Search Results - "Spudich, Annett"
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Inhibition of multidrug resistance transporter-1 facilitates neuroprotective therapies after focal cerebral ischemia
Published in Nature neuroscience (01-04-2006)“…The blood-brain barrier possesses active transporters carrying brain-permeable xenobiotics back into the blood against concentration gradients. We demonstrate…”
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Aggravation of ischemic brain injury by prion protein deficiency: Role of ERK-1/-2 and STAT-1
Published in Neurobiology of disease (01-11-2005)“…The cellular isoform of prion protein, PrP c, may confer neuroprotection in the brain, according to recent studies. To elucidate the role of PrP c in stroke…”
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ABCC1: a gateway for pharmacological compounds to the ischaemic brain
Published in Brain (London, England : 1878) (01-10-2008)“…By preventing access of drugs to the CNS, the blood–brain barrier hampers developments in brain pharmacotherapy. Strong efforts are currently being made to…”
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Human Vascular Endothelial Growth Factor Protects Axotomized Retinal Ganglion Cells In Vivo by Activating ERK-1/2 and Akt Pathways
Published in The Journal of neuroscience (29-11-2006)“…Based on its trophic effects on neurons and vascular cells, vascular endothelial growth factor (VEGF) is a promising candidate for the treatment of…”
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Role of drug efflux carriers in the healthy and diseased brain
Published in Annals of neurology (01-11-2006)“…The blood–brain barrier is a natural diffusion barrier, which expresses active carriers extruding drugs on their way to the brain back into the blood against…”
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ABCCI : a gateway for pharmacological compounds to the ischaemic brain
Published in Brain (London, England : 1878) (2008)Get full text
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