Search Results - "Spyrou, Nikolaos"

Obesity and cancer risk: Emerging biological mechanisms and perspectives by Avgerinos, Konstantinos I., Spyrou, Nikolaos, Mantzoros, Christos S., Dalamaga, Maria

“…Continuously rising trends in obesity-related malignancies render this disease spectrum a public health priority. Worldwide, the burden of cancer attributable…”
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Dark Energy: The Shadowy Reflection of Dark Matter? by Kleidis, Kostas, Spyrou, Nikolaos

“…In this article, we review a series of recent theoretical results regarding a conventional approach to the dark energy (DE) concept. This approach is…”
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Studying leukemia stem cell properties and vulnerabilities with human iPSCs by Spyrou, Nikolaos, Papapetrou, Eirini P.

“…•Reprogramming of AML cells into iPSCs provides a new model of AML LSCs.•iLSCs can aid the study of the biological properties of LSCs and CSCs more…”
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Classic and Novel Adipocytokines at the Intersection of Obesity and Cancer: Diagnostic and Therapeutic Strategies by Spyrou, Nikolaos, Avgerinos, Konstantinos I., Mantzoros, Christos S., Dalamaga, Maria

“…Purpose of Review In this review, we investigate the role of classic and novel adipocytokines in cancer pathogenesis synopsizing the mechanisms underlying the…”
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Dark Energy as a Natural Property of Cosmic Polytropes—A Tutorial by Kleidis, Kostas, Spyrou, Nikolaos K.

“…A conventional approach to the dark energy (DE) concept is reviewed and discussed. According to it, there is absolutely no need for a novel DE component in the…”
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Patient-specific MDS-RS iPSCs define the mis-spliced transcript repertoire and chromatin landscape of SF3B1-mutant HSPCs by Asimomitis, Georgios, Deslauriers, André G., Kotini, Andriana G., Bernard, Elsa, Esposito, Davide, Olszewska, Malgorzata, Spyrou, Nikolaos, Arango Ossa, Juan, Mortera-Blanco, Teresa, Koche, Richard, Nannya, Yasuhito, Malcovati, Luca, Ogawa, Seishi, Cazzola, Mario, Aaronson, Stuart A., Hellström-Lindberg, Eva, Papaemmanuil, Elli, Papapetrou, Eirini P.

“…SF3B1K700E is the most frequent mutation in myelodysplastic syndrome (MDS), but the mechanisms by which it drives MDS pathogenesis remain unclear. We derived a…”
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Special issue on “Excess body weight and cancer: Novel biologic insights and challenges” by Dalamaga, Maria, Spyrou, Nikolaos

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Magnetohydrodynamic flows as Newtonian-type gravitational motions by Spyrou Nikolaos, Tsagas Christos

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The interplay of obesity, gut microbiome and diet in the immune check point inhibitors therapy era by Spyrou, Nikolaos, Vallianou, Natalia, Kadillari, Jona, Dalamaga, Maria

“…Immunotherapy has recently emerged as a promising treatment option for many patients, revolutionizing the established therapeutic approach against cancer…”
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Effects of creatine supplementation on cognitive function of healthy individuals: A systematic review of randomized controlled trials by Avgerinos, Konstantinos I., Spyrou, Nikolaos, Bougioukas, Konstantinos I., Kapogiannis, Dimitrios

“…Creatine is a supplement used by sportsmen to increase athletic performance by improving energy supply to muscle tissues. It is also an essential brain…”
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Perspectives and Challenges of COVID-19 with Obesity-Related Cancers by Dalamaga, Maria, Nasiri-Ansari, Narjes, Spyrou, Nikolaos

“…The emergence of COVID-19 has created an unprecedented threat worldwide, involving overwhelmed health-care systems in the majority of countries [...]…”
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Gender Differences in Obesity-Related Cancers by Argyrakopoulou, Georgia, Dalamaga, Maria, Spyrou, Nikolaos, Kokkinos, Alexander

“…Purpose of review In this review, we summarize the role of obesity in carcinogenesis, providing details on specific cancer sites. Special emphasis is given to…”
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Obesity and main urologic cancers: Current systematic evidence, novel biological mechanisms, perspectives and challenges by Papavasileiou, Georgios, Tsilingiris, Dimitrios, Spyrou, Nikolaos, Vallianou, Natalia G., Karampela, Irene, Magkos, Faidon, Dalamaga, Maria

“…Urologic cancers (UC) account for 13.1% of all new cancer cases and 7.9% of all cancer-related deaths. A growing body of evidence has indicated a potential…”
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Body fatness associations with cancer: evidence from recent epidemiological studies and future directions by Larsson, Susanna C., Spyrou, Nikolaos, Mantzoros, Christos S.

“…This narrative review highlights current evidence linking greater body fatness to risk of various cancers, with focus on evidence from recent large cohort…”
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Could the endocrine disruptor bisphenol-A be implicated in the pathogenesis of oral and oropharyngeal cancer? Metabolic considerations and future directions by Emfietzoglou, Rodopi, Spyrou, Nikolaos, Mantzoros, Christos S., Dalamaga, Maria

“…Bisphenol-A (BPA), a prototype endocrine disrupting molecule, has been associated with many disease entities such as diabetes mellitus, obesity, polycystic…”
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The Role of Adipokines in Breast Cancer: Current Evidence and Perspectives by Christodoulatos, Gerasimos Socrates, Spyrou, Nikolaos, Kadillari, Jona, Psallida, Sotiria, Dalamaga, Maria

“…Purpose The current review shows evidence for the role of adipokines in breast cancer (BC) pathogenesis summarizing the mechanisms underlying the association…”
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Management of venous thromboembolism in pregnancy by Kalaitzopoulos, Dimitrios Rafail, Panagopoulos, Anastasios, Samant, Saurabhi, Ghalib, Natasha, Kadillari, Jona, Daniilidis, Angelos, Samartzis, Nicolas, Makadia, Janaki, Palaiodimos, Leonidas, Kokkinidis, Damianos G., Spyrou, Nikolaos

“…Venous thromboembolism (VTE) in pregnancy, consisting of deep venous thrombosis (DVT) and pulmonary embolism (PE), is a major factor of maternal mortality…”
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Management of Hematologic Malignancies in the Era of COVID-19 Pandemic: Pathogenetic Mechanisms, Impact of Obesity, Perspectives, and Challenges by Tsilingiris, Dimitrios, Nasiri-Ansari, Narjes, Spyrou, Nikolaos, Magkos, Faidon, Dalamaga, Maria

“…The COVID-19 pandemic brought about an unprecedented societal and healthcare system crisis, considerably affecting healthcare workers and patients,…”
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Acute GVHD: New approaches to clinical trial monitoring by Spyrou, Nikolaos, Levine, John E., Ferrara, James L.M.

“…Acute GVHD occurs in nearly 50% of patients receiving hematopoietic cell transplantation (HCT), and is the major driver of mortality. However, progress in the…”
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Lorcaserin Administration Decreases Activation of Brain Centers in Response to Food Cues and These Emotion- and Salience-Related Changes Correlate With Weight Loss Effects: A 4-Week-Long Randomized, Placebo-Controlled, Double-Blind Clinical Trial by Farr, Olivia M, Upadhyay, Jagriti, Gavrieli, Anna, Camp, Michelle, Spyrou, Nikolaos, Kaye, Harper, Mathew, Hannah, Vamvini, Maria, Koniaris, Anastasia, Kilim, Holly, Srnka, Alexandra, Migdal, Alexandra, Mantzoros, Christos S

“…Lorcaserin is a serotonin 5-hydroxytryptamine 2c receptor agonist effective in treating obesity. Studies in rodents have shown that lorcaserin acts in the…”
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