Search Results - "Squires, EJ"

The characterization of androstenone transport in boar plasma by Bone, Christine, Anderson, Courtney, Lou, Yanping, Squires, E.J.

“…•Androstenone circulates in the blood bound non-specifically to plasma proteins.•DHEA demonstrates a greater binding efficiency for plasma proteins than…”
Get full text

Cytoplasmic Localization of Pregnane X Receptor and Ligand-dependent Nuclear Translocation in Mouse Liver by Squires, E James, Sueyoshi, Tatsuya, Negishi, Masahiko

“…The pregnane X receptor (PXR) plays an important role in the response to xenobiotics and endogenous toxins. We have used a specific anti-PXR antibody in the…”
Get full text

Effects of feeding a blend of grains naturally contaminated with Fusarium mycotoxins on swine performance, brain regional neurochemistry, and serum chemistry and the efficacy of a polymeric glucomannan mycotoxin adsorbent by Swamy, H. V. L. N, Smith, T. K, MacDonald, E. J, Boermans, H. J, Squires, E. J

“…The co-occurrence of Fusarium mycotoxins in contaminated swine diets has been shown to result in synergistic toxicity beyond that observed for individual…”
Get full text

A comparative evaluation of thiobarbituric acid methods for the determination of malondialdehyde in biological materials by Draper, H H, Squires, E J, Mahmoodi, H, Wu, J, Agarwal, S, Hadley, M

“…A comparative evaluation was made of the conventional spectrophotometric procedure and three published high performance liquid chromatographic (HPLC)…”
Get more information

Testicular sulfoconjugation of the 16-androstene steroids by hydroxysteroid sulfotransferase : Its effect on the concentrations of 5α-androstenone in plasma and fat of the mature domestic boar by SINCLAIR, P. A, SQUIRES, E. J

“…This study examined the relationship between sulfoconjugation and the degree to which 5 alpha -androstenone can accumulate in fat. Analysis of the unconjugated…”
Get full text

Functional polymorphism in porcine CYP2E1 gene: Its association with skatole levels by Lin, Zhihong, Lou, Yanping, Squires, E. James

“…Raising intact male pigs would have a significant economic impact on the pork industry. However, the presence of skatole (a major cause of boar taint) in meat…”
Get full text

Metabolism of the 16-androstene steroids in primary cultured porcine hepatocytes by Sinclair, P.A., Hancock, S., Gilmore, W.J., Squires, E.J.

“…The hepatic metabolism of the 16-androstene steroids was investigated using isolated porcine hepatocytes. This study demonstrated that the liver is capable of…”
Get full text

Relationship between metabolism of androstenone and skatole in intact male pigs by Babol, J, Squires, E. J, Lundstrom, K

“…The relationship between the metabolism of androsterone and skatole, the major compounds responsible for boar taint, was investigated in F4 Swedish Yorkshire x…”
Get full text

Metabolism of 3-methylindole by porcine liver microsomes : Responsible cytochrome P450 enzymes by DIAZ, G. J, SQUIRES, E. J

“…The role of different cytochrome P450 enzymes on the metabolism of 3-methylindole (3MI) was investigated using selective chemical inhibitors. Eight chemical…”
Get full text

THE ROLE OF CYP2A AND CYP2E1 IN THE METABOLISM OF 3-METHYLINDOLE IN PRIMARY CULTURED PORCINE HEPATOCYTES by TERNER, Michael A, GILMORE, W. James, YANPING LOU, SQUIRES, E. James

“…The accumulation of 3-methylindole (3MI) in uncastrated male pigs (boars) is a major cause of boar taint, which negatively affects the quality of meat from the…”
Get full text

A novel polymorphism in the 5' untranslated region of the porcine cytochrome b5 (CYB5) gene is associated with decreased fat androstenone level by Lin, Zhihong, Lou, Yanping, Peacock, John, Squires, E James

“…Raising intact male pigs would have a significant economic impact on the pork industry; however, the presence of 16-androstene (a major cause of boar taint) in…”
Get full text

Age-related Variation of Plasma Concentrations of Skatole, Androstenone, Testosterone, Oestradiol-17β, Oestrone Sulphate, Dehydroepiandrosterone Sulphate, Triiodothyronine and IGF-1 in Six Entire Male Pigs by Zamaratskaia, G, Babol, J, Madej, A, Squires, EJ, Lundström, K

“…Contents This study describes the age‐related variation in boar taint compounds, skatole and androstenone, and testosterone, oestradiol‐17β (E17β), oestrone…”
Get full text

Synthesis of free and sulphoconjugated 16-androstene steroids by the Leydig cells of the mature domestic boar by Sinclair, P.A., Squires, E.J., Raeside, J.I., Renaud, R.

“…This study examined the involvement of sulphoconjugation in the biosynthesis of the 16-androstene steroids in Leydig cells of the mature boar, since the…”
Get full text

Molecular cloning and regulation of porcine SULT2A1: relationship between SULT2A1 expression and sulfoconjugation of androstenone by Sinclair, P A, Gilmore, W J, Lin, Z, Lou, Y, Squires, E J

“…Hydroxysteroid sulfotransferase (SULT2A1) is a key enzyme in the testicular and hepatic metabolism of 5α-androstenone, which is a major component of the…”
Get full text

Molecular cloning and functional analysis of porcine SULT1A1 gene and its variant: a single mutation SULT1A1 causes a significant decrease in sulfation activity by Lin, Zhihong, Lou, Yanping, Squires, James E

“…The characterization of the SULT1A1 gene and its variants should have an important impact on the efforts to develop genetic markers to select for low skatole…”
Get full text

Quality of meat from entire male pigs by Babol, Jakob, Squires, E.James

“…This paper reviews the meat quality characteristics of meat from entire male pigs. The advantages and disadvantages of meat from entire male pigs are…”
Get full text

Molecular cloning, expression and functional characterization of the cytochrome P450 2A6 gene in pig liver by Lin, Z, Lou, Y, Squires, E.J

“…Summary Raising intact male pigs would have a significant economic impact on the pork industry because intact males have improved feed efficiency and a greater…”
Get full text

Are the benefits of errorless learning dependent on implicit memory? by Hunkin, Nicola M., Squires, Ella J., Parkin, Alan J., Tidy, Julie A.

“…The effectiveness of errorless and errorful learning methods was compared in two experiments in which a group of memory-impaired individuals learned lists of…”
Get full text

Relationship between cytochrome P450IIE1 in liver and levels of skatole and its metabolites in intact male pigs by Squires, E.J, Lundstrom, K

“…The relationships between levels of skatole and androsterone in fat, plasma levels of skatole metabolites, plasma testosterone and estrone sulfate, and levels…”
Get full text

Errorless learning of novel associations in amnesia by Squires, Ella J., Hunkin, Nicola M., Parkin, Alan J.

“…In two experiments involving verbal association learning by people with memory impairments, the effectiveness of errorless learning (EL) was compared with…”
Get full text