Search Results - "Ssenkusu, John M."
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Acute kidney injury is associated with impaired cognition and chronic kidney disease in a prospective cohort of children with severe malaria
Published in BMC medicine (21-05-2019)“…Acute kidney injury (AKI) is a recognized complication of pediatric severe malaria, but its long-term consequences are unknown. Ugandan children with cerebral…”
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Complete sources of cluster variation on the risk of under-five malaria in Uganda: a multilevel-weighted mixed effects logistic regression model approach
Published in Malaria journal (19-10-2023)“…Abstract Background Malaria, a major cause of mortality worldwide is linked to a web of determinants ranging from individual to contextual factors. This calls…”
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Acute kidney injury in Ugandan children with severe malaria is associated with long-term behavioral problems
Published in PloS one (17-12-2019)“…Acute kidney injury (AKI) is a risk factor for neurocognitive impairment in severe malaria (SM), but the impact of AKI on long-term behavioral outcomes…”
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Effect of four or more antenatal care visits on facility delivery and early postnatal care services utilization in Uganda: a propensity score matched analysis
Published in BMC pregnancy and childbirth (03-01-2022)“…Maternal mortality remains a global public health issue, more predominantly in developing countries, and is associated with poor maternal health services…”
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Xanthine oxidase levels and immune dysregulation are independently associated with anemia in Plasmodium falciparum malaria
Published in Scientific reports (07-09-2023)“…Severe anemia is an important contributor to mortality in children with severe malaria. Anemia in malaria is a multi-factorial complication, since…”
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HIV infection among men who have sex with men in Kampala, Uganda--a respondent driven sampling survey
Published in PloS one (31-05-2012)“…Uganda's generalized HIV epidemic is well described, including an estimated adult male HIV prevalence in Kampala of 4.5%, but no data are available on the…”
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Neurodevelopmental performance among pre-schoolers treated for severe anaemia at Lira Regional Referral Hospital, Uganda
Published in PloS one (04-11-2020)“…Severe anaemia is a common clinical problem among young children in sub-Saharan Africa. However, the effect of severe anaemia on neurodevelopment of these…”
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Parenteral artemisinins are associated with reduced mortality and neurologic deficits and improved long-term behavioral outcomes in children with severe malaria
Published in BMC medicine (28-07-2021)“…In 2011, the World Health Organization recommended injectable artesunate as the first-line therapy for severe malaria (SM) due to its superiority in reducing…”
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Plasma angiopoietin-2 is associated with age-related deficits in cognitive sub-scales in Ugandan children following severe malaria
Published in Malaria journal (06-01-2021)“…Elevated angiopoietin-2 (Angpt-2) concentrations are associated with worse overall neurocognitive function in severe malaria survivors, but the specific…”
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10
Acute kidney injury, persistent kidney disease, and post-discharge morbidity and mortality in severe malaria in children: A prospective cohort study
Published in EClinicalMedicine (01-02-2022)“…Globally, 85% of acute kidney injury (AKI) cases occur in low-and-middle-income countries. There is limited information on persistent kidney disease (acute…”
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Methods to estimate baseline creatinine and define acute kidney injury in lean Ugandan children with severe malaria: a prospective cohort study
Published in BMC nephrology (29-09-2020)“…Acute kidney injury (AKI) is increasingly recognized as a consequential clinical complication in children with severe malaria. However, approaches to estimate…”
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Use of the creating opportunities for parent empowerment programme to decrease mental health problems in Ugandan children surviving severe malaria: a randomized controlled trial
Published in Malaria journal (13-06-2021)“…Abstract Background Severe malaria is associated with long-term mental health problems in Ugandan children. This study investigated the effect of a behavioural…”
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How interventions to maintain services during the COVID-19 pandemic strengthened systems for delivery of maternal and child health services: a case-study of Wakiso District, Uganda
Published in Global health action (2024)“…Health systems are resilient if they absorb, adapt, and transform in response to shocks. Although absorptive and adaptive capacities have been demonstrated…”
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Evaluating kidney function using a point-of-care creatinine test in Ugandan children with severe malaria: a prospective cohort study
Published in BMC nephrology (06-11-2021)“…Acute kidney injury (AKI) disproportionately affects individuals in low-and middle-income countries (LMIC). However, LMIC-particularly countries in sub-Saharan…”
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Impact of early continuous positive airway pressure in the delivery room (DR-CPAP) on neonates < 1500 g in a low-resource setting: a protocol for a pilot feasibility and acceptability randomized controlled trial
Published in Pilot and feasibility studies (04-10-2024)“…Preterm birth is the leading cause of childhood mortality, and respiratory distress syndrome is the predominant cause of these deaths. Early continuous…”
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Neurocognitive function among HIV-infected children on protease inhibitor -based versus non-protease inhibitor based antiretroviral therapy in Uganda: a pilot study
Published in BMC pediatrics (26-04-2021)“…HIV infection is associated with significant neurocognitive deficits making maximization of cognitive function among children receiving antiretroviral therapy…”
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Alcohol use and associated factors among adolescent boys and young men in Kampala, Uganda
Published in Substance abuse treatment, prevention and policy (09-06-2021)“…Alcohol use leads to about 3 million deaths globally. The alcohol industry employs marketing strategies to establish their brands in the lives of young people…”
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Sequential disruptions to inflammatory and angiogenic pathways and risk of spontaneous preterm birth in Malawian women
Published in iScience (16-06-2023)“…Preterm birth is a leading cause of death in children under five years of age. We hypothesized that sequential disruptions to inflammatory and angiogenic…”
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Adherence to antiepileptic drugs among children attending a tertiary health unit in a low resource setting
Published in The Pan African medical journal (2014)“…Epilepsy is one of the neglected and highly stigmatised diseases, yet it is very common affecting about 70 million people worldwide. In Uganda, the estimated…”
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Severe Malaria and Academic Achievement
Published in Pediatrics (Evanston) (01-04-2023)“…Cerebral malaria (CM) and severe malarial anemia (SMA) are associated with neurocognitive impairment in childhood but their effects on long-term academic…”
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