Search Results - "Srivastava, Sandeep K"

KS18, a Mcl-1 inhibitor, improves the effectiveness of bortezomib and overcomes resistance in refractory multiple myeloma by triggering intrinsic apoptosis by Al-Odat, Omar S, Elbezanti, Weam Othman, Gowda, Krishne, Srivastava, Sandeep K, Amin, Shantu G, Jonnalagadda, Subash C, Budak-Alpdogan, Tulin, Pandey, Manoj K

“…Despite a record number of clinical studies investigating various anti-myeloma treatments, the 5-year survival rate for multiple myeloma (MM) patients in the…”
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Regulatory T cells suppress T cell activation at the pathologic site of human visceral leishmaniasis by Rai, Ambak K, Thakur, Chandreshwar P, Singh, Amar, Seth, Tulika, Srivastava, Sandeep K, Singh, Pushpendra, Mitra, Dipendra K

“…Suppression of T cell response is thought to be involved in the pathogenesis of visceral leishmaniasis (VL). Regulatory T cell (Treg) mediated…”
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Structural Basis for Dimerization and Activity of Human PAPD1, a Noncanonical Poly(A) Polymerase by Bai, Yun, Srivastava, Sandeep K., Chang, Jeong Ho, Manley, James L., Tong, Liang

“…Poly(A) polymerases (PAPs) are found in most living organisms and have important roles in RNA function and metabolism. Here, we report the crystal structure of…”
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Comparative engraftment and clonality of macaque HSPCs expanded on human umbilical vein endothelial cells versus non-expanded cells by Srivastava, Sandeep K., Truitt, Lauren L., Wu, Chuanfeng, Glaser, Adam, Nolan, Daniel J., Ginsberg, Michael, Espinoza, Diego A., Koelle, Samson, Yabe, Idalia M., Yu, Kyung-Rok, Hong, Sogun, Sellers, Stephanie, Krouse, Allen, Bonifacino, Aylin, Metzger, Mark, Dagur, Pradeep K., Donahue, Robert E., Dunbar, Cynthia E., Panch, Sandhya R.

“…Ex vivo hematopoietic stem and progenitor cell (HSPC) expansion platforms are under active development, designed to increase HSPC numbers and thus engraftment…”
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LncRNA TMPO-AS1 Promotes Triple-Negative Breast Cancer by Sponging miR-383-5p to Trigger the LDHA Axis by Vats, Prerna, Singh, Jai, Srivastava, Sandeep K, Kumar, Ashok, Nema, Rajeev

“…Understanding the heterogeneous nature of breast cancer, including the role of LDHA expression regulation via non-coding RNAs in prognosis, is still unknown,…”
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Effect of Cryopreservation on Autologous Chimeric Antigen Receptor T Cell Characteristics by Panch, Sandhya R., Srivastava, Sandeep K., Elavia, Nasha, McManus, Andrew, Liu, Shutong, Jin, Ping, Highfill, Steven L., Li, Xiaobai, Dagur, Pradeep, Kochenderfer, James N., Fry, Terry J., Mackall, Crystal L., Lee, Daniel, Shah, Nirali N., Stroncek, David F.

“…As clinical applications for chimeric antigen receptor T cell (CART) therapy extend beyond early phase trials, commercial manufacture incorporating…”
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Influence of the AgrC-AgrA complex on the response time of Staphylococcus aureus quorum sensing by Srivastava, Sandeep K, Rajasree, Kalagiri, Fasim, Aneesa, Arakere, Gayathri, Gopal, Balasubramanian

“…The Staphylococcus aureus agr quorum-sensing system plays a major role in the transition from the persistent to the virulent phenotype. S. aureus agr type I to…”
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Association between Severe Early Childhood Caries, Dietary Preferences, and 2nd Digit–4th Digit (2D:4D) Ratio by Yeluri, Ramakrishna, Garg, Nishita, Pathivada, Lumbini, Srivastava, Sandeep K

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Mcl-1 Inhibition: Managing Malignancy in Multiple Myeloma by Al-Odat, Omar S., von Suskil, Max, Chitren, Robert J., Elbezanti, Weam O., Srivastava, Sandeep K., Budak-Alpddogan, Tulin, Jonnalagadda, Subash C., Aggarwal, Bharat B., Pandey, Manoj

“…Multiple myeloma (MM) is a plasma cells neoplasm. The overexpression of Bcl-2 family proteins, particularly myeloid cell leukemia 1 (Mcl-1), plays a critical…”
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Intracellular delivery of peptide cargos using iron oxide based nanoparticles: studies on antitumor efficacy of a BCL-2 converting peptide, NuBCP-9 by Kumar, Manoj, Singh, Gurpal, Sharma, Sapna, Gupta, Dikshi, Bansal, Vivek, Arora, Vikas, Bhat, Madhusudan, Srivastava, Sandeep K, Sapra, Sameer, Kharbanda, Surender, Dinda, Amit K, Singh, Harpal

“…Delivering peptides into cells targeting the undruggable oncoproteins is an emerging area in cancer therapeutics. Here we report a novel nanoparticle-based…”
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Abbreviated T-Cell Activation on the Automated Clinimacs Prodigy Device Enhances Bispecific CD19/22 Chimeric Antigen Receptor T-Cell Viability and Fold Expansion, Reducing Total Culture Duration by Srivastava, Sandeep K, Panch, Sandhya R., Jin, Jianjian, Shalabi, Haneen, Shah, Nirali N., Highfill, Steven L, Stroncek, David F.

“…Introduction: As clinical applications for Chimeric Antigen Receptor (CAR) T-cell therapy expand, cell manufacturing incorporating closed-system, automated…”
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Abstract 3952: A novel Mcl-1 inhibitor induces cells death in a caspase-dependent manner and increases the efficacies of Venetoclax and ABT-737 in multiple myeloma cells by Al-Odat, Omar S., Tripathi, Rahul S., Srivastava, Sandeep K., Gowda, Krishne, Amin, Shantu G., Budak-Alpdogan, Tulin, Jonnalagadda, Subash C., Pandey, Manoj K.

“…Abstract Multiple myeloma (MM) is a deadly malignancy of the blood, characterized by the uncontrolled proliferation of plasma cells. MM is challenging to…”
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Managing of GIS projects m infrastructure development by Kaushal, Ashok, Srivastava, Sandeep K

“…Good project planning, at the initial stage, is a key to its successful implementation. Majority of the GIS-based projects are challenging as they need…”
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Crystal structure of human PAPD1, a noncanonical poly(A) polymerase by Bai, Yun, Srivastava, Sandeep K., Chang, Jeong Ho, Manley, James L., Tong, Liang

“…Poly(A) polymerases (PAPs) are found in most living organisms and have important roles in RNA function and metabolism. Here we report the crystal structure of…”
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Managing of GIS projects in infrastructure development by Kaushal, Ashok, Srivastava, Sandeep K.

“…Good project planning, at the initial stage, is a key to its successful implementation. Majority of the GIS-based projects are challenging as they need…”
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Competing Endogenous TMPO-AS1-let-7c-5p- LDHA RNA Network Predicts the Prognosis of Lung Adenocarcinoma Patients by Nema, Rajeev, Vats, Prerna, Singh, Jai, Srivastava, Sandeep K, Kumar, Ashok

“…Lactate dehydrogenase is dysregulated in several cancer types. However, the mechanism of its dysregulation in lung cancer is not fully understood. We utilized…”
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High-yield synthesis and liquid-exfoliation of two- dimensional belt-like hafnium disulphide by Kaur, Harneet, Yadav, Sandeep, Srivastava, Avanish K., Singh, Nidhi, Rath, Shyama, Schneider, Jörg J., Sinha, Om P., Srivastava, Ritu

“…Producing environmentally stable monolayers and few-layers of hafnium disulphide （HfS2） with a high yield to reveal its unlocked electronic and optoelectronic…”
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