Search Results - "Srilatha, Nonavinakere Seetharam"

Ter‐Seq: A high‐throughput method to stabilize transient ternary complexes and measure associated kinetics by Chattopadhyay, Gopinath, Ahmed, Shahbaz, Srilatha, Nonavinakere Seetharam, Asok, Aparna, Varadarajan, Raghavan

“…Regulation of biological processes by proteins often involves the formation of transient, multimeric complexes whose characterization is mechanistically…”
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Conformational Tuning Shapes the Balance between Functional Promiscuity and Specialization in Paralogous Plasmodium Acyl-CoA Binding Proteins by Dani, Rahul, Pawloski, Westley, Chaurasiya, Dhruv Kumar, Srilatha, Nonavinakere Seetharam, Agarwal, Sonal, Fushman, David, Naganathan, Athi N.

“…Paralogous proteins confer enhanced fitness to organisms via complex sequence–conformation codes that shape functional divergence, specialization, or…”
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Structure-based Design of Cyclically Permuted HIV-1 gp120 Trimers That Elicit Neutralizing Antibodies by Kesavardhana, Sannula, Das, Raksha, Citron, Michael, Datta, Rohini, Ecto, Linda, Srilatha, Nonavinakere Seetharam, DiStefano, Daniel, Swoyer, Ryan, Joyce, Joseph G., Dutta, Somnath, LaBranche, Celia C., Montefiori, David C., Flynn, Jessica A., Varadarajan, Raghavan

“…A major goal for HIV-1 vaccine development is an ability to elicit strong and durable broadly neutralizing antibody (bNAb) responses. The trimeric envelope…”
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Electrostatic interaction in BIAcore binding studies: A cause for anomaly by Srilatha, Nonavinakere Seetharam, Murthy, Gundlupet Satyanarayana

“…Sensograms of human chorionic gonadotropin–monoclonal antibody (hCG–MAb); ligand–ligate binding in the BIAcore were analysed. Surface-bound MAb in 0.1 M…”
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Epitope mapping from real time kinetic studies - role of crosslinked disulphides and incidental interacting regions in affinity measurements: study with human chorionic gonadotropin and monoclonal antibodies by Srilatha, Nonavinakere Seetharam, Selvi, P Tamil, Murthy, Gundlupet Satyanarayana

“…Real time kinetic studies were used to map conformational epitopes in human chorionic gonadotropin (hCG) for two monoclonal antibodies (MAbs). The epitopes…”
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Real-time kinetic analysis of hCG–monoclonal antibody interaction using radiolabeled hCG probe: presence of two forms of Ag–mAb complex as revealed by solid phase dissociation studies by Banerjee, Ashish, Srilatha, Nonavinakere Seetharam, Murthy, Gundlupet Satyanarayana

“…Real-time kinetics of ligand–ligate interaction has predominantly been studied by either fluorescence or surface plasmon resonance based methods. Almost all…”
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Epitope mapping from real time kinetic studies — Role of cross-linked disulphides and incidental interacting regions in affinity measurements: Study with human chorionic gonadotropin and monoclonal antibodies by Srilatha, Nonavinakere Seetharam, Selvi, P. Tamil, Murthy, Gundlupet Satyanarayana

“…Real time kinetic studies were used to map conformational epitopes in human chorionic gonadotropin (hCG) for two monoclonal antibodies (MAbs). The epitopes…”
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