Search Results - "Srivastava, Santosh"

Metabolic engineering of CHO cells for the development of a robust protein production platform by Gupta, Sanjeev Kumar, Srivastava, Santosh K, Sharma, Ankit, Nalage, Vaibhav H H, Salvi, Darshita, Kushwaha, Hiralal, Chitnis, Nikhil B, Shukla, Pratyoosh

“…Chinese hamster ovary (CHO) cells are the most preferred mammalian host used for the bio-pharmaceutical production. A major challenge in metabolic engineering…”
Get full text

Recent Advances in Medicinal Chemistry to Treat Tuberculosis - Part-I by Srivastava, Santosh K

Get more information

Recent Advances in Medicinal Chemistry to Treat Tuberculosis - Part-II by Srivastava, Santosh K

Get more information

Unveiling the impact of carbon-neutral policies on vital resources in Industry 4.0 driven smart manufacturing: A data-driven investigation by Bag, Surajit, Sabbir Rahman, Muhammad, Ghai, Sneha, Kumar Srivastava, Santosh, Kumar Singh, Rajesh, Mishra, Ruchi

Get full text

In silico and in vivo anti-malarial studies of 18β glycyrrhetinic acid from Glycyrrhiza glabra by Kalani, Komal, Agarwal, Jyoti, Alam, Sarfaraz, Khan, Feroz, Pal, Anirban, Srivastava, Santosh Kumar

“…Malaria is one of the most prevailing fatal diseases causing between 1.2 and 2.7 million deaths all over the world each year. Further, development of…”
Get full text

Comprehensive assessment of T-cell receptor β-chain diversity in αβ T cells by Robins, Harlan S., Campregher, Paulo V., Srivastava, Santosh K., Wacher, Abigail, Turtle, Cameron J., Kahsai, Orsalem, Riddell, Stanley R., Warren, Edus H., Carlson, Christopher S.

“…The adaptive immune system uses several strategies to generate a repertoire of T- and B-cell antigen receptors with sufficient diversity to recognize the…”
Get full text

Dihydroartemisinin and its Analogs: A New Class of Antitubercular Agents by Kalani, Komal, Chaturvedi, Vinita, Trivedi, Priyanka, Tondon, Sudeep, Srivastava, Santosh Kumar

“…Tuberculosis is one of the leading causes of mortality worldwide. Resistance against the frontline anti-tubercular drugs has worsened the already alarming…”
Get more information

Antibiotics potentiating potential of catharanthine against superbug Pseudomonas aeruginosa by Dwivedi, Gaurav Raj, Tyagi, Rekha, Sanchita, Tripathi, Shubhandra, Pati, Sanghamitra, Srivastava, Santosh K., Darokar, Mahendra P., Sharma, Ashok

“…Multidrug resistance (MDR) put an alarming situation like preantibiotic era which compels us to invigorate the basic science of anti-infective chemotherapy…”
Get full text

Design, synthesis and in vitro evaluation of 18β-glycyrrhetinic acid derivatives for anticancer activity against human breast cancer cell line MCF-7 by Yadav, Dharmendra Kumar, Kalani, Komal, Singh, Abhishek K, Khan, Feroz, Srivastava, Santosh K, Pant, Aditya B

“…In the present work, QSAR model was derived by multiple linear regression method for the prediction of anticancer activity of 18β-glycyrrhetinic acid…”
Get more information

Overlap and effective size of the human CD8+ T cell receptor repertoire by Robins, Harlan S, Srivastava, Santosh K, Campregher, Paulo V, Turtle, Cameron J, Andriesen, Jessica, Riddell, Stanley R, Carlson, Christopher S, Warren, Edus H

“…Diversity in T lymphocyte antigen receptors is generated by somatic rearrangement of T cell receptor (TCR) genes and is concentrated within the third…”
Get more information

Design, Synthesis, DFT, docking Studies, and antimicrobial evaluation of novel benzimidazole containing sulphonamide derivatives by Singh, Kajal, Singh, Vishal K., Mishra, Richa, Sharma, Ashwani, Pandey, Archana, Srivastava, Santosh K., Chaurasia, Himani

“…[Display omitted] •Imidazo-sulphonamide derivatives have been synthesized as antimicrobial agents.•Pharmacokinetic profile was analyzed through ADMET…”
Get full text

Nano Particles: Emerging Warheads Against Bacterial Superbugs by Dwivedi, Gaurav Raj, Sanchita, Singh, D P, Sharma, Ashok, Darokar, Mahendra P, Srivastava, Santosh K

“…Infectious diseases are one of the major causes of morbidity and mortality in children in developing and underdeveloped countries. Limited knowledge of targets…”
Get more information

Palindromic nucleotide analysis in human T cell receptor rearrangements by Srivastava, Santosh K, Robins, Harlan S

“…Diversity of T cell receptor (TCR) genes is primarily generated by nucleotide insertions upon rearrangement from their germ line-encoded V, D and J segments…”
Get full text

QSAR and docking studies on capsazepine derivatives for immunomodulatory and anti-inflammatory activity by Shukla, Aparna, Sharma, Pooja, Prakash, Om, Singh, Monika, Kalani, Komal, Khan, Feroz, Bawankule, Dnyaneshwar Umrao, Luqman, Suaib, Srivastava, Santosh Kumar

“…Capsazepine, an antagonist of capsaicin, is discovered by the structure and activity relationship. In previous studies it has been found that capsazepine has…”
Get full text

Synthesis and Structural Activity Relationship Study of Ursolic Acid Derivatives as Antitubercular Agent by Vishwakarma, Sadhna, Srivastava, Santosh K, Khare, Naveen K, Chaubey, Shiwa, Chaturvedi, Vinita, Trivedi, Priyanka, Khan, Sana, Khan, Feroz

“…The chemical transformation of ursolic acid (UA) into novel C-3 aryl ester derivatives and and assessment of their antitubercular potential. UA is a natural…”
Get more information

Ab initio and DFT studies of the structure and vibrational spectra of anhydrous caffeine by Srivastava, Santosh K., Singh, Vipin B.

“…[Display omitted] •Molecular geometry of anhydrous caffeine was optimized at MP2/6-311++G(d,p).•Calculated vibrational spectra at B3LYP/6-311++G(2d,2p) level…”
Get full text

Comparative Genomics and Metabolomics Analyses of Clavulanic Acid-Producing Streptomyces Species Provides Insight Into Specialized Metabolism by AbuSara, Nader F., Piercey, Brandon M., Moore, Marcus A., Shaikh, Arshad Ali, Nothias, Louis-Félix, Srivastava, Santosh K., Cruz-Morales, Pablo, Dorrestein, Pieter C., Barona-Gómez, Francisco, Tahlan, Kapil

“…Clavulanic acid is a bacterial specialized metabolite, which inhibits certain serine β-lactamases, enzymes that inactivate β-lactam antibiotics to confer…”
Get full text

In vivo functional analysis of a class A β-lactamase-related protein essential for clavulanic acid biosynthesis in Streptomyces clavuligerus by Srivastava, Santosh K, King, Kelcey S, AbuSara, Nader F, Malayny, Chelsea J, Piercey, Brandon M, Wilson, Jaime A, Tahlan, Kapil

“…In Streptomyces clavuligerus, the gene cluster involved in the biosynthesis of the clinically used β-lactamase inhibitor clavulanic acid contains a gene (orf12…”
Get full text

Large-scale separation of antipsychotic alkaloids from Rauwolfia tetraphylla L. by pH-zone-refining fast centrifugal partition chromatography by Maurya, Anupam, Gupta, Shikha, Srivastava, Santosh K.

“…pH‐zone‐refining centrifugal partition chromatography was successively applied in the large‐scale separation of close Rf antipsychotic indole alkaloids…”
Get full text

In Vitro, In Silico and Ex Vivo Studies of Dihydroartemisinin Derivatives as Antitubercular Agents by Kalani, Komal, Alam, Sarfaraz, Chaturvedi, Vinita, Singh, Shyam, Khan, Feroz, Srivastava, Santosh Kumar

“…As a part of our drug discovery program for anti-tubercular agents, dihydroartemisinin (DHA-1) was screened against Mtb H37Rv, which showed moderate…”
Get more information