Search Results - "Srivastava, Lalit K."

Loss of dysbindin-1 in excitatory neurons in mice impacts NMDAR-dependent behaviors, neuronal morphology and synaptic transmission in the ventral hippocampus by Bhardwaj, Sanjeev K., Nath, Moushumi, Wong, Tak Pan, Srivastava, Lalit K.

“…Dysbindin-1, a protein encoded by the schizophrenia susceptibility gene DTNBP1 , is reduced in the hippocampus of schizophrenia patients. It is expressed in…”
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Behavioral and cellular responses to circadian disruption and prenatal immune activation in mice by Delorme, Tara C., Ozell-Landry, William, Cermakian, Nicolas, Srivastava, Lalit K.

“…Most individuals with neurodevelopmental disorders (NDDs), including schizophrenia and autism spectrum disorders, experience disruptions in sleep and circadian…”
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Prenatal Immune Challenge in Mice Leads to Partly Sex-Dependent Behavioral, Microglial, and Molecular Abnormalities Associated with Schizophrenia by Hui, Chin W, St-Pierre, Abygaël, El Hajj, Hassan, Remy, Yvan, Hébert, Sébastien S, Luheshi, Giamal N, Srivastava, Lalit K, Tremblay, Marie-Ève

“…Epidemiological studies revealed that environmental factors comprising prenatal infection are strongly linked to risk for later development of neuropsychiatric…”
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Role of prefrontal cortical 5-HT2A receptors and serotonin transporter in the behavioral deficits in post-pubertal rats following neonatal lesion of the ventral hippocampus by Mitazaki, Satoru, Nakagawasai, Osamu, Onogi, Hiroshi, Watanabe, Kenya, Takahashi, Kohei, Tan-No, Koichi, Quirion, Rémi, Srivastava, Lalit K, Tadano, Takeshi

“…•NVHL rats show an enhancement of 5-HT2A receptor-associated behavior and PPI deficits at post-puberty.•NVHL-induced PPI deficits were reversed by atypical…”
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Effect of maternal lipopolysaccharide administration on the development of dopaminergic receptors and transporter in the rat offspring by Baharnoori, Moogeh, Bhardwaj, Sanjeev K, Srivastava, Lalit K

“…Epidemiological evidence supports that maternal infection during gestation are notable risk factors for developmental mental illnesses including schizophrenia…”
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The Atypical Antipsychotic Agent, Clozapine, Protects Against Corticosterone-Induced Death of PC12 Cells by Regulating the Akt/FoxO3a Signaling Pathway by Zeng, Zhiwen, Wang, Xue, Bhardwaj, Sanjeev K., Zhou, Xuanhe, Little, Peter J, Quirion, Remi, Srivastava, Lalit K., Zheng, Wenhua

“…Schizophrenia is one of the most severe psychiatric disorders. Increasing evidence implicates that neurodegeneration is a component of schizophrenia pathology…”
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Role of Prefrontal Cortex Anti- and Pro-inflammatory Cytokines in the Development of Abnormal Behaviors Induced by Disconnection of the Ventral Hippocampus in Neonate Rats by Joseph, Antoneta T, Bhardwaj, Sanjeev K, Srivastava, Lalit K

“…Neonatal disconnection of ventral hippocampus (VH) outputs in rats has been reported to lead to post-pubertal behavioral and synaptic changes of relevance to…”
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Alterations in prefrontal cortical neuregulin-1 levels in post-pubertal rats with neonatal ventral hippocampal lesions by Watanabe, Kenya, Nakagawasai, Osamu, Kanno, Syu-Ichi, Mitazaki, Satoru, Onogi, Hiroshi, Takahashi, Kohei, Watanabe, Kei-Ichiro, Tan-No, Koichi, Ishikawa, Masaaki, Srivastava, Lalit K, Quirion, Remi, Tadano, Takeshi

“…Genetic studies in humans have implicated the gene encoding neuregulin-1 (NRG-1) as a candidate susceptibility gene for schizophrenia. Furthermore, it has been…”
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Schizophrenia-like features in transgenic mice overexpressing human HO-1 in the astrocytic compartment by Song, Wei, Zukor, Hillel, Lin, Shih-Hsiung, Hascalovici, Jacob, Liberman, Adrienne, Tavitian, Ayda, Mui, Jeannie, Vali, Hojatollah, Tong, Xin-Kang, Bhardwaj, Sanjeev K, Srivastava, Lalit K, Hamel, Edith, Schipper, Hyman M

“…Delineation of key molecules that act epigenetically to transduce diverse stressors into established patterns of disease would facilitate the advent of…”
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A sexually dichotomous, autistic‐like phenotype is induced by Group B Streptococcus maternofetal immune activation by Allard, Marie‐Julie, Bergeron, Julie D., Baharnoori, Moogeh, Srivastava, Lalit K., Fortier, Louis‐Charles, Poyart, Claire, Sébire, Guillaume

“…Group B Streptococcus (GBS) is a commensal bacterium present in the lower genital tract of 15–30% of healthy pregnant women. GBS is the leading cause of…”
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Can the neurodevelopmental theory account for sex differences in schizophrenia across the life span? by Baldwin, Carolyn Helene, BSc, MD (candidate), Srivastava, Lalit K., MSc, PhD

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Behavioral characterization of dysbindin-1 deficient sandy mice by Bhardwaj, Sanjeev K., Baharnoori, Moogeh, Sharif-Askari, Bahram, Kamath, Aarthi, Williams, Sylvain, Srivastava, Lalit K.

“…Dysbindin-1 (dystrobrevin binding protein-1) has been reported as a candidate gene associated with schizophrenia. Dysbindin-1 mRNA and protein levels are…”
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Loss of dysbindin-1, a risk gene for schizophrenia, leads to impaired group 1 metabotropic glutamate receptor function in mice by Bhardwaj, Sanjeev K, Ryan, Richard T, Wong, Tak Pan, Srivastava, Lalit K

“…The expression of dysbindin-1, a protein coded by the risk gene dtnbp1, is reduced in the brains of schizophrenia patients. Evidence indicates a role of…”
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Conservation Agricultural Practices Impact on Soil Organic Carbon, Soil Aggregation and Greenhouse Gas Emission in a Vertisol by Jayaraman, Somasundaram, Sahu, Meenakshi, Sinha, Nishant K., Mohanty, Monoranjan, Chaudhary, Ranjeet S., Yadav, Brijesh, Srivastava, Lalit K., Hati, Kuntal M., Patra, Ashok K., Dalal, Ram C.

“…Conservation agriculture (CA), comprising of minimum soil disturbance and crop residue retention (>30%), with a diversified cropping system, has become…”
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The circadian system: A neglected player in neurodevelopmental disorders by Bouteldja, Ahmed A., Penichet, Danae, Srivastava, Lalit K., Cermakian, Nicolas

“…Patients with neurodevelopmental disorders, such as autism spectrum disorder, often display abnormal circadian rhythms. The role of the circadian system in…”
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Are Circadian Disturbances a Core Pathophysiological Component of Schizophrenia? by Delorme, Tara C., Srivastava, Lalit K., Cermakian, Nicolas

“…Schizophrenia is a multifactorial disorder caused by a combination of genetic variations and exposure to environmental insults. Sleep and circadian rhythm…”
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Altered circadian rhythms in a mouse model of neurodevelopmental disorders based on prenatal maternal immune activation by Delorme, Tara C., Srivastava, Lalit K., Cermakian, Nicolas

“…•Locomotor activity was studied in offspring after maternal immune activation (MIA).•Male offspring of MIA dams exhibited increased (subjective) day locomotor…”
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Altered excitatory and decreased inhibitory transmission in the prefrontal cortex of male mice with early developmental disruption to the ventral hippocampus by Nath, Moushumi, Bhardwaj, Sanjeev K, Srivastava, Lalit K, Wong, Tak Pan

“…Ventral hippocampal (vHPC)-prefrontal cortical (PFC) pathway dysfunction is a core neuroimaging feature of schizophrenia. However, mechanisms underlying…”
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Neurodevelopmental insights into circuit dysconnectivity in schizophrenia by Nath, Moushumi, Wong, Tak Pan, Srivastava, Lalit K.

“…Schizophrenia is increasingly being recognized as a disorder of brain circuits of developmental origin. Animal models, however, have been technically limited…”
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cDNA microarray and proteomic approaches in the study of brain diseases: focus on schizophrenia and Alzheimer's disease by Marcotte, Eric R, Srivastava, Lalit K, Quirion, Rémi

“…Recent advances in experimental genomics and proteomics, coupled with the wealth of sequence information available for a variety of organisms, have tremendous…”
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