Search Results - "Sridhar, Radhakrishnan"

Electrosprayed nanoparticles and electrospun nanofibers based on natural materials: applications in tissue regeneration, drug delivery and pharmaceuticals by Sridhar, Radhakrishnan, Lakshminarayanan, Rajamani, Madhaiyan, Kalaipriya, Amutha Barathi, Veluchamy, Lim, Keith Hsiu Chin, Ramakrishna, Seeram

“…Nanotechnology refers to the fabrication, characterization, and application of substances in nanometer scale dimensions for various ends. The influence of…”
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Resveratrol suppresses IGF-1 induced human colon cancer cell proliferation and elevates apoptosis via suppression of IGF-1R/Wnt and activation of p53 signaling pathways by Vanamala, Jairam, Reddivari, Lavanya, Radhakrishnan, Sridhar, Tarver, Chris

“…Obesity is a global phenomenon and is associated with various types of cancer, including colon cancer. There is a growing interest for safe and effective…”
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Review: the characterization of electrospun nanofibrous liquid filtration membranes by Kaur, Satinderpal, Sundarrajan, Subramanian, Rana, Dipak, Sridhar, Radhakrishnan, Gopal, Renuga, Matsuura, Takeshi, Ramakrishna, Seeram

“…Electrospun nanofibrous membranes (ENMs) are used in a variety of applications, including sensors, tissue engineering, air filtration, energy, and…”
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Gold Nanoparticle Loaded Hybrid Nanofibers for Cardiogenic Differentiation of Stem Cells for Infarcted Myocardium Regeneration by Ravichandran, Rajeswari, Sridhar, Radhakrishnan, Venugopal, Jayarama Reddy, Sundarrajan, Subramanian, Mukherjee, Shayanti, Ramakrishna, Seeram

“…Heart disease is the leading cause of mortality in many industrialized nations and is often related to irregularities in electrical function that can radically…”
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Protecting infrastructure performance from disinformation attacks by Jamalzadeh, Saeed, Barker, Kash, González, Andrés D., Radhakrishnan, Sridhar

“…Disinformation campaigns are prevalent, affecting vaccination coverage, creating uncertainty in election results, and causing supply chain disruptions, among…”
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Current Challenges in Small Molecule Proximity-Inducing Compound Development for Targeted Protein Degradation Using the Ubiquitin Proteasomal System by Radhakrishnan, Sridhar, Hoff, Oskar, Muellner, Markus K

“…Bivalent proximity-inducing compounds represent a novel class of small molecule therapeutics with exciting potential and new challenges. The most prominent…”
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Nanofibrous structured biomimetic strategies for skin tissue regeneration by Jayarama Reddy, Venugopal, Radhakrishnan, Sridhar, Ravichandran, Rajeswari, Mukherjee, Shayanti, Balamurugan, Ramalingam, Sundarrajan, Subramanian, Ramakrishna, Seeram

“…Mimicking porous topography of natural extracellular matrix is advantageous for successful regeneration of damaged tissues or organs. Nanotechnology being one…”
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A new protocol to synthesize 1,4-dihydropyridines by using 3,4,5-trifluorobenzeneboronic acid as a catalyst in ionic liquid: synthesis of novel 4-(3-carboxyl-1 H-pyrazol-4-yl)-1,4-dihydropyridines by Sridhar, Radhakrishnan, Perumal, Paramasivan T.

“…3,4,5-Trifluorobenzeneboronic acid catalysed, ionic liquid mediated facile synthesis of 4-pyrazolyl 1,4-dihydropyridines at room temperature by the…”
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Maintaining the Giant Component in Networks With Edge Weighted Augmentation Given Causal Failures by Zhang, Zuyuan, Radhakrishnan, Sridhar, Barker, Kash, Gonzalez, Andres D.

“…Understanding the relationship between various nodes of a network is critical for building a robust and resilient network. Studying and understanding the…”
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Hybrid PMC (HPMC) fault model and diagnosability of interconnection networks by Zhu, Qiang, Thulasiraman, Krishnaiyan, Xu, Min, Radhakrishnan, Sridhar

“…System level diagnosis, an area pioneered by Preparata, Metze and Chien, has been a dominant area of research in the broader area of fault-tolerant computing…”
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Targeted Protein Degradation: An Important Tool for Drug Discovery for “Undruggable” Tumor Transcription Factors by Dai, Mengyuan, Radhakrishnan, Sridhar, Li, Rui, Tan, Ruirong, Yan, Kuo, Fan, Gang, Liu, Miao

“…Conventional small-molecule drugs (SMDs) are compounds characterized by low molecular weight, high cell permeability, and high selectivity. In clinical…”
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Colon carcinogenesis: Influence of Western diet-induced obesity and targeting stem cells using dietary bioactive compounds by Kasdagly, Maria, M.S, Radhakrishnan, Sridhar, Ph.D, Reddivari, Lavanya, Ph.D, Veeramachaneni, D.N. Rao, B.V.Sc., M.Sc.Vet., Ph.D, Vanamala, Jairam, Ph.D

“…Abstract Colon cancer strikes more than 1 million people annually and is responsible for more than 500,000 cancer deaths worldwide. Recent evidence suggests…”
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Interaction of gelatin with polyenes modulates antifungal activity and biocompatibility of electrospun fiber mats by Lakshminarayanan, Rajamani, Sridhar, Radhakrishnan, Loh, Xian Jun, Nandhakumar, Muruganantham, Barathi, Veluchamy Amutha, Kalaipriya, Madhaiyan, Kwan, Jia Lin, Liu, Shou Ping, Beuerman, Roger Wilmer, Ramakrishna, Seeram

“…Topical application of antifungals does not have predictable or well-controlled release characteristics and requires reapplication to achieve therapeutic local…”
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Indian gooseberry (Emblica officinalis Gaertn.) suppresses cell proliferation and induces apoptosis in human colon cancer stem cells independent of p53 status via suppression of c-Myc and cyclin D1 by Vadde, Ramakrishna, Radhakrishnan, Sridhar, Eranda Karunathilake Kurundu, Hewage, Reddivari, Lavanya, Vanamala, Jairam K.P.

“…•Indian gooseberry (amla) is rich in bioactive compounds including trigonelline, naringin, catechin, quercetin and kaempferol.•Amla suppressed proliferation…”
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Styryl Quinazolinones as Potential Inducers of Myeloid Differentiation via Upregulation of C/EBPα by Sridhar, Radhakrishnan, Takei, Hisashi, Syed, Riyaz, Kobayashi, Ikei S, Hui, Liu Bee, Kamal, Ahmed, Tenen, Daniel G, Kobayashi, Susumu S

“…The CCAAT enhancer-binding protein α (C/EBPα) plays an important role in myeloid cell differentiation and in the enhancement of C/EBPα expression/activity,…”
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Neurophysiology of spontaneous facial expressions: I. Motor control of the upper and lower face is behaviorally independent in adults by Ross, Elliott D., Gupta, Smita S., Adnan, Asif M., Holden, Thomas L., Havlicek, Joseph, Radhakrishnan, Sridhar

“…Facial expressions are described traditionally as monolithic entities. However, humans have the capacity to produce facial blends, in which the upper and lower…”
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A Translational Mouse Model for NASH with Advanced Fibrosis and Atherosclerosis Expressing Key Pathways of Human Pathology by van den Hoek, Anita M, Verschuren, Lars, Worms, Nicole, van Nieuwkoop, Anita, de Ruiter, Christa, Attema, Joline, Menke, Aswin L, Caspers, Martien P M, Radhakrishnan, Sridhar, Salic, Kanita, Kleemann, Robert

“…Non-alcoholic steatohepatitis (NASH) is a fast-growing liver disorder that is associated with an increased incidence of cardiovascular disease and type 2…”
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Design, synthesis and anti-microbial activity of 1H-pyrazole carboxylates by SRIDHAR, Radhakrishnan, PERUMAL, Paramasivam T, ETTI, Sundaresan, SHANMUGAM, Guruswamy, PONNUSWAMY, Mondikalipudur N, PRABAVATHY, Vaiyapuri R, MATHIVANAN, Narayanasamy

“…In a SAR study, we have synthesized a few 1H-pyrazole carboxylate related microbicides using Vilsmeier reagent. The anti-microbial screening results of…”
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Resveratrol suppresses human colon cancer cell proliferation and induces apoptosis via targeting the pentose phosphate and the talin-FAK signaling pathways-A proteomic approach by Vanamala, Jairam, Radhakrishnan, Sridhar, Reddivari, Lavanya, Bhat, Vadiraja B, Ptitsyn, Andrey

“…We and others have previously reported that resveratrol (RSV) suppresses colon cancer cell proliferation and elevates apoptosis in vitro and/or in vivo,…”
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Medical devices regulatory aspects: a special focus on polymeric material based devices by Sridhar, Radhakrishnan, Pliszka, Damian, Luo, He-Kuan, Chin Lim, Keith Hsiu, Ramakrishna, Seeram

“…Medical devices form a broad range of appliances from a basic nanoparticle coating or surgical gloves to a complicated laser therapy device. These devices are…”
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