A chemoenzymatic synthesis of 3,4,5,6-tetrahydro-2H-benzo[b][1,4]-oxazocine-3,5-dione and its derivatives

The enzymatic cyclization of phenoxyacetylcyanomethylenetriphenylphosphorane derivatives using pre-treated baker’s yeast cells, a rapid one-pot assembly of heteromacrocyclic compounds, is described. Graphical abstract

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Bibliographic Details
Published in:	Monatshefte für Chemie Vol. 140; no. 6; pp. 611 - 613
Main Authors:	Sree Lakshmi, Ch, Rehaman, H., Rao, Adari Bhaskar
Format:	Journal Article
Language:	English
Published:	Vienna Springer Vienna 01-06-2009
Subjects:	Analytical Chemistry Chemistry Chemistry and Materials Science Chemistry/Food Science Inorganic Chemistry Organic Chemistry Original Paper Physical Chemistry Theoretical and Computational Chemistry Macrocyclic Green chemistry Baker’s yeast Cyclization Aqueous medium
Online Access:	Get full text
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Description
Summary:	The enzymatic cyclization of phenoxyacetylcyanomethylenetriphenylphosphorane derivatives using pre-treated baker’s yeast cells, a rapid one-pot assembly of heteromacrocyclic compounds, is described. Graphical abstract
ISSN:	0026-9247 1434-4475
DOI:	10.1007/s00706-008-0101-7