Search Results - "Spyres, Lea M."

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  1. 1
    Mutational Analysis of the Enzymatic Domain of Clostridium difficile Toxin B Reveals Novel Inhibitors of the Wild-Type Toxin

    Mutational Analysis of the Enzymatic Domain of Clostridium difficile Toxin B Reveals Novel Inhibitors of the Wild-Type Toxin by Spyres, L M, Daniel, J, Hensley, A, Qa'Dan, M, Ortiz-Leduc, W, Ballard, J D

    Published in Infection and Immunity (01-06-2003)
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  2. 2
    Cytosolic Delivery and Characterization of the TcdB Glucosylating Domain by Using a Heterologous Protein Fusion

    Cytosolic Delivery and Characterization of the TcdB Glucosylating Domain by Using a Heterologous Protein Fusion by SPYRES, Lea. M, MAEN QA'DAN, MEADER, Amy, TOMASEK, James J, HOWARD, Eric W, BALLARD, Jimmy D

    Published in Infection and Immunity (01-01-2001)
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  3. 3
    Clostridium difficile toxin B activates dual caspase‐dependent and caspase‐independent apoptosis in intoxicated cells

    Clostridium difficile toxin B activates dual caspase‐dependent and caspase‐independent apoptosis in intoxicated cells by Qa’Dan, Maen, Ramsey, Matthew, Daniel, Jeremy, Spyres, Lea M., Safiejko‐Mroczka, Barbara, Ortiz‐Leduc, William, Ballard, Jimmy D.

    Published in Cellular microbiology (01-07-2002)
    “…Summary Clostridium difficile toxin B (TcdB) inactivates the small GTPases Rho, Rac and Cdc42 during intoxi‐cation of mammalian cells. In the current work, we…”
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  4. 4
    pH-Enhanced cytopathic effects of Clostridium sordellii lethal toxin

    pH-Enhanced cytopathic effects of Clostridium sordellii lethal toxin by QA'DAN, Maen, SPYRES, Lea M, BALLARD, Jimmy D

    Published in Infection and immunity (01-09-2001)
    “…Clostridium sordellii lethal toxin (TcsL) is a large clostridial toxin (LCT) that glucosylates Ras, Rac, and Ral. TcsL differs from other LCTs because it…”
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  5. 5
    ph-induced conformational changes in Clostridium difficile toxin B

    ph-induced conformational changes in Clostridium difficile toxin B by MEAN QA'DAN, SPYRES, L. M, BALLARD, J. D

    Published in Infection and immunity (01-05-2000)
    “…Toxin B from Clostridium difficile is a monoglucosylating toxin that targets substrates within the cytosol of mammalian cells. In this study, we investigated…”
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  6. 6
    pH-Enhanced Cytopathic Effects ofClostridium sordellii Lethal Toxin

    pH-Enhanced Cytopathic Effects ofClostridium sordellii Lethal Toxin by Maen Qa'Dan, Lea M. Spyres, Jimmy D. Ballard

    Published in Infection and Immunity (01-09-2001)
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  7. 7
    pH-Induced Conformational Changes inClostridium difficile Toxin B

    pH-Induced Conformational Changes inClostridium difficile Toxin B by Maen Qa'Dan, Lea M. Spyres, Jimmy D. Ballard

    Published in Infection and Immunity (01-05-2000)
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