Search Results - "Sridhar, Shaarwari"

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    879 A promising cancer immunotherapy target: novel fully human agonist antibodies against the human T-cell costimulatory receptor CD27 by Guillaudeux, Thierry, Ovechkina, Yulia, Sridhar, Shaarwari, Jurchen, David, Peckham, David, Frazier, Emily, Tarcha, Eric, Iadonato, Shawn

    Published in Journal for immunotherapy of cancer (01-11-2021)
    “…BackgroundCD27 is a member of the TNF receptor superfamily and plays a critical role in T-cell activation by providing a costimulatory signal. CD27 signaling…”
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    Journal Article
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    VISTA a Potential New Immuno-Oncology Target in Acute Myeloid Leukemia by Guillaudeux, Thierry, Sridhar, Shaarwari, Frazier, Emily, Ovechkina, Yulia, Iadonato, Shawn

    Published in Blood (02-11-2023)
    “…V-domain Immunoglobulin Suppressor of T cell Activation (VISTA/PD-1H) is a B7 family member highly expressed on circulating and intra-tumoral myeloid cells…”
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    Journal Article
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    Abstract P21: VISTA a potential new Immuno-oncology therapeutic target to treat human Acute Myeloid Leukemia by Guillaudeux, Thierry, Sridhar, Shaarwari, Frazier, Emily, Ovechkina, Yulia, Iadonato, Shawn

    Published in Blood cancer discovery (04-03-2024)
    “…Abstract V-domain Immunoglobulin Suppressor of T cell Activation (VISTA/PD-1H) is a co-inhibitor molecule of the B7 family member highly expressed on…”
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    Journal Article
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    Abstract 4261: CD27 a new immuno-oncology target shaping innate and adaptive anti-tumor immune responses by Guillaudeux, Thierry, Ovechkina, Yulia, Sridhar, Shaarwari, Peckham, David, Cross, Jessica, Eyde, Nathan, Frazier, Emily, Kabi, Neda, Lance, Remington, Lustig, Kurt, Xu, Mei, Eric, Tarcha, Iadonato, Shawn

    Published in Cancer research (Chicago, Ill.) (15-06-2022)
    “…Abstract CD27 is a member of the TNF-receptor superfamily, highly expressed on CD4+ and CD8+ T cells as well as on NK and NKT cells. It plays a key role on T…”
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    Journal Article
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