Search Results - "Spurlock, Markus S."
-
1
Microglial Inflammasome Activation in Penetrating Ballistic-Like Brain Injury
Published in Journal of neurotrauma (15-07-2018)“…Penetrating traumatic brain injury (PTBI) is a significant cause of death and disability in the United States. Inflammasomes are one of the key regulators of…”
Get more information
Journal Article -
2
Evidence to support mitochondrial neuroprotection, in severe traumatic brain injury
Published in Journal of bioenergetics and biomembranes (01-04-2015)“…Traumatic brain injury (TBI) is still the leading cause of disability in young adults worldwide. The major mechanisms – diffuse axonal injury, cerebral…”
Get full text
Journal Article -
3
Amelioration of Penetrating Ballistic-Like Brain Injury Induced Cognitive Deficits after Neuronal Differentiation of Transplanted Human Neural Stem Cells
Published in Journal of neurotrauma (01-06-2017)“…Penetrating traumatic brain injury (PTBI) is one of the major cause of death and disability worldwide. Previous studies with penetrating ballistic-like brain…”
Get more information
Journal Article -
4
Microdialysis as Clinical Evaluation of Therapeutic Hypothermia in Rat Subdural Hematoma Model
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2016)“…Cerebral microdialysis (MD) is a fine laboratory technique which has been established for studying physiological, pharmacological, and pathological changes in…”
Get more information
Journal Article -
5
Injury-Transplantation Interval-Dependent Amelioration of Axonal Degeneration and Motor Deficit in Rats with Penetrating Traumatic Brain Injury
Published in Neurotrauma reports (01-04-2023)“…Penetrating traumatic brain injury (pTBI) is increasingly survivable, but permanently disabling as adult mammalian nervous system does not regenerate…”
Get full text
Journal Article -
6
Feasibility of Human Neural Stem Cell Transplantation for the Treatment of Acute Subdural Hematoma in a Rat Model: A Pilot Study
Published in Frontiers in neurology (12-02-2019)“…Human neural stem cells (hNSCs) transplantation in several brain injury models has established their therapeutic potential. However, the feasibility of hNSCs…”
Get full text
Journal Article -
7
Enduring Neuroprotective Effect of Subacute Neural Stem Cell Transplantation After Penetrating TBI
Published in Frontiers in neurology (17-01-2019)“…Traumatic brain injury (TBI) is the largest cause of death and disability of persons under 45 years old, worldwide. Independent of the distribution, outcomes…”
Get full text
Journal Article -
8
Subdural hematoma decompression model: A model of traumatic brain injury with ischemic-reperfusional pathophysiology: A review of the literature
Published in Behavioural brain research (15-03-2018)“…•The prognosis for traumatic brain injury (TBI) patients with subdural hematoma (SDH) remains poor.•Removal of the SDH results in the immediate reversal of…”
Get full text
Journal Article -
9
Human neural stem cell transplant location–dependent neuroprotection and motor deficit amelioration in rats with penetrating traumatic brain injury
Published in The journal of trauma and acute care surgery (01-04-2020)“…Penetrating traumatic brain injury induces chronic inflammation that drives persistent tissue loss long after injury. Absence of endogenous reparative…”
Get full text
Journal Article