Search Results - "Srinivasan, Pugazhendhi"
-
1
Suppressing STAT5 signaling affects osteosarcoma growth and stemness
Published in Cell death & disease (24-02-2020)“…Osteosarcoma (OS) is the most common primary bone tumor that primarily affects children and adolescents. Studies suggested that dysregulation JAK/STAT…”
Get full text
Journal Article -
2
Alterations of mucosal microbiota in the colon of patients with inflammatory bowel disease revealed by real time polymerase chain reaction amplification of 16S ribosomal ribonucleic acid
Published in Indian journal of medical research (New Delhi, India : 1994) (01-07-2015)“…Alterations in microbial communities closely associated with the intestinal mucosa are likely to be important in the pathogenesis of inflammatory bowel disease…”
Get full text
Journal Article -
3
NEC-like intestinal injury is ameliorated by Lactobacillus rhamnosus GG in parallel with SIGIRR and A20 induction in neonatal mice
Published in Pediatric research (01-10-2020)“…Background Exaggerated Toll-like receptor (TLR) signaling and intestinal dysbiosis are key contributors to necrotizing enterocolitis (NEC). Lactobacillus…”
Get full text
Journal Article -
4
Clostridium leptum group bacteria abundance and diversity in the fecal microbiota of patients with inflammatory bowel disease: a case-control study in India
Published in BMC gastroenterology (26-01-2013)“…Alterations in the fecal bacterial flora occur in inflammatory bowel disease (IBD). We examined the abundance and diversity of Clostridium leptum group, an…”
Get full text
Journal Article -
5
Protective association of tumor necrosis factor superfamily 15 (TNFSF15) polymorphic haplotype with Ulcerative Colitis and Crohn's disease in an Indian population
Published in PloS one (12-12-2014)“…Tumor necrosis factor superfamily (TNFSF) proteins are involved in the genesis of inflammatory bowel disease (IBD). We examined the association of seven single…”
Get full text
Journal Article -
6
Association of IRGM gene mutations with inflammatory bowel disease in the Indian population
Published in PloS one (05-09-2014)“…Mutations in the IRGM gene have been associated with Crohn's disease in several populations but have not been explored in Indian patients with this disease…”
Get full text
Journal Article -
7
Association of ATG16L1 gene haplotype with inflammatory bowel disease in Indians
Published in PloS one (19-05-2017)“…Inflammatory bowel disease (IBD) is characterized by multigenic inheritance. Defects in autophagy related genes are considered to show genetic heterogeneity…”
Get full text
Journal Article -
8
A phase 2 randomized controlled trial of oral resistant starch supplements in the prevention of acute radiation proctitis in patients treated for cervical cancer
Published in Journal of cancer research and therapeutics (01-10-2019)“…Background: Radiation induced proctitis is frequently encountered during the radiation therapy of cervical and prostate cancers that causes pain and…”
Get full text
Journal Article -
9
Faecal microbiota of healthy adults in south India: Comparison of a tribal & a rural population
Published in Indian journal of medical research (New Delhi, India : 1994) (01-02-2017)“…The relevance of the gut microbiota to human health is increasingly appreciated. The objective of this study was to compare the gut microbiota of a group of…”
Get full text
Journal Article -
10
Human Leukocyte Antigen DQ (HLA‐DQ) genotypes and haplotypes and their association with phenotype in patients with celiac disease in India
Published in JGH open (01-10-2021)“…Background and Aim Human Leukocyte Antigen DQ (HLA‐DQ) genotypes play a permissive role in the genesis of celiac disease (CeD). In this case–control study, we…”
Get full text
Journal Article -
11
Probiotic administration alters the gut flora and attenuates colitis in mice administered dextran sodium sulfate
Published in Journal of gastroenterology and hepatology (01-12-2008)“…Background: Probiotics are used in the therapy of inflammatory bowel disease. This study aimed to determine whether prior administration of probiotic…”
Get full text
Journal Article -
12
Effect of Various Preterm Infant Milk Formulas on NEC-Like Gut Injury in Mice
Published in Frontiers in pediatrics (06-07-2022)“…Formula feeding is an important risk factor for the development of necrotizing enterocolitis in preterm infants. The potential harmful effects of different…”
Get full text
Journal Article -
13
Effect of Native and Acetylated Dietary Resistant Starches on Intestinal Fermentative Capacity of Normal and Stunted Children in Southern India
Published in International journal of environmental research and public health (15-10-2019)“…The health benefits of dietary amylase resistant starch (RS) arise from intestinal microbial fermentation and generation of short chain fatty acids (SCFA). We…”
Get full text
Journal Article -
14
Effect of yoghurt containing Bifidobacterium lactis Bb12® on faecal excretion of secretory immunoglobulin A and human beta-defensin 2 in healthy adult volunteers
Published in Nutrition journal (23-12-2011)“…Probiotics are used to provide health benefits. The present study tested the effect of a probiotic yoghurt on faecal output of beta-defensin and immunoglobulin…”
Get full text
Journal Article -
15
Impact of Weight Management on Obesity-Driven Biomarkers of Prostate Cancer Progression
Published in The Journal of urology (01-04-2024)“…Excess body and visceral fat increase the risk of death from prostate cancer (PCa). This phase II study aimed to test whether weight reduction by > 5% total…”
Get full text
Journal Article -
16
Prevalence of Adult Celiac Disease in India: Regional Variations and Associations
Published in The American journal of gastroenterology (01-01-2016)“…Although celiac disease (CeD) affects 1% of people in the northern part of India, it is believed to be uncommon in the southern and northeastern parts because…”
Get full text
Journal Article -
17
Protective Association of Tumor Necrosis Factor Superfamily 15
Published in PloS one (12-12-2014)“…Background Tumor necrosis factor superfamily (TNFSF) proteins are involved in the genesis of inflammatory bowel disease (IBD). We examined the association of…”
Get full text
Journal Article -
18
Evaluation of sarcopenia in patients receiving intravesical Bacillus Calmette-Guérin for non-muscle invasive bladder cancer
Published in Urologic oncology (01-10-2023)“…•Body composition analysis is feasible in bladder cancer patients with CT imaging.•Many (61%) of patients with NMIBC on BCG have sarcopenia.•More than…”
Get full text
Journal Article -
19
Prevalence and factors associated with gastroesophageal reflux disease in southern India: A community-based study
Published in Indian journal of gastroenterology (01-02-2019)“…Background and Aim Gastroesophageal reflux disease (GERD) is common worldwide with significant expenditure for health care. Community-based data on the…”
Get full text
Journal Article -
20
Abstract 654: Dietary interventions ameliorate infectious colitis through differential regulation of Lgr5
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Background: During inflammatory bowel disease (IBD), the disruption of the epithelial barrier and translocation of bacteria drive inappropriate immune…”
Get full text
Journal Article