Search Results - "Sprouse, Alyssa A"
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Pharmaceutical regulation of telomerase and its clinical potential
Published in Journal of cellular and molecular medicine (01-01-2012)“…• Introduction • Telomerase inhibitors • Telomerase activators • Conclusions and perspectives Telomeres serve the dual function of protecting chromosomes…”
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Journal Article -
2
Pharmacokinetic Interactions between Drugs and Botanical Dietary Supplements
Published in Drug metabolism and disposition (01-02-2016)“…The use of botanical dietary supplements has grown steadily over the last 20 years despite incomplete information regarding active constituents, mechanisms of…”
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Journal Article -
3
Resveratrol augments paclitaxel treatment in MDA-MB-231 and paclitaxel-resistant MDA-MB-231 breast cancer cells
Published in Anticancer research (01-10-2014)“…Resveratrol (RES) inhibits cell growth, induces apoptosis and augments chemotherapeutics in multiple cancer types, although its effects on drug-resistant…”
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Journal Article -
4
Potentiation of Carboplatin-Mediated DNA Damage by the Mdm2 Modulator Nutlin-3a in a Humanized Orthotopic Breast-to-Lung Metastatic Model
Published in Molecular cancer therapeutics (01-12-2015)“…Triple-negative breast cancers (TNBC) are typically resistant to treatment, and strategies that build upon frontline therapy are needed. Targeting the murine…”
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Journal Article -
5
Medical genetics and epigenetics of telomerase
Published in Journal of cellular and molecular medicine (01-03-2011)“…• Introduction • Epigenetic regulation of telomerase: recent findings beyond transcriptional control ‐ Methylation ‐ Sirtuins ‐ Non‐coding RNAs • …”
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Journal Article -
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Abstract 876: Molecular mechanisms of paclitaxel-resistance and resveratrol sensitivity in MDA-MB-231 breast cancer cells
Published in Cancer research (Chicago, Ill.) (15-04-2013)“…Treatment of drug-resistant cancer cells remains a difficult problem in cancer therapy because most resistant cells can pump out drugs or upregulate other…”
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Journal Article -
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Abstract 5676: Effects of resveratrol on paclitaxel-sensitive and -resistant triple negative breast cancer cells
Published in Cancer research (Chicago, Ill.) (15-04-2012)“…Treatment of drug-resistant cancer cells remains a difficult problem in cancer therapy because most resistant cells can pump out drugs or upregulate other…”
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Journal Article -
8
Resveratrol augments paclitaxel treatment in MDA-MB-231 and paclitaxel-resistant MDA-MB-231 breast cancer cells
Published 01-01-2014“…Resveratrol has been shown to inhibit cell growth and induce apoptosis, as well as augment chemotherapeutics and irradiation in multiple cancer types. However,…”
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Dissertation -
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Resveratrol augments paclitaxel treatment in MDA-MB-231 and paclitaxel-resistant MDA-MB-231 breast cancer cells
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Dissertation