Search Results - "Spritzler, J"

Serum Neopterin, an Immune Activation Marker, Independently Predicts Disease Progression in Advanced HIV-1 Infection by Mildvan, Donna, Spritzler, John, Grossberg, Sidney E., Fahey, John L., Johnston, David M., Schock, Barbara R., Kagan, Jonathan

“…Background. CD4+ T lymphocyte (CD4) counts and plasma human immunodeficiency virus (HIV) type 1 RNA concentrations predict clinical outcome in HIV-1 infection…”
Get full text

Immunologic Responses Associated with 12 Weeks of Combination Antiretroviral Therapy Consisting of Zidovudine, Lamivudine, and Ritonavir: Results of AIDS Clinical Trials Group Protocol 315 by Lederman, Michael M., Connick, Elizabeth, Landay, Alan, Kuritzkes, Daniel R., Spritzler, John, St. Clair, Marty, Kotzin, Brian L., Fox, Lawrence, Heath Chiozzi, Margo, Leonard, John M., Rousseau, Franck, Wade, Michael, Roe, Joana D'Arc, Martinez, Ana, Kessler, Harold

“…Human immunodeficiency virus (HIV)-1 infection is associated with progressive cell-mediated immune deficiency and abnormal immune activation. Although highly…”
Get full text

Thalidomide for the Treatment of Oral Aphthous Ulcers in Patients with Human Immunodeficiency Virus Infection by Jacobson, Jeffrey M, Greenspan, John S, Spritzler, John, Ketter, Nzeera, Fahey, John L, Jackson, J. Brooks, Fox, Lawrence, Chernoff, Miriam, Wu, Albert W, MacPhail, Laurie A, Vasquez, Guillermo J, Wohl, David A

“…Aphthous ulceration of the mouth, though painful and annoying, is usually a self-limited problem in immunocompetent persons. 1 In patients with human…”
Get full text

Thymic Size and Lymphocyte Restoration in Patients with Human Immunodeficiency Virus Infection after 48 Weeks of Zidovudine, Lamivudine, and Ritonavir Therapy by Smith, Kimberly Y., Valdez, H., Landay, A., Spritzler, J., Kessler, H. A., Connick, E., Kuritzkes, D., Gross, B., Francis, I., McCune, J. M., Lederman, M. M.

“…Human immunodeficiency virus (HIV) infection is associated with progressive loss of circulating CD4+ lymphocytes. Treatment with highly active antiretroviral…”
Get full text

Pharmacokinetics, Safety, and Antiviral Effects of Hypericin, a Derivative of St. John's Wort Plant, in Patients with Chronic Hepatitis C Virus Infection by JACOBSON, Jeffrey M, FEINMAN, Lawrence, LIEBES, Leonard, OSTROW, Nancy, KOSLOWSKI, Victoria, TOBIA, Alfonso, CABANA, Bernard E, LEE, Dong-Hun, SPRITZLER, John, PRINCE, Alfred M

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

In Vitro Cell-Mediated Immune Responses of Human Immunodeficiency Virus-Infected and -Uninfected Individuals to Whole Cytomegalovirus Antigens and Their Subunits by Weinberg, A, Spritzler, J, Nokta, M, Schrier, R, Landay, A, Brown, D, Pollard, R

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Thalidomide for the Treatment of Esophageal Aphthous Ulcers in Patients with Human Immunodeficiency Virus Infection by Jacobson, Jeffrey M., Spritzler, John, Fox, Lawrence, Fahey, John L., Jackson, J. Brooks, Chernoff, Miriam, Wohl, David A., Wu, Albert W., Hooton, Thomas M., Sha, Beverly E., Shikuma, Cecilia M., MacPhail, Laurie A., Simpson, David M., Trapnell, Carol B., Basgoz, Nesli

“…A multicenter, double-blind, randomized, placebo-controlled clinical trial was conducted to determine the safety and efficacy of thalidomide for treating…”
Get full text

Pharmacokinetics and Pharmacodynamics of Thalidomide in HIV Patients Treated for Oral Aphthous Ulcers: ACTG Protocol 251 by Aweeka, Francesca, Trapnell, Carol, Chernoff, Miriam, Jayewardene, Anura, Spritzler, John, Bellibas, S. Eralp, Lizak, Patricia, Jacobson, Jeffrey

“…Thalidomide has increasing clinical benefits, including the healing of aphthous ulcers in patients with HIV. Unfortunately, pharmacological information…”
Get full text

High-Dose Pentoxifylline in Patients with AIDS: Inhibition of Tumor Necrosis Factor Production by Dezube, Bruce J., Lederman, Michael M., Spritzler, John G., Chapman, Beryl, Korvick, Joyce A., Flexner, Charles, Dando, Stephen, Mattiacci, Maria R., Ahlers, Christoph M., Zhang, Lin, Novick, William J., Kasdan, Patricia, Fahey, John L., Pardee, Arthur B., Crumpacker, Clyde S.

“…Tumor necrosis factor-α (TNF) may activate human immunodeficiency virus (HIV), antagonize zidovudine activity, and contribute to AIDS wasting syndrome…”
Get full text

Incomplete Reconstitution of T Cell Subsets on Combination Antiretroviral Therapy in the AIDS Clinical Trials Group Protocol 384 by Robbins, Gregory K., Spritzler, John G., Chan, Ellen S., Asmuth, David M., Gandhi, Rajesh T., Rodriguez, Benigno A., Skowron, Gail, Skolnik, Paul R., Shafer, Robert W., Pollard, Richard B.

“…Background. Initiation of combination antiretroviral therapy (ART) results in higher total CD4 cell counts, a surrogate for immune reconstitution. Whether the…”
Get full text

Human immunodeficiency virus type 1 activation after blood transfusion by Mudido, P M, Georges, D, Dorazio, D, Yen-Lieberman, B, Bae, S, O'Brien, W A, Spritzler, J, Lederman, M M

“…Anemia and transfusion are predictors of disease progression in AIDS patients. This study was designed to examine the effects of blood transfusion on human…”
Get more information

Delayed-Type Hypersensitivity to Recombinant HIV Envelope Glycoprotein (rgp160) After Immunization With Homologous Antigen by Katzenstein, D A, Kundu, S, Spritzler, J, Smoller, B R, Haszlett, P, Valentine, F, Merigan, T C

“…Delayed-type hypersensitivity (DTH) responses to intradermal recombinant HIV envelope glycoprotein (rgp160) may assess cell-mediated immune responses to HIV…”
Get full text

Response to immunization with recall and neoantigens after prolonged administration of an HIV-1 protease inhibitor-containing regimen. ACTG 375 team. AIDS Clinical Trials Group by Valdez, H, Smith, K Y, Landay, A, Connick, E, Kuritzkes, D R, Kessler, H, Fox, L, Spritzler, J, Roe, J, Lederman, M B, Lederman, H M, Evans, T G, Heath-Chiozzi, M, Lederman, M M

“…To ascertain if immunization results in the restoration of responses to recall antigens, in the development of responses to presumed neoantigens, and to…”
Get full text

Effect of Baseline- and Treatment-Related Factors on Immunologic Recovery After Initiation of Antiretroviral Therapy in HIV-1-Positive Subjects: Results From ACTG 384 by Gandhi, Rajesh T, Spritzler, John, Chan, Ellen, Asmuth, David M, Rodriguez, Benigno, Merigan, Thomas C, Hirsch, Martin S, Shafer, Robert W, Robbins, Gregory K, Pollard, Richard B

“…OBJECTIVE:To assess the effect of baseline- and treatment-related factors on immunologic recovery after initiation of antiretroviral therapy (ART)…”
Get full text

Alteration of complement protein levels after antiretroviral therapy in HIV-infected persons by Spear, G T, Olinger, G, Sullivan, B L, Landay, A L, Kessler, H, Connick, E, Kuritzkes, D, St Clair, M, Spritzler, J, Wu, H, Lederman, M M

Get more information

Thalidomide for Aphthous Ulcers in HIV Infection by Birnkrant, D

“…To the Editor: Jacobson et al. (May 22 issue) 1 report encouraging results in their placebo-controlled trial of thalidomide for aphthous ulceration in patients…”
Get full text

Reanalysis of Coreceptor Tropism in HIV-1—Infected Adults Using a Phenotypic Assay with Enhanced Sensitivity by Wilkin, Timothy J., Goetz, Mathew Bidwell, Leduc, Robert, Skowron, Gail, Su, Zhaohui, Chan, Ellen S., Heera, Jayyant, Chapman, Doug, Spritzler, John, Reeves, Jacqueline D., Gulick, Roy M., Coakley, Eoin

“…The enhanced-sensitivity Trofile assay (TF-ES; Monogram Biosciences) was used to retest coreceptor tropism samples from 4 different cohorts of HIV-1-infected…”
Get full text

A potential role for interleukin-7 in T-cell homeostasis by Fry, Terry J., Connick, Elizabeth, Falloon, Judith, Lederman, Michael M., Liewehr, David J., Spritzler, John, Steinberg, Seth M., Wood, Lauren V., Yarchoan, Robert, Zuckerman, Judy, Landay, Alan, Mackall, Crystal L.

“…Interleukin (IL)-7 is known to up-regulate thymopoietic pathways of T-cell regeneration. Recent work also has shown it to potently enhance thymic-independent…”
Get full text

Age-Related Immune Dysfunction in Health and in Human Immunodeficiency Virus (HIV) Disease: Association of Age and HIV Infection with Naive CD8+ Cell Depletion, Reduced Expression of CD28 on CD8+ Cells, and Reduced Thymic Volumes by Kalayjian, Robert C, Landay, Alan, Pollard, Richard B, Taub, Dennis D, Gross, Barry H, Francis, Isaac R, Sevin, Anne, Pu, Minya, Spritzler, John, Chernoff, Miriam, Namkung, Ann, Fox, Lawrence, Martinez, Ana, Waterman, Karen, Fiscus, Susan A, Sha, Beverly, Johnson, Debra, Slater, Stanley, Rousseau, Frank

“…Older age is a strong predictor of accelerated human immunodeficiency virus (HIV) disease progression. We investigated the possible immunologic basis of this…”
Get full text

Maximum suppression of HIV replication leads to the restoration of HIV-specific responses in early HIV disease by Al-Harthi, L, Siegel, J, Spritzler, J, Pottage, J, Agnoli, M, Landay, A

“…It is predicted that HIV-infected individuals in early HIV disease are the most likely group to achieve immune reconstitution following highly active…”
Get full text