Search Results - "Squire, Jeremy Andrew"

The Role of Somatic Mutations on the Immune Response of the Tumor Microenvironment in Prostate Cancer by Melo, Camila Morais, Vidotto, Thiago, Chaves, Luiz Paulo, Lautert-Dutra, William, Reis, Rodolfo Borges dos, Squire, Jeremy Andrew

“…Immunotherapy has improved patient survival in many types of cancer, but for prostate cancer, initial results with immunotherapy have been disappointing…”
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Contributions of HOX genes to cancer hallmarks: Enrichment pathway analysis and review by Brotto, Danielle Barbosa, Siena, Ádamo Davi Diógenes, de Barros, Isabela Ichihara, Carvalho, Simone da Costa e Silva, Muys, Bruna Rodrigues, Goedert, Lucas, Cardoso, Cibele, Plaça, Jessica Rodrigues, Ramão, Anelisa, Squire, Jeremy Andrew, Araujo, Luiza Ferreira, Silva, Wilson Araújo da

“…Homeobox genes function as master regulatory transcription factors during development, and their expression is often altered in cancer. The HOX gene family was…”
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Identification of a rare copy number polymorphic gain at 3q12.2 with candidate genes for familial endometriosis by Oliveira, Flávia Gaona, Rosa-E-Silva, Júlio Cesar, Gomes, Alexandra Galvão, Grzesiuk, Juliana Dourado, Vidotto, Thiago, Squire, Jeremy Andrew, Panepucci, Rodrigo Alexandre, Meola, Juliana, Martelli, Lúcia

“…Endometriosis is a complex disease that affects 10-15% of women of reproductive age. Familial studies show that relatives of affected patients have a higher…”
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Telomere Attrition in Isolated High-Grade Prostatic Intraepithelial Neoplasia and Surrounding Stroma Is Predictive of Prostate Cancer by Joshua, Anthony Michael, Vukovic, Bisera, Braudey, Ilan, Hussein, Sundus, Zielenska, Maria, Srigleyb, John, Evans, Andrew, Squire, Jeremy Andrew

“…The causes of early genomic events underlying the development of prostate cancer (CaP) remain unclear. The onset of chromosomal instability is likely to…”
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Abstract B30: PTEN loss associates with type I and II IFN response in prostate cancer by Vidotto, Thiago, Squire, Jeremy Andrew, Koti, Madhuri

“…Abstract PTEN gene deletion and protein loss occurs in 20-30% of prostate cancer (PCa) cases and leads to poor disease outcome. Loss of the PTEN tumor…”
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Abstract B58: The effect of differential miRNA expression in glioblastoma multiforme molecular subtypes by Verzola, Livia Ferreira Silva, Vidotto, Thiago, Squire, Jeremy Andrew

“…Abstract Glioblastoma multiforme (GBM) is characterized by a distinct profile of specific miRNAs that regulate pathways of therapeutic importance, such as cell…”
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Epithelial-Mesenchymal Transition Signaling and Prostate Cancer Stem Cells: Emerging Biomarkers and Opportunities for Precision Therapeutics by Chaves, Luiz Paulo, Melo, Camila Morais, Saggioro, Fabiano Pinto, Reis, Rodolfo Borges Dos, Squire, Jeremy Andrew

“…Prostate cancers may reactivate a latent embryonic program called the epithelial-mesenchymal transition (EMT) during the development of metastatic disease…”
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Abstract 6099: Differential gene expression related to TMPRSS2-ERG fusion, CDK12, RB1, TP53, AR and ZEB1 based on transcriptomic analysis of the TCGA PRAD cohort by Lautert-Dutra, William, Melo, Camila Morais, Chaves, Luiz Paulo, Caliari, André Luiz, Silva, Francisco Cesar Souza, Squire, Jeremy Andrew

“…Abstract Prostate Cancer (PCa) is considered an immunologically excluded tumor, unable to generate an effective T-cell response against cancer cells…”
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Abstract 6098: Analysis of the impact of ZEB1 expression on pathway enrichment and immune cell abundance in prostate cancer by Chaves, Luiz Paulo, Caliari, André Luiz, Lautert-Dutra, William, Silva, Francisco Cesar Souza, Melo, Camila Morais, Saggioro, Fabiano Pinto, Borges dos Reis, Rodolfo, Squire, Jeremy Andrew

“…Abstract Prostate cancer (PCa) reactivates a latent embryonic program called epithelial-mesenchymal transition during disease progression. The mesenchymal…”
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PTEN loss affects the immune and inflammatory response in prostate cancer by Vidotto, Thiago, Squire, Jeremy Andrew, Madhuri Koti, D.V.M.

“…Loss of the PTEN tumor suppressor gene occurs in 20-30% of prostate cancer (PCa) cases and is associated with worse disease outcome. Recent evidence highlights…”
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Chromosomal imbalances detected in primary bone tumors by comparative genomic hybridization and interphase fluorescence in situ hybridization by Baruffi, Marcelo Razera, Engel, Edgard Edward, Squire, Jeremy Andrew, Tone, Luis Gonzaga, Rogatto, Silvia Regina

“…We applied a combination of comparative genomic hybridization (CGH) and fluorescence in situ hybridization (FISH), to characterize the genetic aberrations in…”
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Molecular characterization of short-term primary cultures and comparison with corresponding tumor tissue of Brazilian glioblastoma patients by Cruvinel-Carloni, Adriana, Silva-Oliveira, Renato, Torrieri, Raul, Bidinotto, Lucas Tadeu, Berardinelli, Gustavo Noriz, Oliveira-Silva, Viviane Aline, Clara, Carlos Afonso, de Almeida, Gisele Caravina, Martinho, Olga, Squire, Jeremy Andrew, Reis, Rui Manuel

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Abstract 317: 1q32.1 and 16q21 genomic alterations implicate KIF14/MDM4/PIK3C2ß and CDH11 as independent prognostic markers of relapse in localized Ewing Family of Tumors by Ayala, Fernanda R.R, da Cunha, Isabela Werneck, Yoshimoto, Maisa, Zielenska, Maria, Squire, Jeremy Andrew, Soares, Fernando Augusto

“…Abstract EWS-ETS genetic fusion appears to be the initiating mechanism behind Ewing Family of Tumors (EFT) pathogenesis; however, progression of the disease is…”
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Prognostic impact of adenomatous polyposis coli gene expression in osteosarcoma of the extremities by Guimarães, Andréa Paiva Gadelha, Rocha, Rafael Malagoli, da Cunha, Isabela Werneck, Guimarães, Gustavo Cardoso, Carvalho, André Lopes, de Camargo, Beatriz, Lopes, Ademar, Squire, Jeremy Andrew, Soares, Fernando Augusto

“…Abstract Purpose To evaluate the impact of adjuvant chemotherapy on the outcome of osteosarcoma of the extremities, and to identify prognostic factors using…”
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Telomere Attrition in Isolated High-Grade Prostatic Intraepithelial Neoplasia and Surrounding Stroma Is Predictive of Prostate Cancer1 by Joshua, Anthony Michael, Vukovic, Bisera, Braudey, Ilan, Hussein, Sundus, Zielenska, Maria, Srigley, John, Evans, Andrew, Squire, Jeremy Andrew

“…The causes of early genomic events underlying the development of prostate cancer (CaP) remain unclear. The onset of chromosomal instability is likely to…”
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