Search Results - "Sram, R.J"

Transcriptome alterations in maternal and fetal cells induced by tobacco smoke by Votavova, H, Dostalova Merkerova, M, Fejglova, K, Vasikova, A, Krejcik, Z, Pastorkova, A, Tabashidze, N, Topinka, J, Veleminsky, M, Sram, R.J, Brdicka, R

“…Abstract Objectives Maternal smoking has a negative effect on all stages of pregnancy. Tobacco smoke-related defects are well established at the clinical…”
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Effect of Maternal Tobacco Smoke Exposure on the Placental Transcriptome by Bruchova, H, Vasikova, A, Merkerova, M, Milcova, A, Topinka, J, Balascak, I, Pastorkova, A, Sram, R.J, Brdicka, R

“…Abstract Smoking in pregnancy increases a woman's risk of preterm delivery resulting in serious neonatal health problems and chronic lifelong disabilities for…”
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Temporal variation in the genotoxic potential of urban air particulate matter by Sevastyanova, O., Novakova, Z., Hanzalova, K., Binkova, B., Sram, R.J., Topinka, J.

“…The main aim of this study was to compare the genotoxic potential of organic extracts from urban air particles collected in three different sampling periods in…”
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In vitro genotoxicity of PAH mixtures and organic extract from urban air particles by Sevastyanova, O, Binkova, B, Topinka, J, Sram, R J, Kalina, I, Popov, T, Novakova, Z, Farmer, P B

“…Principal aims of this study were at first, to find a relevant human derived cell line to investigate the genotoxic potential of PAH-containing complex…”
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Chromosomal aberrations in peripheral lymphocytes of children as biomarkers of environmental exposure and life style by Rössner, P, Bavorova, H, Ocadlikova, D, Svandova, E, Sram, R.J

“…The original purpose of our study was to determine if the detection of chromosomal aberrations in peripheral lymphocytes of children might be used as a…”
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Chromosomal aberrations and SCEs as biomarkers of cancer risk by Norppa, H, Bonassi, S, Hansteen, I-L, Hagmar, L, Strömberg, U, Rössner, P, Boffetta, P, Lindholm, C, Gundy, S, Lazutka, J, Cebulska-Wasilewska, A, Fabiánová, E, Srám, R J, Knudsen, L E, Barale, R, Fucic, A

“…Previous studies have suggested that the frequency of chromosomal aberrations (CAs), but not of sister chromatid exchanges (SCEs), predicts cancer risk. We…”
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The impact of air pollution on the levels of micronuclei measured by automated image analysis by Rossnerova, A, Spatova, M, Rossner, P, Solansky, I, Sram, R J

“…The measurement of micronuclei (MN) in human peripheral blood lymphocytes is frequently used in molecular epidemiology as one of the preferred methods for…”
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Genetic polymorphisms influence the susceptibility of men to sperm DNA damage associated with exposure to air pollution by Rubes, J, Rybar, R, Prinosilova, P, Veznik, Z, Chvatalova, I, Solansky, I, Sram, R J

“…The purpose of the present study was to investigate the impact of carcinogenic polycyclic aromatic hydrocarbons and volatile organic compounds on sperm quality…”
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Biomarkers of air pollution exposure--a study of policemen in Prague by Topinka, J, Sevastyanova, O, Binkova, B, Chvatalova, I, Milcova, A, Lnenickova, Z, Novakova, Z, Solansky, I, Sram, R J

“…The effect of exposure to organic compounds adsorbed onto respirable air particles (<2.5microm) on DNA adducts in lymphocytes was studied in a group of…”
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Frequency of chromosomal aberrations in Prague mothers and their newborns by Rossnerova, A., Balascak, I., Rossner, P., Sram, R.J.

“…The capital city of Prague is one of the most polluted areas of the Czech Republic. The impact of air pollution on the level of chromosomal aberrations was…”
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Effect of vitamin levels on biomarkers of exposure and oxidative damage—The EXPAH study by Sram, R.J., Farmer, P., Singh, R., Garte, S., Kalina, I., Popov, T.A., Binkova, B., Ragin, C., Taioli, E.

“…DNA adducts are markers of carcinogen exposure and of their biological effect; they have been shown to be related to mutagenesis, and therefore they could be a…”
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The use of biomarkers for risk assessment: Reporting from the INTARESE/ENVIRISK Workshop in Prague by Smolders, R., Bartonova, A., Boogaard, P.J., Dusinska, M., Koppen, G., Merlo, F., Sram, R.J., Vineis, P., Schoeters, G.

“…This publication is a report on the workshop “The use of biomarkers for risk assessment” which took place in November 2007 in Prague, the Czech Republic. The…”
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Genome-wide differential gene expression in children exposed to air pollution in the Czech Republic by van Leeuwen, D M, van Herwijnen, M H M, Pedersen, M, Knudsen, L E, Kirsch-Volders, M, Sram, R J, Staal, Y C M, Bajak, E, van Delft, J H M, Kleinjans, J C S

“…The Teplice area in the Czech Republic is a mining district where elevated levels of air pollution including airborne carcinogens, have been demonstrated,…”
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Coal Home Heating and Environmental Tobacco Smoke in Relation to Lower Respiratory Illness in Czech Children, from Birth to 3 Years of Age by Baker, Rebecca J., Hertz-Picciotto, Irva, Dostál, Miroslav, Keller, Jean A., Nožička, Jiři, Kotěšovec, František, Dejmek, Jan, Loomis, Dana, Šrám, Radim J.

“…Objective: The objective of this study was to evaluate how indoor pollution from tobacco and home heating may adversely affect respiratory health in young…”
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Biological effect monitoring in industrial workers from the Czech Republic exposed to low levels of butadiene by Tates, A.D., van Dam, F.J., de Zwart, F.A., Darroudi, F., Natarajan, A.T., Rössner, P., Peterková, K., Peltonen, K., Demopoulos, N.A., Stephanou, G., Vlachodimitropoulos, D., Srám, R.J.

“…Blood samples were collected twice (in 1993 and 1994) from 19 workers exposed to 1,3-butadiene and 19 matched controls. Three exposed and three control…”
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Hemoglobin adducts of epoxybutene in workers occupationally exposed to 1,3-butadiene by BEGEMANN, P, SRAM, R. J, NEUMANN, H.-G

“…1,3-Butadiene (BD) is an important chemical widely used in the synthetic rubber industry. Hemoglobin adducts of two of its reactive metabolites have been…”
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Infiltration of ambient PM 2.5 and levels of indoor generated non-ETS PM 2.5 in residences of four European cities by Hänninen, O.O., Lebret, E., Ilacqua, V., Katsouyanni, K., Künzli, N., Srám, R.J., Jantunen, M.

“…Ambient fine particle (PM 2.5) concentrations are associated with premature mortality and other health effects. Urban populations spend a majority of their…”
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In vitro genotoxicity of PAH mixtures and organic extract from urban air particles by Binkova, B, Topinka, J, Sram, R J, Sevastyanova, O, Novakova, Z, Schmuczerova, J, Kalina, I, Popov, T, Farmer, P B

“…Acellular assay of calf thymus DNA+/-rat liver microsomal S9 fraction coupled with super(3) super(2)P-postlabelling was used to study the genotoxic potential…”
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589 PAH-DNA adducts in environmentally exposed population in relation to metabolic and DNA repair genes polymorphisms by Binkova, B., Smerhovsky, Z., Chvatalova, I., Biros, E., Stavkova, Z., Milcova, A., Sram, R.J.

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Mutagenicity, carcinogenicity, and teratogenicity of acrylonitrile by Léonard, A, Gerber, G.B, Stecca, C, Rueff, J, Borba, H, Farmer, P.B, Sram, R.J, Czeizel, A.E, Kalina, I

“…Acrylonitrile (AN) is an important intermediary for the synthesis of a variety of organic products, such as artificial fibres, household articles and resins…”
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