Search Results - "Sridharan, Gautham V"

Gut Microbiota-Derived Tryptophan Metabolites Modulate Inflammatory Response in Hepatocytes and Macrophages by Krishnan, Smitha, Ding, Yufang, Saedi, Nima, Choi, Maria, Sridharan, Gautham V., Sherr, David H., Yarmush, Martin L., Alaniz, Robert C., Jayaraman, Arul, Lee, Kyongbum

“…The gut microbiota plays a significant role in the progression of fatty liver disease; however, the mediators and their mechanisms remain to be elucidated…”
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Prediction and quantification of bioactive microbiota metabolites in the mouse gut by Sridharan, Gautham V., Choi, Kyungoh, Klemashevich, Cory, Wu, Charmian, Prabakaran, Darshan, Pan, Long Bin, Steinmeyer, Shelby, Mueller, Carrie, Yousofshahi, Mona, Alaniz, Robert C., Lee, Kyongbum, Jayaraman, Arul

“…Metabolites produced by the intestinal microbiota are potentially important physiological modulators. Here we present a metabolomics strategy that models…”
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Quantitative metabolic imaging using endogenous fluorescence to detect stem cell differentiation by Quinn, Kyle P., Sridharan, Gautham V., Hayden, Rebecca S., Kaplan, David L., Lee, Kyongbum, Georgakoudi, Irene

“…The non-invasive high-resolution spatial mapping of cell metabolism within tissues could provide substantial advancements in assessing the efficacy of stem…”
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Metabolic profiling during ex vivo machine perfusion of the human liver by Bruinsma, Bote G., Sridharan, Gautham V., Weeder, Pepijn D., Avruch, James H., Saeidi, Nima, Özer, Sinan, Geerts, Sharon, Porte, Robert J., Heger, Michal, van Gulik, Thomas M., Martins, Paulo N., Markmann, James F., Yeh, Heidi, Uygun, Korkut

“…As donor organ shortages persist, functional machine perfusion is under investigation to improve preservation of the donor liver. The transplantation of…”
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Elevated homocysteine is negatively correlated with plasma cystathionine β‐synthase activity in givosiran‐treated patients by Keibler, Mark A., Sridharan, Gautham V., Sweetser, Marianne T., Ticau, Simina

“…Givosiran is a subcutaneously administered, liver‐targeted RNA interference (RNAi) therapeutic that has been approved for treating acute hepatic porphyria…”
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Analysis of transcription factor network underlying 3T3-L1 adipocyte differentiation by Choi, KyungOh, Ghaddar, Bassel, Moya, Colby, Shi, Hai, Sridharan, Gautham V, Lee, Kyongbum, Jayaraman, Arul

“…Lipid accumulation in adipocytes reflects a balance between enzymatic pathways leading to the formation and breakdown of esterified lipids, primarily…”
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Neurofilament Light Chain as a Biomarker of Hereditary Transthyretin-Mediated Amyloidosis by Ticau, Simina, Sridharan, Gautham V., Tsour, Shira, Cantley, William L., Chan, Amy, Gilbert, Jason A., Erbe, David, Aldinc, Emre, Reilly, Mary M., Adams, David, Polydefkis, Michael, Fitzgerald, Kevin, Vaishnaw, Akshay, Nioi, Paul

“…OBJECTIVETo identify changes in the proteome associated with onset and progression of ATTRv amyloidosis, we performed an observational, case-controlled study…”
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Lysyl oxidase-mediated collagen crosslinks may be assessed as markers of functional properties of tendon tissue formation by Marturano, Joseph E., Xylas, Joanna F., Sridharan, Gautham V., Georgakoudi, Irene, Kuo, Catherine K.

“…Mechanical property elaboration of engineered tissues is often assumed on the basis of gene and protein characterizations, rather than mechanical testing…”
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Gut Microbiota-Derived Tryptophan Metabolites Modulate Inflammatory Response in Hepatocytes and Macrophages by Krishnan, Smitha, Ding, Yufang, Saeidi, Nima, Choi, Maria, Sridharan, Gautham V., Sherr, David H., Yarmush, Martin L., Alaniz, Robert C., Jayaraman, Arul, Lee, Kyongbum

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Peritransplant Energy Changes and Their Correlation to Outcome After Human Liver Transplantation by Bruinsma, Bote G, Avruch, James H, Sridharan, Gautham V, Weeder, Pepijn D, Jacobs, Marie Louise, Crisalli, Kerry, Amundsen, Beth, Porte, Robert J, Markmann, James F, Uygun, Korkut, Yeh, Heidi

“…BACKGROUNDThe ongoing shortage of donor livers for transplantation and the increased use of marginal livers necessitate the development of accurate…”
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Functional human liver preservation and recovery by means of subnormothermic machine perfusion by Bruinsma, Bote G, Avruch, James H, Weeder, Pepijn D, Sridharan, Gautham V, Uygun, Basak E, Karimian, Negin G, Porte, Robert J, Markmann, James F, Yeh, Heidi, Uygun, Korkut

“…There is currently a severe shortage of liver grafts available for transplantation. Novel organ preservation techniques are needed to expand the pool of donor…”
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Functional Human Liver Preservation and Recovery by Means of Subnormothermic Machine Perfusion by Bruinsma, Bote G., Avruch, James H., Weeder, Pepijn D., Sridharan, Gautham V., Uygun, Basak E., Karimian, Negin G., Porte, Robert J., Markmann, James F., Yeh, Heidi, Uygun, Korkut

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Analysis of Transcription Factor Network Underlying 3T3-L1 Adipocyte Differentiation: e100177 by Choi, KyungOh, Ghaddar, Bassel, Moya, Colby, Shi, Hai, Sridharan, Gautham V, Lee, Kyongbum, Jayaraman, Arul

“…Lipid accumulation in adipocytes reflects a balance between enzymatic pathways leading to the formation and breakdown of esterified lipids, primarily…”
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