Search Results - "Stéhelin, Dominique"

Ectopic expression of H-1 parvovirus NS1 protein induces alterations in actin filaments and cell death in human normal MRC-5 and transformed MRC-5 SV2 cells by Wizla, Pierre, Begue, Agnès, Loison, Ingrid, Richard, Audrey, Caillet-Fauquet, Perrine, Stéhelin, Dominique

“…When grown in human cell lines, oncolytic H-1 parvovirus (H-1PV) replication preferentially occurs in transformed cells, which ultimately die upon infection…”
Get full text

ETS-1 Transcription Factor Binds Cooperatively to the Palindromic Head to Head ETS-binding Sites of the Stromelysin-1 Promoter by Counteracting Autoinhibition by Baillat, David, Bègue, Agnès, Stéhelin, Dominique, Aumercier, Marc

“…Stromelysin-1 (matrix metalloproteinase-3) is a member of the matrix metalloproteinase family. Regulation of its gene expression is critical for tissue…”
Get full text

Molecular phylogeny of the ETS gene family by LAUDET, V, HÄNNI, C, STEHELIN, D, DUTERQUE-COQUILLAUD, M

“…We have constructed a molecular phylogeny of the ETS gene family. By distance and parsimony analysis of the ETS conserved domains we show that the family…”
Get full text

The H19 TATA-less promoter is efficiently repressed by wild-type tumor suppressor gene product p53 by DUGIMONT, T, MONTPELLIER, C, ADRIAENSSENS, E, LOTTIN, S, DUMONT, L, IOTSOVA, V, LAGROU, C, STEHELIN, D, COLL, J, CURGY, J.-J

“…The developmentally regulated H19 gene displays several remarkable properties: expression of an apparently non-translated mRNA, genomic imprinting (maternal…”
Get full text

A revised and complete map of the chicken c-mil/raf-1 locus by BRUMMER, Tilman, STEHELIN, Dominique, MISAWA, Yukiko, RETH, Michael

“…The chicken c-mil/raf-1 gene (formerly also known as c-mht) was originally identified in the search for the cellular counterpart to the v-mil oncogene of the…”
Get full text

Ligand Binding was Acquired during Evolution of Nuclear Receptors by Escriva, Hector, Safi, Rachid, Hänni, Catherine, Langlois, Marie-Claire, Saumitou-Laprade, Pierre, Stehelin, Dominique, Capron, André, Pierce, Raymond, Laudet, Vincent

“…The nuclear receptor (NR) superfamily comprises, in addition to ligand-activated transcription factors, members for which no ligand has been identified to…”
Get full text

Targeting of PML/RAR Is Lethal to Retinoic Acid–Resistant Promyelocytic Leukemia Cells by Nason-Burchenal, Kathryn, Allopenna, Janet, Bègue, Agnes, Stéhelin, Dominique, Dmitrovsky, Ethan, Martin, Patrick

“…Acute promyelocytic leukemia (APL) cells, containing the t(15;17) rearrangement, express the fusion protein, PML/RAR. Clinically, patients respond to…”
Get full text

The relationship between cell proliferation and the transcription of the nuclear oncogenes c-myc, c-myb and c-ets-1 during feather morphogenesis in the chick embryo by DESBIENS, X, QUEVA, C, JAFFREDO, T, STEHELIN, D, VANDENBUNDER, B

“…We have described the expression of three nuclear protooncogenes, c-myc, c-myb and c-ets-1 during feather morphogenesis in the chick embryo. In parallel with…”
Get full text

Ancestry and diversity of the HMG box superfamily by Laudet, V, Stehelin, D, Clevers, H

“…The HMG box is a novel type of DNA-binding domain found in a diverse group of proteins. The HMG box superfamily comprises a.o. the High Mobility Group proteins…”
Get full text

Increased T-cell apoptosis and terminal B-cell differentiation induced by inactivation of the Ets-1 proto-oncogene by Bories, Jean-Christophe, Willerford, Dennis M, Grévin, Delphine, Davidson, Laurie, Camus, Anne, Martin, Patrick, Stéhelin, Dominique, Alt, Frederick W

“…The Ets-1 proto-oncogene is a member of a transcription factor family characterized by homology to the v-ets oncogene. In adult mice, Ets-1 is expressed…”
Get full text

Erg proteins, transcription factors of the Ets family, form homo, heterodimers and ternary complexes via two distinct domains by CARRERE, S, VERGER, A, FLOURENS, A, STEHELIN, D, DUTERQUE-COQUILLAUD, M

“…The ets genes family encodes a group of proteins which function as transcription factors under physiological conditions. We report here that the Erg proteins,…”
Get full text

Thec-ets-1Proto-oncogene Is a New Early-Response Gene Differentially Regulated by Cytokines and Growth Factors in Human Fibroblasts by Gilles, Frédéric, Raes, Marie-Berthe, Stéhelin, Dominique, Vandenbunder, Bernard, Fafeur, Véronique

“…In various invasive human tumors,c-ets-1mRNA was found to be selectively expressed in stromal fibroblasts. We have now investigated the possibility that…”
Get full text

A Functional Rev-erbα Responsive Element Located in the Human Rev-erbα Promoter Mediates a Repressing Activity by Adelmant, Guillaume, Bègue, Agnès, Stéhelin, Dominique, Laudet, Vincent

“…Rev-erbα belongs to the nuclear receptor superfamily, which contains receptors for steroids, thyroid hormones, retinoic acid, and vitamin D, as well as…”
Get full text

Characterization and functional analysis of the p42Ets-1 variant of the mouse Ets-1 transcription factor by LIONNETON, Frédéric, LELIEVRE, Etienne, BAILLAT, David, STEHELIN, Dominique, SONCIN, Fabrice

“…We have identified the mouse exon VII splice variant of the Ets-1 transcription factor. The variant is expressed in all cell lines which express ets-1, at…”
Get full text

A cAMP Response Element and an Ets Motif Are Involved in the Transcriptional Regulation of flt-1 Tyrosine Kinase (Vascular Endothelial Growth Factor Receptor 1) Gene by Wakiya, Kenji, Begue, Agnès, Stehelin, Dominique, Shibuya, Masabumi

“…The flt-1 gene encodes a transmembrane tyrosine kinase, Flt-1, a receptor for vascular endothelial growth factor. The expression of flt-1 gene is restricted to…”
Get full text

Molecular Cloning and Characterization of the Mouse E2F6 Gene by Kherrouche, Zoulika, Begue, Agnès, Stehelin, Dominique, Monté, Didier

“…E2F6 is the most recently identified member of the E2F family. In this study, the murine E2F6 gene was cloned and found to consist of eight exons. Analysis of…”
Get full text

Expression of interstitial collagenase is restricted to skeletal tissue during mouse embryogenesis by Mattot, V, Raes, M B, Henriet, P, Eeckhout, Y, Stehelin, D, Vandenbunder, B, Desbiens, X

“…Collagenases are thought to be involved in physiological and pathological processes that require extracellular matrix remodeling. Using the in situ…”
Get full text

Mutual repression of transcriptional activation between the ETS-related factor ERG and estrogen receptor by VLAEMINCK-GUILLEM, Virginie, VANACKER, Jean-Marc, VERGER, Alexis, TOMAVO, Nathalie, STEHELIN, Dominique, LAUDET, Vincent, DUTERQUE-COQUILLAUD, Martine

“…Transcription factors are known to interact with each other to modulate their transcriptional activity. In this study, we found that the transcriptional…”
Get full text

Erg, an Ets-family member, differentially regulates human collagenase1 (MMP1) and stromelysin1 (MMP3) gene expression by physically interacting with the Fos/Jun complex by Butticè, G, Duterque-Coquillaud, M, Basuyaux, J P, Carrère, S, Kurkinen, M, Stéhelin, D

“…Collagenase1 (MMP1) and stromelysin1 (MMP3) are extracellular proteolytic enzymes that degrade connective tissue macromolecules and basement membranes. Both…”
Get more information

Evolution of the nuclear receptor gene superfamily by Laudet, V, Hanni, C, Coll, J, Catzeflis, F, Stehelin, D

“…Nuclear receptor genes represent a large family of genes encoding receptors for various hydrophobic ligands such as steroids, vitamin D, retinoic acid and…”
Get full text