Search Results - "Stévenin, Virginie"

The phosphoinositide coincidence detector Phafin2 promotes macropinocytosis by coordinating actin organisation at forming macropinosomes by Schink, Kay Oliver, Tan, Kia Wee, Spangenberg, Hélène, Martorana, Domenica, Sneeggen, Marte, Stévenin, Virginie, Enninga, Jost, Campsteijn, Coen, Raiborg, Camilla, Stenmark, Harald

“…Uptake of large volumes of extracellular fluid by actin-dependent macropinocytosis has an important role in infection, immunity and cancer development. A key…”
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Shigella hijacks the exocyst to cluster macropinosomes for efficient vacuolar escape by Chang, Yuen-Yan, Stévenin, Virginie, Duchateau, Magalie, Giai Gianetto, Quentin, Hourdel, Veronique, Rodrigues, Cristina Dias, Matondo, Mariette, Reiling, Norbert, Enninga, Jost, Monack, Denise M

“…Shigella flexneri invades host cells by entering within a bacteria-containing vacuole (BCV). In order to establish its niche in the host cytosol, the bacterium…”
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Dynamic Growth and Shrinkage of the Salmonella-Containing Vacuole Determines the Intracellular Pathogen Niche by Stévenin, Virginie, Chang, Yuen-Yan, Le Toquin, Yoann, Duchateau, Magalie, Gianetto, Quentin Giai, Luk, Chak Hon, Salles, Audrey, Sohst, Victoria, Matondo, Mariette, Reiling, Norbert, Enninga, Jost

“…Salmonella is a human and animal pathogen that causes gastro-enteric diseases. The key to Salmonella infection is its entry into intestinal epithelial cells,…”
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Purification of infection-associated macropinosomes by magnetic isolation for proteomic characterization by Stévenin, Virginie, Giai Gianetto, Quentin, Duchateau, Magalie, Matondo, Mariette, Enninga, Jost, Chang, Yuen-Yan

“…Macropinocytosis refers to the nonselective uptake of extracellular molecules into many different types of eukaryotic cells within large fluid-filled vesicles…”
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FHOD1 Is Needed for Directed Forces and Adhesion Maturation during Cell Spreading and Migration by Iskratsch, Thomas, Yu, Cheng-Han, Mathur, Anurag, Liu, Shuaimin, Stévenin, Virginie, Dwyer, Joseph, Hone, James, Ehler, Elisabeth, Sheetz, Michael

“…Matrix adhesions provide critical signals for cell growth or differentiation. They form through a number of distinct steps that follow integrin binding to…”
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Multi-omics analyses of cancer-linked clinical salmonellae reveal bacterial-induced host metabolic shift and mTOR-dependent cell transformation by Stévenin, Virginie, Coipan, Claudia E., Duijster, Janneke W., van Elsland, Daphne M., Voogd, Linda, Bigey, Lise, van Hoek, Angela H.A.M., Wijnands, Lucas M., Janssen, Lennert, Akkermans, Jimmy J.L.L., Neefjes-Borst, Andra, Franz, Eelco, Mughini-Gras, Lapo, Neefjes, Jacques

“…Salmonellae are associated epidemiologically and experimentally with colon cancer. To understand how Salmonella induces cell transformation, we performed…”
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The entry of Salmonella in a distinct tight compartment revealed at high temporal and ultrastructural resolution by Fredlund, Jennifer, Santos, José Carlos, Stévenin, Virginie, Weiner, Allon, Latour‐Lambert, Patricia, Rechav, Katya, Mallet, Adeline, Krijnse‐Locker, Jacomine, Elbaum, Michael, Enninga, Jost

“…Salmonella enterica induces membrane ruffling and genesis of macropinosomes during its interactions with epithelial cells. This is achieved through the type…”
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Repetitive non-typhoidal Salmonella exposure is an environmental risk factor for colon cancer and tumor growth by van Elsland, Daphne M., Duijster, Janneke W., Zhang, Jilei, Stévenin, Virginie, Zhang, Yongguo, Zha, Lang, Xia, Yinglin, Franz, Eelco, Sun, Jun, Mughini-Gras, Lapo, Neefjes, Jacques

“…During infection, Salmonella hijacks essential host signaling pathways. These molecular manipulations disrupt cellular integrity and may induce oncogenic…”
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Ubiquitin and its relatives as wizards of the endolysosomal system by Berlin, Ilana, Sapmaz, Aysegul, Stévenin, Virginie, Neefjes, Jacques

“…The endolysosomal system comprises a dynamic constellation of vesicles working together to sense and interpret environmental cues and facilitate homeostasis…”
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Soft agar colony formation assay to quantify mouse embryonic fibroblast transformation after Salmonella infection by Stévenin, Virginie, Neefjes, Jacques

“…Links between bacterial infections and cancer are actively investigated. Cost-effective assays to quantify bacterial oncogenic potential can shed new light on…”
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New methods to decrypt emerging macropinosome functions during the host–pathogen crosstalk by Chang, Yuen‐Yan, Enninga, Jost, Stévenin, Virginie

“…Large volumes of liquid and other materials from the extracellular environment are internalised by eukaryotic cells via an endocytic process called…”
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Cellular Imaging of Intracellular Bacterial Pathogens by Stévenin, Virginie, Enninga, Jost

“…The spatial dimensions of host cells and bacterial microbes are perfectly suited to being studied by microscopy techniques. Therefore, cellular imaging has…”
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Identification of Parameters of Host Cell Vulnerability during Salmonella Infection by Quantitative Image Analysis and Modeling by Voznica, Jakub, Gardella, Christophe, Belotserkovsky, Ilia, Dufour, Alexandre, Enninga, Jost, Stévenin, Virginie

“…targets and enters epithelial cells at permissive entry sites: some cells are more likely to be infected than others. However, the parameters that lead to host…”
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High-throughput Microscopic Analysis of Salmonella Invasion of Host Cells by Voznica, Jakub, Enninga, Jost, Stévenin, Virginie

“…is a Gram-negative bacterium causing a gastro-enteric disease called salmonellosis. During the first phase of infection, uses its flagella to swim near the…”
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FHOD1 at Early Integrin Adhesions Drives Cell Spreading by Iskratsch, Thomas, Yu, Cheng-Han, Mathur, Anurag, Liu, Shuaimin, Stévenin, Virginie, Dwyer, Joseph, Hone, James, Ehler, Elisabeth, Sheetz, Michael

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