Jessica, Kerkhof, Jennifer, McConkey, Haley, Sadikovic, Bekim, Hilton, Sarah, Banka, Siddharth, Tüttelmann, Frank, Conrad, Donald F., O’Donnell-Luria, Anne, Talkowski, Michael E., FitzPatrick, David R., Boone, Philip M.

“…Heterozygous missense variants and in-frame indels in SMC3 are a cause of Cornelia de Lange syndrome (CdLS), marked by intellectual disability, growth…”
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Hemizygous variants in protein phosphatase 1 regulatory subunit 3F (PPP1R3F) are associated with a neurodevelopmental disorder characterized by developmental delay, intellectual disability and autistic features by Liu, Zhigang, Xin, Baozhong, Smith, Iris N, Sency, Valerie, Szekely, Julia, Alkelai, Anna, Shuldiner, Alan, Efthymiou, Stephanie, Rajabi, Farrah, Coury, Stephanie, Brownstein, Catherine A, Rudnik-Schöneborn, Sabine, Bruel, Ange-Line, Thevenon, Julien, Zeidler, Shimriet, Jayakar, Parul, Schmidt, Axel, Cremer, Kirsten, Engels, Hartmut, Peters, Sophia O, Zaki, Maha S, Duan, Ruizhi, Zhu, Changlian, Xu, Yiran, Gao, Chao, Sepulveda-Morales, Tania, Maroofian, Reza, Alkhawaja, Issam A, Khawaja, Mariam, Alhalasah, Hunaida, Houlden, Henry, Madden, Jill A, Turchetti, Valentina, Marafi, Dana, Agrawal, Pankaj B, Schatz, Ulrich, Rotenberg, Ari, Rotenberg, Joshua, Mancini, Grazia M S, Bakhtiari, Somayeh, Kruer, Michael, Thiffault, Isabelle, Hirsch, Steffen, Hempel, Maja, Stühn, Lara G, Haack, Tobias B, Posey, Jennifer E, Lupski, James R, Lee, Hyunpil, Sarn, Nicholas B, Eng, Charis, Gonzaga-Jauregui, Claudia, Zhang, Bin, Wang, Heng

“…Abstract Protein phosphatase 1 regulatory subunit 3F (PPP1R3F) is a member of the glycogen targeting subunits (GTSs), which belong to the large group of…”
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