Search Results - "Srinivasan, Swetha"

Barriers and facilitators for cascade testing in genetic conditions: a systematic review by Srinivasan, Swetha, Won, Nae Yeon, Dotson, W David, Wright, Sarah T, Roberts, Megan C

“…Cascade testing is the process of offering genetic counseling and testing to at-risk relatives of an individual who has been diagnosed with a genetic…”
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Lymphatic transport of exosomes as a rapid route of information dissemination to the lymph node by Srinivasan, Swetha, Vannberg, Fredrik O., Dixon, J. Brandon

“…It is well documented that cells secrete exosomes, which can transfer biomolecules that impact recipient cells’ functionality in a variety of physiologic and…”
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Comparison of Yttrium-90 Radioembolization and Transcatheter Arterial Chemoembolization for the Treatment of Unresectable Hepatocellular Carcinoma by Kooby, David A., MD, Egnatashvili, Vasili, MD, Srinivasan, Swetha, MD, Chamsuddin, Abbas, MD, Delman, Keith A., MD, Kauh, John, MD, Staley, Charles A., MD, Kim, Hyun S., MD

“…Purpose To compare the effectiveness and toxicity of transcatheter arterial chemoembolization (chemoembolization) and yttrium-90–labeled microspheres…”
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Development and initial testing of a multi-stakeholder intervention for Lynch syndrome cascade screening: an intervention mapping approach by Passero, Lauren, Srinivasan, Swetha, Grewe, Mary E, Leeman, Jennifer, Berg, Jonathan, Reuland, Daniel, Roberts, Megan C

“…Lynch syndrome is an underdiagnosed hereditary condition carrying an increased lifetime risk for colorectal and endometrial cancer and affecting nearly 1…”
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Barriers and Facilitators for Population Genetic Screening in Healthy Populations: A Systematic Review by Shen, Emily C, Srinivasan, Swetha, Passero, Lauren E, Allen, Caitlin G, Dixon, Madison, Foss, Kimberly, Halliburton, Brianna, Milko, Laura V, Smit, Amelia K, Carlson, Rebecca, Roberts, Megan C

“…Studies suggest that 1-3% of the general population in the United States unknowingly carry a genetic risk factor for a common hereditary disease. Population…”
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Assessment of methods for serum extracellular vesicle small RNA sequencing to support biomarker development by Srinivasan, Swetha, Duval, Manuel X., Kaimal, Vivek, Cuff, Carolyn, Clarke, Stephen H.

“…Extracellular vesicles (EVs) have great potential as a source for clinically relevant biomarkers since they can be readily isolated from biofluids and carry…”
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WattTime: Novel System Power Model and Completion Time Model for DVFS-Enabled Servers by Srinivasan, Swetha P. T., Bellur, Umesh

“…Power consumption costs takes up to half of the operational expenses of data centers, making power management a critical concern. Advances in processor…”
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Incidental chylous fluid during hernia repair may be a harbinger of malrotation by Zarroug, Abdalla E, Srinivasan, Swetha K, Wulkan, Mark L

“…Abstract A previously asymptomatic 12-week-old male infant was found to have chylous ascites within his peritoneal hernia sacs during elective open bilateral…”
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Prognostic value of patient-reported outcomes in advanced or metastatic melanoma patients treated with immunotherapy: Findings from the CheckMate-067 study by Schadendorf, Dirk, Lord-Bessen, Jennifer, Ejzykowicz, Flavia, Shi, Ling, Yu, Peiwen, Srinivasan, Swetha

“…Patient-reported outcomes (PROs) that predict survival in cancer patients have yet to be realized as practical tools for clinicians to make better treatment…”
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An indirect assessment of individual-level association between disease-free survival (DFS) and overall survival (OS) for resectable esophageal or gastroesophageal junction cancer (EC/GEJC): A pooled analysis of randomized controlled trials (RCTs) by an illness-death model by Alagoz, Oguzhan, Ajani, Jaffer A., Srinivasan, Swetha, Kim, Inkyu, Singh, Prianka, Kurt, Murat

“…369 Background: Validation of intermediate endpoints such as DFS as surrogates for overall survival (OS) in RCTs at individual-level remains as a challenge due…”
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Examining the role of language competency in genetic testing awareness among adults in the United States by Passero, Lauren, Srinivasan, Swetha, Roberts, Megan C.

“…English language competency, as a component of health literacy, is associated with increased awareness and uptake of health‐related genetic testing. The…”
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Evaluating Use of Biomarker Testing among Patients with Advanced Non-small Cell Lung Cancer by Srinivasan, Swetha

“…Among patients diagnosed with advanced non-small cell lung cancer (aNSCLC), biomarker testing is used to profile genetic mutations and protein levels in the…”
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52990 MRPGRX2 Antagonist EP262 Inhibits Mast Cell Activation and Attenuates Disease in a Mouse Model of Atopic Dermatitis by Wollam, Joshua, Solomon, Michelle, Villescaz, Christiane, Srinivasan, Swetha, Charlot, Brittney, Vest, Alan, Napora, Jim, Cavarlez, Christine, Dvorak, Lisa, Nevarez, Andres, Viswanath, Veena

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Uptake of Genetic Testing Among Cancer Patients at Risk for Lynch Syndrome in the National Health Interview Survey by Actkins, Ky’Era V., Srinivasan, Swetha, Spees, Lisa P., Turbitt, Erin, Allen, Caitlin G., Roberts, Megan C.

“…Lynch syndrome (LS) is the most common inherited cancer syndrome that increases the risk of developing colorectal (CRC) and endometrial cancer (EC). Universal…”
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Stakeholder Perspectives on Overcoming Barriers to Cascade Testing in Lynch Syndrome: A Qualitative Study by Srinivasan, Swetha, Hampel, Heather, Leeman, Jennifer, Patel, Amit, Kulchak Rahm, Alanna, Reuland, Daniel S, Roberts, Megan C

“…Cascade testing (i.e., genetic testing of family members of individuals with disease) among families affected by hereditary cancer disorders, such as Lynch…”
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Clinical outcomes of adjuvant nivolumab in resected stage III melanoma: comparison of CheckMate 238 trial and real-world data by Moser, Justin C., Bhatia, Shailender, Amin, Asim, Pavlick, Anna C., Betts, Keith A., Du, Ella Xiaoyan, Poretta, Tayla, Shelley, Karishma, Srinivasan, Swetha, Sakkal, Leon Alan, Palaia, Jennell, Lobo, Maurice, Pe Benito, Melanie, Linton, Joshua A., Chen, Yan, Xu, Churong, Yin, Lei, Sundar, Manasvi, Weber, Jeffrey

“…Objectives Nivolumab is approved as adjuvant therapy for resected stage III/IV melanoma based on the phase 3 CheckMate 238 trial. This analysis compared…”
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Uptake of Genetic Testing Among Patients with Cancer At Risk for Lynch Syndrome in the National Health Interview Survey by Actkins, Ky'Era V, Srinivasan, Swetha, Spees, Lisa P, Turbitt, Erin, Allen, Caitlin G, Roberts, Megan C

“…Lynch syndrome is the most common inherited cancer syndrome that increases the risk of developing colorectal and endometrial cancer. Universal screening…”
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miRNA-26b Overexpression in Ulcerative Colitis-associated Carcinogenesis by Benderska, Natalya, Dittrich, Anna-Lena, Knaup, Sabine, Rau, Tilman T, Neufert, Clemens, Wach, Sven, Fahlbusch, Fabian B, Rauh, Manfred, Wirtz, Ralph M, Agaimy, Abbas, Srinivasan, Swetha, Mahadevan, Vijayalakshmi, Rümmele, Petra, Rapti, Emmanouela, Gazouli, Maria, Hartmann, Arndt, Schneider-Stock, Regine

“…Longstanding ulcerative colitis (UC) bears a high risk for development of UC-associated colorectal carcinoma (UCC). The inflammatory microenvironment…”
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TLR-exosomes exhibit distinct kinetics and effector function by Srinivasan, Swetha, Su, Michelle, Ravishankar, Shashidhar, Moore, James, Head, PamelaSara, Dixon, J. Brandon, Vannberg, Fredrik

“…The innate immune system is vital to rapidly responding to pathogens and Toll-like receptors (TLRs) are a critical component of this response. Nanovesicular…”
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Factors Associated With Receipt of Molecular Testing and its Impact on Time to Initial Systemic Therapy in Metastatic Non-Small Cell Lung Cancer by Osazuwa-Peters, Oyomoare L., Wilson, Lauren E., Check, Devon K., Roberts, Megan C., Srinivasan, Swetha, Clark, Amy G., Crawford, Jeffrey, Chrischilles, Elizabeth, Carnahan, Ryan M., Campbell, W. Scott, Cowell, Lindsay G., Greenlee, Robert, Abbott, Andrea M., Mosa, Abu S.M., Mandhadi, Vasanthi, Stoddard, Alexander, Dinan, Michaela A.

“…Despite recommendations for molecular testing irrespective of patient characteristics, differences exist in receipt of molecular testing for oncogenic drivers…”
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