Search Results - "Srinivasan, Karunya"
-
1
Quantitative description of glycan-receptor binding of influenza A virus H7 hemagglutinin
Published in PloS one (20-02-2013)“…In the context of recently emerged novel influenza strains through reassortment, avian influenza subtypes such as H5N1, H7N7, H7N2, H7N3 and H9N2 pose a…”
Get full text
Journal Article -
2
Quantitative characterization of glycan-receptor binding of H9N2 influenza A virus hemagglutinin
Published in PloS one (23-04-2013)“…Avian influenza subtypes such as H5, H7 and H9 are yet to adapt to the human host so as to establish airborne transmission between humans. However,…”
Get full text
Journal Article -
3
Correction: Quantitative Description of Glycan-Receptor Binding of Influenza A Virus H7 Hemagglutinin
Published in PloS one (30-12-2013)“…Please see the correct Figure 3B here: thumbnail Download: * PPT PowerPoint slide * PNG larger image * TIFF original image Figures Citation: Srinivasan K,…”
Get full text
Journal Article -
4
Trial START-001: A phase 1/2 study of STAR0602, a first-in-class, selective T cell receptor (TCR)-targeting, bifunctional antibody-fusion molecule, as monotherapy in patients with antigen-rich tumors post checkpoint inhibitor (CPI) treatment
Published in Journal of clinical oncology (01-06-2023)“…TPS2671 Background: Many patients do not respond to CPI-based therapies and most responders eventually develop resistance. Thus, the development of more…”
Get full text
Journal Article -
5
A T cell receptor β chain-directed antibody fusion molecule activates and expands subsets of T cells to promote antitumor activity
Published in Science translational medicine (29-11-2023)“…Despite the success of programmed cell death-1 (PD-1) and PD-1 ligand (PD-L1) inhibitors in treating solid tumors, only a proportion of patients respond. Here,…”
Get more information
Journal Article -
6
Characterization of Endogenous Human FcγRIII by Mass Spectrometry Reveals Site, Allele and Sequence Specific Glycosylation[S]
Published in Molecular & cellular proteomics (01-03-2019)“…Characterization of endogenous FcγRIII glycosylation from healthy donors with different FcγRIIIb genotypes reveals site specific, and allele specific…”
Get full text
Journal Article -
7
Abstract 561: Discovery of a potential best-in-class anti-CD38 therapeutic utilizing Fc multimerization
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…CD38 targeting antibodies are at different phases of clinical development, with daratumumab already approved as monotherapy and in combination with standards…”
Get full text
Journal Article -
8
Characterization of Endogenous Human FcγRIII by Mass Spectrometry Reveals Site, Allele and Sequence Specific Glycosylation
Published in Molecular & cellular proteomics (01-03-2019)“…The importance of IgG glycosylation, Fc-gamma receptor (FcγR) single nucleotide polymorphisms and FcγR copy number variations in fine tuning the immune…”
Get full text
Journal Article -
9
A Quantitative Microtiter Assay for Sialylated Glycoform Analyses Using Lectin Complexes
Published in Journal of biomolecular screening (01-07-2015)“…Fidelity of glycan structures is a key requirement for biotherapeutics, with carbohydrates playing an important role for therapeutic efficacy. Comprehensive…”
Get more information
Journal Article -
10
Quantitative Characterization of Glycan-Receptor Binding of H9N2 Influenza A Virus Hemagglutinin. e59550
Published in PloS one (01-04-2013)“…Avian influenza subtypes such as H5, H7 and H9 are yet to adapt to the human host so as to establish airborne transmission between humans. However,…”
Get full text
Journal Article