Search Results - "Srinivasan, Jagan"

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  1. 1

    Diverse states and stimuli tune olfactory receptor expression levels to modulate food-seeking behavior by McLachlan, Ian G, Kramer, Talya S, Dua, Malvika, DiLoreto, Elizabeth M, Gomes, Matthew A, Dag, Ugur, Srinivasan, Jagan, Flavell, Steven W

    Published in eLife (31-08-2022)
    “…Animals must weigh competing needs and states to generate adaptive behavioral responses to the environment. Sensorimotor circuits are thus tasked with…”
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    Tracking N- and C-termini of C. elegans polycystin-1 reveals their distinct targeting requirements and functions in cilia and extracellular vesicles by Walsh, Jonathon D, Wang, Juan, DeHart, Molly, Nikonorova, Inna A, Srinivasan, Jagan, Barr, Maureen M

    Published in PLoS genetics (27-12-2022)
    “…The cilium acts as an antenna receiving and sending signals, the latter via extracellular vesicles (EVs). In C. elegans and mammals, the Autosomal Dominant…”
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    A modular library of small molecule signals regulates social behaviors in Caenorhabditis elegans by Srinivasan, Jagan, von Reuss, Stephan H, Bose, Neelanjan, Zaslaver, Alon, Mahanti, Parag, Ho, Margaret C, O'Doherty, Oran G, Edison, Arthur S, Sternberg, Paul W, Schroeder, Frank C

    Published in PLoS biology (01-01-2012)
    “…The nematode C. elegans is an important model for the study of social behaviors. Recent investigations have shown that a family of small molecule signals, the…”
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    Predator-secreted sulfolipids induce defensive responses in C. elegans by Liu, Zheng, Kariya, Maro J., Chute, Christopher D., Pribadi, Amy K., Leinwand, Sarah G., Tong, Ada, Curran, Kevin P., Bose, Neelanjan, Schroeder, Frank C., Srinivasan, Jagan, Chalasani, Sreekanth H.

    Published in Nature communications (19-03-2018)
    “…Animals respond to predators by altering their behavior and physiological states, but the underlying signaling mechanisms are poorly understood. Using the…”
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    shortcut to identifying small molecule signals that regulate behavior and development in Caenorhabditis elegans by Pungaliya, Chirag, Srinivasan, Jagan, Fox, Bennett W, Malik, Rabia U, Ludewig, Andreas H, Sternberg, Paul W, Schroeder, Frank C

    “…Small molecule metabolites play important roles in Caenorhabditis elegans biology, but effective approaches for identifying their chemical structures are…”
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  7. 7

    Co-option of neurotransmitter signaling for inter-organismal communication in C. elegans by Chute, Christopher D., DiLoreto, Elizabeth M., Zhang, Ying K., Reilly, Douglas K., Rayes, Diego, Coyle, Veronica L., Choi, Hee June, Alkema, Mark J., Schroeder, Frank C., Srinivasan, Jagan

    Published in Nature communications (18-07-2019)
    “…Biogenic amine neurotransmitters play a central role in metazoan biology, and both their chemical structures and cognate receptors are evolutionarily…”
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  8. 8

    Microfluidic chamber arrays for whole-organism behavior-based chemical screening by Chung, Kwanghun, Zhan, Mei, Srinivasan, Jagan, Sternberg, Paul W, Gong, Emily, Schroeder, Frank C, Lu, Hang

    Published in Lab on a chip (01-01-2011)
    “…The nematode Caenorhabditis elegans is an important model organism in genetic research and drug screening because of its relative simplicity, ease of…”
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    Contrasting responses within a single neuron class enable sex-specific attraction in Caenorhabditis elegans by Narayan, Anusha, Venkatachalam, Vivek, Durak, Omer, Reilly, Douglas K., Bose, Neelanjan, Schroeder, Frank C., Samuel, Aravinthan D. T., Srinivasan, Jagan, Sternberg, Paul W.

    “…Animals find mates and food, and avoid predators, by navigating to regions within a favorable range of available sensory cues. How are these ranges set and…”
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    Improved Synthesis for Modular Ascarosides Uncovers Biological Activity by Zhang, Ying K, Sanchez-Ayala, Marco A, Sternberg, Paul W, Srinivasan, Jagan, Schroeder, Frank C

    Published in Organic letters (02-06-2017)
    “…A versatile synthesis of modular ascarosides, a family of signaling molecules from Caenorhabditis elegans and other nematodes, via hydrogenolysis of a cyclic…”
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    Targeted Metabolomics Reveals a Male Pheromone and Sex-Specific Ascaroside Biosynthesis in Caenorhabditis elegans by Izrayelit, Yevgeniy, Srinivasan, Jagan, Campbell, Sydney L, Jo, Yeara, von Reuss, Stephan H, Genoff, Margaux C, Sternberg, Paul W, Schroeder, Frank C

    Published in ACS chemical biology (17-08-2012)
    “…In the model organism Caenorhabditis elegans, a class of small molecule signals called ascarosides regulate development, mating, and social behaviors…”
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  12. 12

    Circuit mechanisms encoding odors and driving aging-associated behavioral declines in Caenorhabditis elegans by Leinwand, Sarah G, Yang, Claire J, Bazopoulou, Daphne, Chronis, Nikos, Srinivasan, Jagan, Chalasani, Sreekanth H

    Published in eLife (22-09-2015)
    “…Chemosensory neurons extract information about chemical cues from the environment. How is the activity in these sensory neurons transformed into behavior?…”
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    The draft genome and transcriptome of Panagrellus redivivus are shaped by the harsh demands of a free-living lifestyle by Srinivasan, Jagan, Dillman, Adler R, Macchietto, Marissa G, Heikkinen, Liisa, Lakso, Merja, Fracchia, Kelley M, Antoshechkin, Igor, Mortazavi, Ali, Wong, Garry, Sternberg, Paul W

    Published in Genetics (Austin) (01-04-2013)
    “…Nematodes compose an abundant and diverse invertebrate phylum with members inhabiting nearly every ecological niche. Panagrellus redivivus (the "microworm") is…”
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  14. 14

    Distinct neuropeptide-receptor modules regulate a sex-specific behavioral response to a pheromone by Reilly, Douglas K., McGlame, Emily J., Vandewyer, Elke, Robidoux, Annalise N., Muirhead, Caroline S., Northcott, Haylea T., Joyce, William, Alkema, Mark J., Gegear, Robert J., Beets, Isabel, Srinivasan, Jagan

    Published in Communications biology (31-08-2021)
    “…Dioecious species are a hallmark of the animal kingdom, with opposing sexes responding differently to identical sensory cues. Here, we study the response of C…”
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    Trypanocide Use and Molecular Characterization of Trypanosomes Resistant to Diminazene Aceturate in Cattle in Northern Côte D'Ivoire by Ekra, Jean-Yves, Mafie, Eliakunda Michael, Sonan, Henri, Kanh, Michael, Gragnon, Biégo Guillaume, N'Goran, Edouard K, Srinivasan, Jagan

    Published in Tropical medicine and infectious disease (01-09-2024)
    “…The resistance of trypanosomes to the doses of trypanocide administered by farmers to their animals acts as a real brake on efforts to control to combat…”
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    Ascaroside Expression in Caenorhabditis elegans Is Strongly Dependent on Diet and Developmental Stage by Kaplan, Fatma, Srinivasan, Jagan, Mahanti, Parag, Ajredini, Ramadan, Durak, Omer, Nimalendran, Rathika, Sternberg, Paul W, Teal, Peter E.A, Schroeder, Frank C, Edison, Arthur S, Alborn, Hans T

    Published in PloS one (15-03-2011)
    “…Background: The ascarosides form a family of small molecules that have been isolated from cultures of the nematode Caenorhabditis elegans. They are often…”
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    Genetic Diversity of Trypanosomes Infesting Cattle from Savannah District in North of Côte d'Ivoire Using Conserved Genomic Signatures: rRNA, ITS1 and gGAPDH by Ekra, Jean-Yves, Mafie, Eliakunda Michael, N'Goran, Edouard K, Kaba, Dramane, Gragnon, Biégo Guillaume, Srinivasan, Jagan

    Published in Pathogens (Basel) (01-03-2024)
    “…The potential danger to livestock from African animal trypanosomiasis is well known. However, the trypanosome species circulating in cattle and their genetics…”
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    Synaptic polarity of the interneuron circuit controlling C. elegans locomotion by Rakowski, Franciszek, Srinivasan, Jagan, Sternberg, Paul W, Karbowski, Jan

    Published in Frontiers in computational neuroscience (02-10-2013)
    “…Caenorhabditis elegans is the only animal for which a detailed neural connectivity diagram has been constructed. However, synaptic polarities in this diagram,…”
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  19. 19

    A comparison of experience-dependent locomotory behaviors and biogenic amine neurons in nematode relatives of Caenorhabditis elegans by Rivard, Laura, Srinivasan, Jagan, Stone, Allison, Ochoa, Stacy, Sternberg, Paul W, Loer, Curtis M

    Published in BMC neuroscience (19-02-2010)
    “…Survival of an animal depends on its ability to match its responses to environmental conditions. To generate an optimal behavioral output, the nervous system…”
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    The cGMP signaling pathway affects feeding behavior in the necromenic nematode Pristionchus pacificus by Kroetz, Silvina M, Srinivasan, Jagan, Yaghoobian, Jonathan, Sternberg, Paul W, Hong, Ray L

    Published in PloS one (26-04-2012)
    “…The genetic tractability and the species-specific association with beetles make the nematode Pristionchus pacificus an exciting emerging model organism for…”
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