Search Results - "Squair, Daniel R"

A new dawn beyond lysine ubiquitination by Squair, Daniel R., Virdee, Satpal

“…The ubiquitin system has become synonymous with the modification of lysine residues. However, the substrate scope and diversity of the conjugation machinery…”
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UBE2A and UBE2B are recruited by an atypical E3 ligase module in UBR4 by Barnsby-Greer, Lucy, Mabbitt, Peter D., Dery, Marc-Andre, Squair, Daniel R., Wood, Nicola T., Lamoliatte, Frederic, Lange, Sven M., Virdee, Satpal

“…UBR4 is a 574 kDa E3 ligase (E3) of the N-degron pathway with roles in neurodevelopment, age-associated muscular atrophy and cancer. The catalytic module that…”
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An affinity-directed phosphatase, AdPhosphatase, system for targeted protein dephosphorylation by Simpson, Luke M, Fulcher, Luke J, Sathe, Gajanan, Brewer, Abigail, Zhao, Jin-Feng, Squair, Daniel R, Crooks, Jennifer, Wightman, Melanie, Wood, Nicola T, Gourlay, Robert, Varghese, Joby, Soares, Renata F, Sapkota, Gopal P

“…Reversible protein phosphorylation, catalyzed by protein kinases and phosphatases, is a fundamental process that controls protein function and intracellular…”
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Targeting a critical step in fungal hexosamine biosynthesis by Lockhart, Deborah E.A., Stanley, Mathew, Raimi, Olawale G., Robinson, David A., Boldovjakova, Dominika, Squair, Daniel R., Ferenbach, Andrew T., Fang, Wenxia, van Aalten, Daan M.F.

“…Aspergillus fumigatus is a human opportunistic fungal pathogen whose cell wall protects it from the extracellular environment including host defenses. Chitin,…”
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Salt-inducible kinases (SIKs) regulate TGFβ-mediated transcriptional and apoptotic responses by Hutchinson, Luke D., Darling, Nicola J., Nicolaou, Stephanos, Gori, Ilaria, Squair, Daniel R., Cohen, Philip, Hill, Caroline S., Sapkota, Gopal P.

“…The signalling pathways initiated by members of the transforming growth factor-β (TGFβ) family of cytokines control many metazoan cellular processes, including…”
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