Search Results - "Stühmer, W"
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1
Role of voltage-gated potassium channels in cancer
Published in The Journal of membrane biology (01-06-2005)“…Ion channels are being associated with a growing number of diseases including cancer. This overview summarizes data on voltage-gated potassium channels (VGKCs)…”
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The role of the I sK protein in the specific pharmacological properties of the I Ks channel complex
Published in British journal of pharmacology (05-02-2009)“…I Ks channels are composed of I sK and KvLQT1 subunits and underly the slowly activating, voltage‐dependent I Ks conductance in heart. Although it appears…”
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3
Eag1 potassium channel immunohistochemistry in the CNS of adult rat and selected regions of human brain
Published in Neuroscience (26-08-2008)“…Eag1 (K V10.1) is the founding member of an evolutionarily conserved superfamily of voltage-gated K + channels. In rats and humans Eag1 is preferentially…”
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4
Tracking chromaffin granules on their way through the actin cortex
Published in European biophysics journal (01-01-2000)“…Quantitative time-lapse evanescent-wave imaging of individual fluorescently labelled chromaffin granules was used for kinetic analysis of granule trafficking…”
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5
Ether-à-go-go 1 (Eag1) Potassium Channel Expression in Dopaminergic Neurons of Basal Ganglia is Modulated by 6-Hydroxydopamine Lesion
Published in Neurotoxicity research (01-04-2012)“…The ether à go - go (Eag) gene encodes the voltage-gated potassium (K + ) ion channel Kv10.1, whose function still remains unknown. As dopamine may directly…”
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IRK(1-3) and GIRK(1-4) Inwardly Rectifying K+ Channel mRNAs Are Differentially Expressed in the Adult Rat Brain
Published in The Journal of neuroscience (01-06-1996)“…Molecular cloning together with functional characterization has shown that the newly identified family of inwardly rectifying K+ channels consists of several…”
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7
Electrophysiological recording from Xenopus oocytes
Published in Methods in enzymology (1992)Get more information
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8
Hippocampal ether-à-go-go1 potassium channels blockade: effects in the startle reflex and prepulse inhibition
Published in Neuroscience letters (24-01-2014)“…Recently, our group described the ether-à-go-go1(Eag1) voltage-gated potassium (K(+)) channel (Kv10.1) expression in the dopaminergic cells indicating that…”
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9
Electrophysiologic recordings from Xenopus oocytes
Published in Methods in enzymology (1998)Get more information
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10
Extracellular K+Specifically Modulates a Rat Brain K+Channel
Published in Proceedings of the National Academy of Sciences - PNAS (15-03-1992)“…Extracellular potassium concentration is actively maintained within narrow limits in all higher organisms. Slight variations in extracellular potassium levels…”
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11
Eag1, Eag2, and SK3 potassium channel expression in the rat hippocampus after global transient brain ischemia
Published in Journal of neuroscience research (01-03-2012)“…Transient global brain ischemia causes delayed neuronal death in the hippocampus that has been associated with impairments in hippocampus‐dependent brain…”
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12
P2X4: An ATP-Activated Ionotropic Receptor Cloned from Rat Brain
Published in Proceedings of the National Academy of Sciences - PNAS (16-04-1996)“…Extracellular ATP exerts pronounced biological actions in virtually every organ or tissue that has been studied. In the central and peripheral nervous system,…”
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13
Depletion of InsP3 stores activates a Ca2+ and K+ current by means of a phosphatase and a diffusible messenger
Published in Nature (London) (26-08-1993)“…In non-excitable cells, release of Ca2+ from the inositol 1,4,5-trisphosphate (InsP3)-sensitive store can activate Ca2+ entry. Very little is known about the…”
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14
Cloned ligand-gated channels activated by extracellular ATP (P2X receptors)
Published in The Journal of membrane biology (15-11-1997)Get full text
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15
The last few milliseconds in the life of a secretory granule. Docking, dynamics and fusion visualized by total internal reflection fluorescence microscopy (TIRFM)
Published in European biophysics journal (01-01-1998)“…We have monitored single vesicles (granules) in bovine adrenal chromaffin cells using an optical sectioning technique, total internal reflection fluorescence…”
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16
Calcium channel characteristics conferred on the sodium channel by single mutations
Published in Nature (London) (02-04-1992)“…The sodium channel, one of the family of structurally homologous voltage-gated ion channels, differs from other members, such as the calcium and the potassium…”
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17
Cell Cycle-Related Changes in the Conducting Properties of r-Eag K+Channels
Published in The Journal of cell biology (02-11-1998)“…Release from arrest in G2 phase of the cell cycle causes profound changes in rat ether-à-go-go (r-eag) K+channels heterologously expressed in Xenopus oocytes…”
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18
Interaction of secretory organelles with the membrane
Published in The Journal of membrane biology (01-12-2000)Get full text
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19
Eag 1, Eag 2 and Kcnn3 gene brain expression of isolated reared rats
Published in Genes, brain and behavior (01-11-2010)“…The Eag1 and Eag2, voltage‐dependent potassium channels, and the small‐conductance calcium‐activated potassium channel (Kcnn3) are highly expressed in limbic…”
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20
Alternative splicing of the human Shaker K+ channel beta 1 gene and functional expression of the beta 2 gene product
Published in FEBS letters (14-08-1995)“…Mammalian voltage-activated Shaker K+ channels associate with at least three cytoplasmic proteins: Kv beta 1, Kv beta 2 and Kv beta 3. These beta subunits…”
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