Search Results - "Sprinkle, T J"
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A pathology-MRI study of the short-T2 component in formalin-fixed multiple sclerosis brain
Published in Neurology (28-11-2000)“…To determine the pathologic basis of areas not exhibiting signal of the short-T2 component of the T2 relaxation distribution in MS, as studied in…”
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Multiple sclerosis. Oligodendrocyte proliferation and differentiation in fresh lesions
Published in Laboratory investigation (01-11-1989)“…Fresh lesions in the brain and spinal cord of patients with multiple sclerosis who died shortly after the onset of symptoms were examined immunocytochemically…”
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Cloning, Chromosomal Sublocalization of the Human Soluble Aminopeptidase P Gene (XPNPEP1) to 10q25.3 and Conservation of the Putative Proton Shuttle and Metal Ligand Binding Sites with XPNPEP2
Published in Archives of biochemistry and biophysics (01-06-2000)“…Human soluble (“cytosolic”) aminopeptidase P (hsAmP) is an aminoacylprolyl hydrolase (EC 3.4.11.9) present in all tissues yet examined. hsAmP is related in…”
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Assignment of the Membrane-Bound Human Aminopeptidase P Gene (XPNPEP2) to Chromosome Xq25
Published in Genomics (San Diego, Calif.) (15-05-1998)Get full text
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Oligodendrocyte reactions and cell proliferation markers in human demyelinating diseases
Published in Neuropathology and applied neurobiology (01-06-1994)“…We have carried out immunocytochemical reactions using antibodies to markers of oligodendrocytes, astrocytes, microglia and proliferating cells (PCNA) in…”
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Mitochondrial schwannopathy and peripheral myelinopathy in a rabbit model of dideoxycytidine neurotoxicity
Published in Laboratory investigation (01-05-1994)“…The reverse transcriptase inhibitor, 2',3'-dideoxycytidine (ddC), causes a dose-limiting peripheral neuropathy in humans, the mechanism of which is unknown…”
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2',3'-cyclic nucleotide 3'-phosphodiesterase, an oligodendrocyte-Schwann cell and myelin-associated enzyme of the nervous system
Published in Critical reviews in neurobiology (1989)“…2',3'-Cyclic nucleotide 3'-phosphohydrolase (E.C. 3.1.4.37; CNPase) is a myelin-associated enzyme. In central and peripheral nervous system tissues, the enzyme…”
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Oligodendrocyte Substratum Adhesion Modulates Expression of Adenylate Cyclase-Linked Receptors
Published in Proceedings of the National Academy of Sciences - PNAS (01-02-1988)“…The molecular mechanisms of myelin formation/reformation in the central nervous system are unknown. In previous work we have demonstrated that mature…”
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Differential expression of galactocerebroside, myelin basic protein, and 2',3'-cyclic nucleotide 3'-phosphohydrolase during development of oligodendrocytes in vitro
Published in Journal of neuroscience research (01-10-1988)“…This paper describes the differential expression and localization of myelin components within membrane sheets produced by oligodendrocytes in vitro. In…”
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2',3'-cyclic nucleotide-3'-phosphodiesterase in the central nervous system is fatty-acylated by thioester linkage
Published in The Journal of biological chemistry (15-07-1990)“…2',3'-Cyclic nucleotide-3'-phosphodiesterase (CNP1 and CNP2 with Mr of 46,000 and 48,000, respectively) is the major enzyme of central nervous system myelin…”
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Assignment of the human 2',3'-cyclic nucleotide 3'-phosphohydrolase gene to chromosome 17
Published in Genomics (San Diego, Calif.) (01-07-1992)“…2',3'-Cyclic nucleotide 3'-phosphohydrolase (CNP) has been used as a general oligodendrocyte and Schwann cell marker enzyme within the nervous system and has…”
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Chromosomal mapping of the human CNP gene using a meiotic crossover DNA panel, PCR, and allele-specific probes
Published in Genomics (San Diego, Calif.) (01-05-1993)“…The human 2',3'-cyclic nucleotide 3'-phosphohydrolase (CNP) gene is located on chromosome 17, as determined by PCR of somatic cell hybrid DNA panels and…”
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Monoclonal antibody production to human and bovine 2':3'-cyclic nucleotide 3'-phosphodiesterase (CNPase): high-specificity recognition in whole brain acetone powders and conservation of sequence between CNP1 and CNP2
Published in Brain research (24-11-1987)“…Monoclonal antibodies against human and bovine 2':3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) were generated by fusing FOX-NY myeloma cells with spleen…”
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Immunochemical identification of 2', 3'-cyclic nucleotide 3'-phosphodiesterase in central and peripheral nervous system myelin, the Wolfgram protein fraction, and bovine oligodendrocytes
Published in Journal of neurochemistry (01-01-1983)“…Myelin proteins and the total Wolfgram protein fraction were isolated from the CNS of several mammalian species and characterized with rabbit anti-bovine 2',…”
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Intracellular localization of 2',3'-cyclic nucleotide 3'-phosphohydrolase in rat oligodendrocytes and C6 glioma cells, and effect of cell maturation and enzyme induction on localization
Published in Brain research (30-01-1984)“…We investigated whether the membrane-associated myelin enzyme, 2',3'-cyclic nucleotide 3'-phosphohydrolase (CNP; EC 3.1.4.37), is localized primarily inside…”
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An immunochemical investigation of 2':3'-cyclic nucleotide 3'-phosphodiesterase (CNP) in bovine cerebrum and human oligodendroglioma
Published in Journal of neuroscience research (1985)“…Bovine cerebrum, including the corpus callosum, and a human oligodendroglioma were investigated by an immunohistochemical technique to determine the…”
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An investigation of 2':3'-cyclic nucleotide 3'-phosphodiesterase (EC 3.1.4.37, CNP) in peripheral blood elements and CNS myelin
Published in Life sciences (1973) (30-04-1984)“…Activity of 2':3'-cyclic nucleotide 3'-phosphodiesterase (CNP) of human erythrocyte membranes was determined in the presence of various brain CNP inhibitory…”
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Immunofluorescence demonstration of 2':3'-cyclic-nucleotide 3'-phosphodiesterase in cultured oligodendrocytes of mouse, rat, calf and human
Published in Brain research (21-05-1984)“…Previous biochemical studies have shown that high enzyme activity of 2':3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) is found in isolated myelin and…”
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