Search Results - "Sridhar, Harsha"

SMARCA4 controls state plasticity in small cell lung cancer through regulation of neuroendocrine transcription factors and REST splicing by Redin, Esther, Sridhar, Harsha, Zhan, Yingqian A, Pereira Mello, Barbara, Zhong, Hong, Durani, Vidushi, Sabet, Amin, Manoj, Parvathy, Linkov, Irina, Qiu, Juan, Koche, Richard P, de Stanchina, Elisa, Astorkia, Maider, Betel, Doron, Quintanal-Villalonga, Álvaro, Rudin, Charles M

“…Small Cell Lung Cancer (SCLC) can be classified into transcriptional subtypes with distinct degrees of neuroendocrine (NE) differentiation. Recent evidence…”
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Correction: SMARCA4 controls state plasticity in small cell lung cancer through regulation of neuroendocrine transcription factors and REST splicing by Redin, Esther, Sridhar, Harsha, Zhan, Yingqian A, Pereira Mello, Barbara, Zhong, Hong, Durani, Vidushi, Sabet, Amin, Manoj, Parvathy, Linkov, Irina, Qiu, Juan, Koche, Richard P, de Stanchina, Elisa, Astorkia, Maider, Betel, Doron, Quintanal-Villalonga, Álvaro, Rudin, Charles M

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CDC7 inhibition impairs neuroendocrine transformation in lung and prostate tumors through MYC degradation by Quintanal-Villalonga, Alvaro, Kawasaki, Kenta, Redin, Esther, Uddin, Fathema, Rakhade, Swanand, Durani, Vidushi, Sabet, Amin, Shafer, Moniquetta, Karthaus, Wouter R., Zaidi, Samir, Zhan, Yingqian A., Manoj, Parvathy, Sridhar, Harsha, Kinyua, Dennis, Zhong, Hong, Mello, Barbara P., Ciampricotti, Metamia, Bhanot, Umesh K., Linkov, Irina, Qiu, Juan, Patel, Radhika A., Morrissey, Colm, Mehta, Sanjoy, Barnes, Jesse, Haffner, Michael C., Socci, Nicholas D., Koche, Richard P., de Stanchina, Elisa, Molina-Pinelo, Sonia, Salehi, Sohrab, Yu, Helena A., Chan, Joseph M., Rudin, Charles M.

“…Neuroendocrine (NE) transformation is a mechanism of resistance to targeted therapy in lung and prostate adenocarcinomas leading to poor prognosis. Up to date,…”
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The ectonucleotidase CD39 identifies tumor-reactive CD8+ T cells predictive of immune checkpoint blockade efficacy in human lung cancer by Chow, Andrew, Uddin, Fathema Z., Liu, Michael, Dobrin, Anton, Nabet, Barzin Y., Mangarin, Levi, Lavin, Yonit, Rizvi, Hira, Tischfield, Sam E., Quintanal-Villalonga, Alvaro, Chan, Joseph M., Shah, Nisargbhai, Allaj, Viola, Manoj, Parvathy, Mattar, Marissa, Meneses, Maximiliano, Landau, Rebecca, Ward, Mariana, Kulick, Amanda, Kwong, Charlene, Wierzbicki, Matthew, Yavner, Jessica, Egger, Jacklynn, Chavan, Shweta S., Farillas, Abigail, Holland, Aliya, Sridhar, Harsha, Ciampricotti, Metamia, Hirschhorn, Daniel, Guan, Xiangnan, Richards, Allison L., Heller, Glenn, Mansilla-Soto, Jorge, Sadelain, Michel, Klebanoff, Christopher A., Hellmann, Matthew D., Sen, Triparna, de Stanchina, Elisa, Wolchok, Jedd D., Merghoub, Taha, Rudin, Charles M.

“…Improved identification of anti-tumor T cells is needed to advance cancer immunotherapies. CD39 expression is a promising surrogate of tumor-reactive CD8+…”
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Exportin 1 inhibition prevents neuroendocrine transformation through SOX2 down-regulation in lung and prostate cancers by Quintanal-Villalonga, Alvaro, Durani, Vidushi, Sabet, Amin, Redin, Esther, Kawasaki, Kenta, Shafer, Moniquetta, Karthaus, Wouter R, Zaidi, Samir, Zhan, Yingqian A, Manoj, Parvathy, Sridhar, Harsha, Shah, Nisargbhai S, Chow, Andrew, Bhanot, Umesh K, Linkov, Irina, Asher, Marina, Yu, Helena A, Qiu, Juan, de Stanchina, Elisa, Patel, Radhika A, Morrissey, Colm, Haffner, Michael C, Koche, Richard P, Sawyers, Charles L, Rudin, Charles M

“…In lung and prostate adenocarcinomas, neuroendocrine (NE) transformation to an aggressive derivative resembling small cell lung cancer (SCLC) is associated…”
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Abstract 2004: CDC7 inhibition prevents neuroendocrine transformation in the lung and prostate through MYC degradation by Quintanal-Villalonga, Alvaro, Uddin, Fathema, Kawasaki, Kenta, Redin, Esther, Durani, Vidushi, Sabet, Amin, Karthaus, Wouter, Zhan, Yingqian A., Zaidi, Samir, Shaffer, Moniquetta, Sridhar, Harsha, Qiu, Juan, Manoj, Parvathy, De Stanchina, Elisa, Haffner, Michael C., Sawyers, Charles L., Rudin, Charles M.

“…Abstract Neuroendocrine (NE) transformation occurs as a mechanism of resistance to targeted therapy in up to 14% and 30% of EGFR-mutant lung and AR-dependent…”
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Abstract 3858: Exploring Exportin-1 as a therapeutic vulnerability in squamous cell carcinoma by Durani, Vidushi, Caeser, Rebecca, Rudin, Charles M., Quintanal-Villalonga, Alvaro, Sridhar, Harsha, Manoj, Parvathy, Tischfield, Sam E., Asher, Marina, Bhanot, Umeshkumar, Egger, Jacklynn V., Socci, Nicholas D. Socci D., Shah, Nisargbhai S S., de Stanchina, Elisa, Rekhtman, Natasha

“…Abstract Introduction: Squamous cell carcinomas (LUSCs) account for 25-30% cases of non-small cell lung cancers, making them the second most common histology…”
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Segmentation of Blood Vessels by Local Analysis of 2D Image Patches by Sridhar, Harsha, Kumar, J. R. Harish

“…Retinal vasculature can be considered a major indicator of various opthalmologic disorders and diseases. Therefore, it is important to accurately detect and…”
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Route-metric-based dynamic routing and wavelength assignment for multifiber WDM networks by Jong-Seon Kim, Lee, D.C., Sridhar, H.

“…We present three dynamic routing and wavelength assignment (RWA) algorithms that are intended for multifiber WDM networks without wavelength converters. For…”
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AN UNCONSTRAINED ELLIPSE FITTING TECHNIQUE AND APPLICATION TO OPTIC CUP SEGMENTATION by Sridhar, Harsha, Harish Kumar, J. R., Jois, Subramanya, Seelamantula, Chandra Sekhar

“…We present a novel method for fitting an ellipse to scattered data based on least-squares minimization. The new technique has several advantages over the…”
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A FULLY AUTOMATED SPINAL CORD SEGMENTATION by Subramanya Jois, S. P., Sridhar, Harsha, Harish Kumar, J. R.

“…Segmentation of the spinal cord region is an imperative step in the automated analysis of neurological ailments such as multiple sclerosis. Multiple studies…”
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