Search Results - "Spudich, Annett"

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  1. 1

    Inhibition of multidrug resistance transporter-1 facilitates neuroprotective therapies after focal cerebral ischemia by Hermann, Dirk M, Spudich, Annett, Kilic, Ertugrul, Xing, Hongyi, Kilic, Ülkan, Rentsch, Katharina M, Wunderli-Allenspach, Heidi, Bassetti, Claudio L

    Published in Nature neuroscience (01-04-2006)
    “…The blood-brain barrier possesses active transporters carrying brain-permeable xenobiotics back into the blood against concentration gradients. We demonstrate…”
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    Journal Article
  2. 2

    Aggravation of ischemic brain injury by prion protein deficiency: Role of ERK-1/-2 and STAT-1 by Spudich, Annett, Frigg, Rico, Kilic, Ertugrul, Kilic, Ülkan, Oesch, Bruno, Raeber, Alex, Bassetti, Claudio L., Hermann, Dirk M.

    Published in Neurobiology of disease (01-11-2005)
    “…The cellular isoform of prion protein, PrP c, may confer neuroprotection in the brain, according to recent studies. To elucidate the role of PrP c in stroke…”
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    Journal Article
  3. 3

    ABCC1: a gateway for pharmacological compounds to the ischaemic brain by Kilic, Ertugrul, Spudich, Annett, Kilic, Ülkan, Rentsch, Katharina M., Vig, Raluca, Matter, Christian M., Wunderli-Allenspach, Heidi, Fritschy, Jean-Marc, Bassetti, Claudio L., Hermann, Dirk M.

    Published in Brain (London, England : 1878) (01-10-2008)
    “…By preventing access of drugs to the CNS, the blood–brain barrier hampers developments in brain pharmacotherapy. Strong efforts are currently being made to…”
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    Journal Article
  4. 4

    Human Vascular Endothelial Growth Factor Protects Axotomized Retinal Ganglion Cells In Vivo by Activating ERK-1/2 and Akt Pathways by Kilic, Ulkan, Kilic, Ertugrul, Jarve, Anne, Guo, Zeyun, Spudich, Annett, Bieber, Katja, Barzena, Uxue, Bassetti, Claudio L, Marti, Hugo H, Hermann, Dirk M

    Published in The Journal of neuroscience (29-11-2006)
    “…Based on its trophic effects on neurons and vascular cells, vascular endothelial growth factor (VEGF) is a promising candidate for the treatment of…”
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    Journal Article
  5. 5

    Role of drug efflux carriers in the healthy and diseased brain by Hermann, Dirk M., Kilic, Ertugrul, Spudich, Annett, Krämer, Stefanie D., Wunderli-Allenspach, Heidi, Bassetti, Claudio L.

    Published in Annals of neurology (01-11-2006)
    “…The blood–brain barrier is a natural diffusion barrier, which expresses active carriers extruding drugs on their way to the brain back into the blood against…”
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    Journal Article
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