Search Results - "Srinivas, Satish"
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An integrated investigation of structural and pathway alteration caused by PIK3CA and TP53 mutations identified in cfDNA of metastatic breast cancer
Published in Journal of cellular biochemistry (01-02-2023)“…In peripheral blood, cell‐free DNA (cfDNA) contains circulating tumor DNA (ctDNA), which indicates molecular abnormalities in metastatic breast tumor tissue…”
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Chromosome length ratio as a biomarker of DNA damage in cells exposed to high dose ionizing radiation
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01-07-2022)“…The premature chromosome condensation (PCC) assay is considered as complementary bio-dosimetry tool for chromosome aberration assay and the PCC assay can be…”
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Effect of turmeric supplementation on the pharmacokinetics of paclitaxel in breast cancer patients: A study with population pharmacokinetics approach
Published in Phytotherapy research (01-04-2022)“…Turmeric is one of the most used herbal supplements among cancer patients. It reportedly modulates the function of CYP450 enzymes and drug transporters. This…”
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Sox2 and Mitf cross-regulatory interactions consolidate progenitor and melanocyte lineages in the cranial neural crest
Published in Development (Cambridge) (15-01-2012)“…The cellular origin and molecular mechanisms regulating pigmentation of head and neck are largely unknown. Melanocyte specification is controlled by the…”
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Facile synthesis of elastin nanogels encapsulated decursin for castrated resistance prostate cancer therapy
Published in Scientific reports (02-07-2024)“…Nanogels offer hope for precise drug delivery, while addressing drug delivery hurdles is vital for effective prostate cancer (PCa) management. We developed an…”
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The targeted next-generation sequence revealed SMAD4, AKT1, and TP53 mutations from circulating cell-free DNA of breast cancer and its effect on protein structure - A computational approach
Published in Journal of biomolecular structure & dynamics (29-12-2023)“…Breast cancer biomarkers that detect marginally advanced stages are still challenging. The detection of specific abnormalities, targeted therapy selection,…”
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Assessment of different shielding materials for radiation therapy of maxillofacial tumors – An in vitro study
Published in The journal of Indian Prosthodontic Society (01-10-2024)“…Aim: Since the advent of radiotherapy, the success rate of head and neck cancer treatment has increased significantly. However, when the tissue tolerance level…”
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Development and Evaluation of the Psychometric Properties of the Tamil Version of Eating Assessment Tool − 10 (EAT-10): Preliminary Findings from Persons with Head and Neck Cancer
Published in Indian journal of otolaryngology, and head, and neck surgery (01-06-2023)“…Aims: This study aimed to develop and evaluate the psychometric properties of the Tamil version of the Eating Assessment Tool (EAT-10). Setting & Study Design:…”
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Deregulated Metabolic Pathways in Ovarian Cancer: Cause and Consequence
Published in Metabolites (01-04-2023)“…Ovarian cancers are tumors that originate from the different cells of the ovary and account for almost 4% of all the cancers in women globally. More than 30…”
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Etiological Profile and Clinico Epidemiological Patterns of Acute Encephalitis Syndrome in Tamil Nadu, India
Published in Journal of global infectious diseases (01-04-2023)“…Establishing the etiological cause of acute encephalitis syndrome (AES) is challenging due to the distinct distribution of various etiological agents. This…”
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Adenoid cystic carcinoma of the lacrimal gland in a child
Published in Pediatric hematology oncology journal (01-09-2023)Get full text
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Candidate Gene Expression in Regional Population and Its Relevance for Radiation Triage
Published in Cytogenetic and genome research (01-03-2024)“…Quantification of gene expression signatures has been substantiated as a potential and rapid marker for radiation triage and biodosimetry during nuclear…”
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13
Epitope identification and designing a potent multi-epitope vaccine construct against SARS-CoV-2 including the emerging variants
Published in Journal of global infectious diseases (01-01-2022)“…Introduction: The emergence of a novel coronavirus in China has turned into a SARS-CoV-2 pandemic with high fatality. As vaccines are developed through various…”
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Establishment of ex vivo calibration curve for X-ray induced “dicentric + ring” and micronuclei in human peripheral lymphocytes for biodosimetry during radiological emergencies, and validation with dose blinded samples
Published in Heliyon (01-06-2023)“…In the modern developing society, application of radiation has increased extensively. With significant improvement in the radiation protection practices,…”
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Impact of COVID-19 Pandemic on Patterns of Care and Outcome of Head and Neck Cancer: Real-World Experience From a Tertiary Care Cancer Center in India
Published in JCO global oncology (01-02-2022)“…The COVID-19 pandemic has caused unprecedented health, social, and economic unrest globally, particularly affecting resource-limited low-middle-income…”
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Distribution and Functional Analyses of Mutations in Spike Protein and Phylogenic Diversity of SARS-CoV-2 Variants Emerged during the Year 2021 in India
Published in Journal of global infectious diseases (01-04-2023)“…Prolonged COVID-19 pandemic accelerates the emergence and transmissibility of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants through the…”
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Prognostic significance of metabolic tumour volume and maximum standard uptake value of fluor-18-fluorodeoxyglucose positron emission tomography with computed tomography in nasopharyngeal carcinoma
Published in Contemporary oncology (Poznan, Poland) (01-01-2021)“…To evaluate the prognostic role of markers of fluor-18-fluorodeoxyglucose positron emission tomography with computed tomography ( F-FDG-PET-CT), such as…”
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Phylodynamic pattern of genetic clusters, paradigm shift on spatio-temporal distribution of clades, and impact of spike glycoprotein mutations of SARS-CoV-2 isolates from India
Published in Journal of global infectious diseases (01-10-2021)“…Introduction: The COVID-19 pandemic is associated with high morbidity and mortality, with the emergence of numerous variants. The dynamics of SARS-CoV-2 with…”
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Nimotuzumab with intensity-modulated radiation therapy in unresectable and platinum-ineligible locally advanced head-and-neck cancer
Published in South Asian journal of cancer (01-01-2020)“…Abstract Background: Outcomes with conventional treatment are poor in patients with squamous cell carcinoma of head and neck (SCCHN). Treatment options are…”
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Developmental toxicity of the environmental pollutant 4-nonylphenol in zebrafish
Published in Neurotoxicology and teratology (01-11-2011)“…Abstract 4-Nonylphenol (4-NP), an estrogen mimicking compound is produced by biodegradation of alkylethoxylates. It is well established that 4-NP can affect…”
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