Search Results - "Springhorn, J P"

A novel mechanism of retrovirus inactivation in human serum mediated by anti-alpha-galactosyl natural antibody by Rother, R P, Fodor, W L, Springhorn, J P, Birks, C W, Setter, E, Sandrin, M S, Squinto, S P, Rollins, S A

“…Type C retroviruses endogenous to various nonprimate species can infect human cells in vitro, yet the transmission of these viruses to humans is restricted…”
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Adult rat ventricular myocytes cultured in defined medium: phenotype and electromechanical function by Ellingsen, O, Davidoff, A J, Prasad, S K, Berger, H J, Springhorn, J P, Marsh, J D, Kelly, R A, Smith, T W

“…We studied primary short-term cultures of adult rat ventricular myocytes in defined medium to determine whether phenotype and electromechanical function are…”
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Translation of heart preproenkephalin mRNA and secretion of enkephalin peptides from cultured cardiac myocytes by Springhorn, J P, Claycomb, W C

“…Rat ventricular cardiac muscle has previously been shown to contain exceptionally high levels of preproenkephalin mRNA (ppEnk mRNA). We have recently…”
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Cell-cell signaling between adult rat ventricular myocytes and cardiac microvascular endothelial cells in heterotypic primary culture by NISHIDA, M, SPRINGHORN, J. P, KELLY, R. A, SMITH, T. W

“…It is unclear whether signaling between endothelial cells and muscle cells within ventricular myocardium, known to be important during cardiac development,…”
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Preproenkephalin mRNA expression in developing rat heart and in cultured ventricular cardiac muscle cells by Springhorn, J P, Claycomb, W C

“…Heart muscle tissue has previously been reported to have the highest content of preproenkephalin (ppEnk) mRNA of any tissue in the adult rat. We have…”
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Posttranscriptional regulation of Id1 activity in cardiac muscle. Alternative splicing of novel Id1 transcript permits homodimerization by SPRINGHORN, J. P, KRISHNA SINGH, KELLY, R. A, SMITH, T. W

“…The transcriptional regulatory protein Id, a negatively trans-acting protein with a helix-loop-helix motif that is expressed in many proliferating tissues…”
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Role of Epicardial Mesothelial Cells in the Modification of Phenotype and Function of Adult Rat Ventricular Myocytes in Primary Coculture by Eid, Hoda, Larson, David M, Springhorn, Jeremy P, Attawia, Mohamed A, Nayak, Ramesh C, Smith, Thomas W, Kelly, Ralph A

“…Adult rat ventricular myocytes undergo a well-documented sequence of phenotypic changes during adaptation to primary culture. However, we observed that…”
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Monoclonal antibodies directed against human C5 and C8 block complement-mediated damage of xenogeneic cells and organs by Rollins, S A, Matis, L A, Springhorn, J P, Setter, E, Wolff, D W

“…The hyperacute rejection (HAR) of xenotransplanted organs is initiated by the deposition of natural antibodies on donor endothelium followed by the activation…”
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Role of plasminogen activator inhibitor in the reciprocal regulation of bovine aortic endothelial and smooth muscle cell migration by TGF-beta 1 by Petzelbauer, E, Springhorn, JP, Tucker, AM, Madri, JA

“…Vascular endothelial and smooth muscle cells exhibit reciprocal migratory responses after transforming growth factor (TGF)-beta 1 treatment. Endothelial cells…”
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Transcriptional regulation in cardiac muscle. Coordinate expression of Id with a neonatal phenotype during development and following a hypertrophic stimulus in adult rat ventricular myocytes in vitro by Springhorn, J P, Ellingsen, O, Berger, H J, Kelly, R A, Smith, T W

“…The transcriptional regulatory mechanisms in heart muscle that direct cardiac development and allow for a flexible, adaptive response to physiologic stress are…”
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Human Capillary Endothelial Cells from Abdominal Wall Adipose Tissue: Isolation Using an Anti-Pecam Antibody by Jeremy P. Springhorn, Madri, Joseph A., Squinto, Stephen P.

“…We have developed a novel isolation technique for harvesting human capillary endothelial cells. We compared the use of either Ulex Europaeus Agglutinin (UEA)…”
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Injectable retroviral particles for human gene therapy by Squinto, Stephen P., Rollins, Scott A., Springhorn, Jeremy P., Fodor, William L., Rother, Russell P.

“…The use of retroviral-mediated gene transfer as an in vivo approach for the treatment of human disease has been limited by the inability of retroviral vectors…”
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Role of plasminogen activator inhibitor in the reciprocal regulation of bovine aortic endothelial and smooth muscle cell migration by TGF-β1 by PETZELBAUER, E, SPRINGHORN, J. P, TUCKER, A. M, MADRI, J. A

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