Search Results - "Stéphanou, A."

A computational model of cell migration coupling the growth of focal adhesions with oscillatory cell protrusions by Stéphanou, Angélique, Mylona, Eleni, Chaplain, Mark, Tracqui, Philippe

“…Cell migration is a highly integrated process where actin turnover, actomyosin contractility, and adhesion dynamics are all closely linked. In this paper, we…”
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Mathematical modelling of flow in 2D and 3D vascular networks: Applications to anti-angiogenic and chemotherapeutic drug strategies by Stéphanou, A., McDougall, S.R., Anderson, A.R.A., Chaplain, M.A.J.

“…The aim of this paper is to investigate the conditions required to optimize the amount of chemotherapeutic drug absorbed by a solid tumour through a network of…”
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Can major breakthroughs in cancer be achieved through theoretical models?: Comment on “Improving cancer treatments via dynamical biophysical models” by M. Kuznetsov, J. Clairambault and V. Volpert by Stéphanou, A.

“…The review by Kuznetsov, Clairambault and Volpert [1] presents a state-of-the-art in mathematical oncology focusing on dynamical biophysical models and their…”
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Can major breakthroughs in cancer be achieved through theoretical models? by Stéphanou, A.

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A mathematical model for the dynamics of large membrane deformations of isolated fibroblasts by Stéphanou, A., Chaplain, M.A.J., Tracqui, P.

“…In this paper we develop and extend a previous model of cell deformations, initially proposed to describe the dynamical behaviour of round-shaped cells such as…”
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How tumour-induced vascular changes alter angiogenesis: Insights from a computational model by Stéphanou, A., Lesart, A.C., Deverchère, J., Juhem, A., Popov, A., Estève, F.

“…A computational model was developed to describe experimentally observed vascular changes induced by the introduction of a tumour on a mouse equipped with a…”
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A mathematical model of HiF-1α-mediated response to hypoxia on the G1/S transition by Bedessem, B., Stéphanou, A.

“…•The model describes the G1/S transition under hypoxia through the HiF-1α pathway.•The inhibition of the cyclin D by HiF-1α can affect the cell cycle.•A link…”
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Role of STAT‐1 and STAT‐3 in ischaemia/reperfusion injury by Stephanou, A.

“…Ischaemia/reperfusion (I/R) injury results in the death of irreplaceable cardiac myocytes by a programme cell death or apoptosis. The signal transducers and…”
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STAT1 deficiency in the heart protects against myocardial infarction by enhancing autophagy by McCormick, J., Suleman, N., Scarabelli, T.M., Knight, R.A., Latchman, D.S., Stephanou, A.

“…Previous studies have shown that the transcription factor signal transducer and activator of transcription 1 (STAT1) activation is increased in primary cardiac…”
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A minimal biomechanical model for random cell migration by Manifacier, I., Chauvière, A., Verdier, C., Chagnon, G., Cheddadi, I., Glade, N., Stéphanou, A.

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Mathematical modelling of the influence of blood rheological properties upon adaptative tumour-induced angiogenesis by Stéphanou, A., McDougall, S.R., Anderson, A.R.A., Chaplain, M.A.J.

“…In this paper, we present a theoretical investigation of the influence of blood flow through a tumour-induced capillary network, whereby the vascular…”
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Opposing actions of STAT-1 and STAT-3 by Stephanou, A., Latchman, D. S.

“…The signal transducers and activators of transcription (STATs) are a family of transcription factors, which were originally identified on the basis of their…”
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A mathematical model of HiF-1-mediated response to hypoxia on the G1/S transition by Bedessem, B., Stéphanou, A.

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South African pharmacists impact on antibiotic hang-time in the intensive care unit patients by Stephanou, A, van den Bergh, D, Goff, D, Beukes, C.C

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Service quality perceptions of campus-based food outlets by Swanepoel, Rochelle, Eresia-Eke, Chukuakadibia E., Stephanou, Mon A.

“…Orientation: In a competitive retail business environment, the essence of service quality is invariably amplified. Within a university context, the same…”
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Corrigendum : service quality perceptions of campus-based food outlets by Stephanou, Monique A., Eresia-Eke, Chukuakadibia E., Swanepoel, Rochelle

“…In the author list of this article initially published, Monique A. Stephanou’s first name was unintentionally misprinted as ‘Mon’. The correct first name is…”
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Opposing actions of STAT-1 and STAT-3 on the Bcl-2 and Bcl-x promoters by Stephanou, A, Brar, B K, Knight, R A, Latchman, D S

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The rigidity in fibrin gels as a contributing factor to the dynamics of in vitro vascular cord formation by Stéphanou, A., Meskaoui, G., Vailhé, B., Tracqui, P.

“…While the formation of vascular cords in in vitro angiogenesis assay is commonly used to test the angiogenic properties of many molecular or cellular…”
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KATP channel gene expression is induced by urocortin and mediates its cardioprotective effect by LAWRENCE, K. M, CHANALARIS, A, KNIGHT, R. A, LATCHMAN, D. S, SCARABELLI, T, HUBANK, M, PASINI, E, TOWNSEND, P. A, COMINI, L, FERRARI, R, TINKER, A, STEPHANOU, A

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Urocortin increases the expression of heat shock protein 90 in rat cardiac myocytes in a MEK1/2-dependent manner by Brar, BK, Railson, J, Stephanou, A, Knight, RA, Latchman, DS

“…We have previously demonstrated that urocortin protects cultured cardiac myocytes from ischaemic and reoxygenation injury and decreases the infarct size in the…”
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