Search Results - "Squirrell, Jayne M"

Matrix metalloproteinase 9 modulates collagen matrices and wound repair by LeBert, Danny C, Squirrell, Jayne M, Rindy, Julie, Broadbridge, Elizabeth, Lui, Yuming, Zakrzewska, Anna, Eliceiri, Kevin W, Meijer, Annemarie H, Huttenlocher, Anna

“…Acute and chronic injuries are characterized by leukocyte infiltration into tissues. Although matrix metalloproteinase 9 (Mmp9) has been implicated in both…”
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Lineage Reprogramming of Fibroblasts into Proliferative Induced Cardiac Progenitor Cells by Defined Factors by Lalit, Pratik A., Salick, Max R., Nelson, Daryl O., Squirrell, Jayne M., Shafer, Christina M., Patel, Neel G., Saeed, Imaan, Schmuck, Eric G., Markandeya, Yogananda S., Wong, Rachel, Lea, Martin R., Eliceiri, Kevin W., Hacker, Timothy A., Crone, Wendy C., Kyba, Michael, Garry, Daniel J., Stewart, Ron, Thomson, James A., Downs, Karen M., Lyons, Gary E., Kamp, Timothy J.

“…Several studies have reported reprogramming of fibroblasts into induced cardiomyocytes; however, reprogramming into proliferative induced cardiac progenitor…”
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Damage-induced reactive oxygen species regulate vimentin and dynamic collagen-based projections to mediate wound repair by LeBert, Danny, Squirrell, Jayne M, Freisinger, Chrissy, Rindy, Julie, Golenberg, Netta, Frecentese, Grace, Gibson, Angela, Eliceiri, Kevin W, Huttenlocher, Anna

“…Tissue injury leads to early wound-associated reactive oxygen species (ROS) production that mediate tissue regeneration. To identify mechanisms that function…”
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Cortical granule exocytosis in C. elegans is regulated by cell cycle components including separase by Bembenek, Joshua N, Richie, Christopher T, Squirrell, Jayne M, Campbell, Jay M, Eliceiri, Kevin W, Poteryaev, Dmitry, Spang, Anne, Golden, Andy, White, John G

“…In many organisms, cortical granules undergo exocytosis following fertilization, releasing cargo proteins that modify the extracellular covering of the zygote…”
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Distinct Tissue Damage and Microbial Cues Drive Neutrophil and Macrophage Recruitment to Thermal Injury by Barros-Becker, Francisco, Squirrell, Jayne M., Burke, Russell, Chini, Julia, Rindy, Julie, Karim, Aos, Eliceiri, Kevin W., Gibson, Angela, Huttenlocher, Anna

“…Tissue damage triggers a rapid innate immune response that mediates host defense. Previously we reported that thermal damage of the larval zebrafish fin…”
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Image-inspired 3D multiphoton excited fabrication of extracellular matrix structures by modulated raster scanning by Ajeti, Visar, Lien, Chi-Hsiang, Chen, Shean-Jen, Su, Ping-Jung, Squirrell, Jayne M, Molinarolo, Katharine H, Lyons, Gary E, Eliceiri, Kevin W, Ogle, Brenda M, Campagnola, Paul J

“…Multiphoton excited photochemistry is a powerful 3D fabrication tool that produces sub-micron feature sizes. Here we exploit the freeform nature of the process…”
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Long-term two-photon fluorescence imaging of mammalian embryos without compromising viability by Squirrell, Jayne M, Wokosin, David L, White, John G, Bavister, Barry D

“…A major challenge for fluorescence imaging of living mammalian cells is maintaining viability following prolonged exposure to excitation illumination. We have…”
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Endogenous fluorescence signatures in living pluripotent stem cells change with loss of potency by Squirrell, Jayne M, Fong, Jimmy J, Ariza, Carlos A, Mael, Amber, Meyer, Kassondra, Shevde, Nirupama K, Roopra, Avtar, Lyons, Gary E, Kamp, Timothy J, Eliceiri, Kevin W, Ogle, Brenda M

“…The therapeutic potential of stem cells is limited by the non-uniformity of their phenotypic state. Thus it would be advantageous to noninvasively monitor stem…”
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Cell death, non-invasively assessed by intrinsic fluorescence intensity of NADH, is a predictive indicator of functional differentiation of embryonic stem cells by Buschke, David G., Squirrell, Jayne M., Fong, Jimmy J., Eliceiri, Kevin W., Ogle, Brenda M.

“…Background information Continued advances in stem cell biology and stem cell transplantation rely on non‐invasive biomarkers to characterise cells and stem…”
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Both Cyclin B levels and DNA-replication checkpoint control the early embryonic mitoses in Drosophila by Ji, Jun-Yuan, Squirrell, Jayne M, Schubiger, Gerold

“…The earliest embryonic mitoses in Drosophila , as in other animals except mammals, are viewed as synchronous and of equal duration. However, we observed that…”
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Altering Intracellular pH Disrupts Development and Cellular Organization in Preimplantation Hamster Embryos by SQUIRRELL, Jayne M, LANE, Michelle, BAVISTER, Barry D

“…In early cleavage stage hamster embryos, the inability to regulate intracellular pH (pH i ) properly is associated with reduced developmental competence in…”
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Citrullination regulates wound responses and tissue regeneration in zebrafish by Golenberg, Netta, Squirrell, Jayne M, Bennin, David A, Rindy, Julie, Pistono, Paige E, Eliceiri, Kevin W, Shelef, Miriam A, Kang, Junsu, Huttenlocher, Anna

“…Calcium is an important early signal in wound healing, yet how these early signals promote regeneration remains unclear. Peptidylarginine deiminases (PADs), a…”
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A novel bioreactor for combined magnetic resonance spectroscopy and optical imaging of metabolism in 3D cell cultures by Cox, Benjamin L., Erickson‐Bhatt, Sarah, Szulczewski, Joseph M., Squirrell, Jayne M., Ludwig, Kai D., Macdonald, Erin B., Swader, Robert, Ponik, Suzanne M., Eliceiri, Kevin W., Fain, Sean B.

“…Purpose Fluorescence lifetime imaging microscopy (FLIM) of endogenous fluorescent metabolites permits the measurement of cellular metabolism in cell, tissue…”
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zWEDGI: Wounding and Entrapment Device for Imaging Live Zebrafish Larvae by Huemer, Kayla, Squirrell, Jayne M, Swader, Robert, LeBert, Danny C, Huttenlocher, Anna, Eliceiri, Kevin W

“…Zebrafish, an established model organism in developmental biology, is also a valuable tool for imaging wound healing in space and time with cellular…”
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CGEF-1 and CHIN-1 regulate CDC-42 activity during asymmetric division in the Caenorhabditis elegans embryo by Kumfer, Kraig T, Cook, Steven J, Squirrell, Jayne M, Eliceiri, Kevin W, Peel, Nina, O'Connell, Kevin F, White, John G

“…The anterior-posterior axis of the Caenorhabditis elegans embryo is elaborated at the one-cell stage by the polarization of the partitioning (PAR) proteins at…”
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Multiphoton microscopy of endogenous fluorescence differentiates normal, precancerous, and cancerous squamous epithelial tissues by SKALA, Melissa C, SQUIRRELL, Jayne M, VROTSOS, Kristin M, EICKHOFF, Jens C, GENDRON-FITZPATRICK, Annette, ELICEIRI, Kevin W, RAMANUJAM, Nirmala

“…This study characterizes the morphologic features and the endogenous fluorescence in the stratified squamous epithelia of the…”
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Long-term Live Imaging Device for Improved Experimental Manipulation of Zebrafish Larvae by Huemer, Kayla, Squirrell, Jayne M, Swader, Robert, Pelkey, Kirsten, LeBert, Danny C, Huttenlocher, Anna, Eliceiri, Kevin W

“…The zebrafish larva is an important model organism for both developmental biology and wound healing. Further, the zebrafish larva is a valuable system for live…”
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Expression of the Drosophila homeobox gene, Distal‐less, supports an ancestral role in neural development by Plavicki, Jessica S., Squirrell, Jayne M., Eliceiri, Kevin W., Boekhoff‐Falk, Grace

“…Background: Distal‐less (Dll) encodes a homeodomain transcription factor expressed in developing appendages of organisms throughout metazoan phylogeny. Based…”
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Spatial and temporal analysis of extracellular matrix proteins in the developing murine heart: a blueprint for regeneration by Hanson, Kevin P, Jung, Jangwook P, Tran, Quyen A, Hsu, Shao-Pu P, Iida, Rioko, Ajeti, Visar, Campagnola, Paul J, Eliceiri, Kevin W, Squirrell, Jayne M, Lyons, Gary E, Ogle, Brenda M

“…The extracellular matrix (ECM) of the embryonic heart guides assembly and maturation of cardiac cell types and, thus, may serve as a useful template, or…”
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Relationship Between Development, Metabolism, and Mitochondrial Organization in 2-Cell Hamster Embryos in the Presence of Low Levels of Phosphate by LUDWIG, Tenneille E, SQUIRRELL, Jayne M, PALMENBERG, Ann C, BAVISTER, Barry D

“…The effect of low concentrations of inorganic phosphate (P i ) on development, metabolic activity, and mitochondrial organization in the same cohorts of…”
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