Search Results - "Srinouanprachanh, Sengkeo L."
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Acetaminophen-induced Liver Injury Is Attenuated in Male Glutamate-cysteine Ligase Transgenic Mice
Published in The Journal of biological chemistry (29-09-2006)“…Acetaminophen overdose is a leading cause of drug-related acute liver failure in the United States. Glutathione, a tripeptide antioxidant protects cells…”
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Association Between CYP2C9 Genetic Variants and Anticoagulation-Related Outcomes During Warfarin Therapy
Published in JAMA : the journal of the American Medical Association (03-04-2002)“…CONTEXT Warfarin is a commonly used anticoagulant that requires careful clinical management to balance the risks of overanticoagulation and bleeding with those…”
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The Prevalence of CYP2C8, 2C9, 2J2, and Soluble Epoxide Hydrolase Polymorphisms in African Americans With Hypertension
Published in American journal of hypertension (01-10-2005)“…The cytochrome P450 (CYP) epoxygenase pathway produces arachidonic acid metabolites that are vasoactive, that affect renal sodium handling, and that have been…”
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A case study of acenocoumarol sensitivity and genotype‐phenotype discordancy explained by combinations of polymorphisms in VKORC1 and CYP2C9
Published in British journal of clinical pharmacology (01-11-2006)“…Aims To determine the cause of a genotype‐phenotype discordancy for acenocoumarol sensitivity. Methods A patient, highly sensitive to acenocoumarol, and…”
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Genetic Susceptibility to Prostate Cancer: Prostate-Specific Antigen and Its Interaction with the Androgen Receptor (United States)
Published in Cancer causes & control (01-03-2006)“…Objective To determine whether directly observed prostate-specific antigen (PSA) promoter diploid haplotype, either alone or in conjunction with androgen…”
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