Search Results - "Springer, D. L"

Observation of a small oligonucleotide duplex by electrospray ionization mass spectrometry by Light-Wahl, K. J, Springer, D. L, Winger, B. E, Edmonds, C. G, Camp, D. G, Thrall, B. D, Smith, R. D

“…Electrospray ionization (ESI) has been demonstrated to be a "soft" ionization technique, allowing accurate molecular weight determination for biopolymers due…”
Get full text

The PPAR-Platelet Connection: Modulators of Inflammation and Potential Cardiovascular Effects by Phipps, Richard P., Taubman, M. B., Blumberg, Neil, Springer, D. L., Lehmann, Geniece M., Bancos, S., O'Brien, J. J., Spinelli, S. L., Francis, C. W.

“…Historically, platelets were viewed as simple anucleate cells responsible for initiating thrombosis and maintaining hemostasis, but clearly they are also key…”
Get full text

COMPARATIVE METABOLISM OF CARBON TETRACHLORIDE IN RATS, MICE, AND HAMSTERS USING GAS UPTAKE AND PBPK MODELING by Thrall, K D, Vucelick, M E, Gies, R A, Zangar, R C, Weitz, K K, Poet, T S, Springer, D L, Grant, D M, Benson, J M

“…No study has comprehensively compared the rate of metabolism of carbon tetrachloride (CCl 4 ) across species. Therefore, the in vivo metabolism of CCl 4 was…”
Get full text

Characterization of Medium Conditioned by Irradiated Cells Using Proteome-Wide, High-Throughput Mass Spectrometry by Springer, D. L., Ahram, M., Adkins, J. N., Kathmann, L. E., Miller, J. H.

“…Springer, D. L., Ahram, M., Adkins, J. N., Kathmann, L. E. and Miller, J. H. Characterization of Medium Conditioned by Irradiated Cells Using Proteome-Wide,…”
Get full text

Enterohepatic recirculation of trichloroethanol glucuronide as a significant source of trichloroacetic acid : Metabolites of trichloroethylene by STENNER, R. D, MERDINK, J. L, STEVENS, D. K, SPRINGER, D. L, BULL, R. J

“…Trichloroacetic acid (TCA) is a metabolite of trichloroethylene (TRI) thought to contribute to its hepatocarcinogenic effects in mice. Recent studies have…”
Get full text

Uptake, Tissue Distribution, and Fate of Inhaled Carbon Tetrachloride: Comparison of Rat, Mouse, and Hamster by Benson, J M, Tibbetts, B M, Thrall, K D, Springer, D L

“…Carbon tetrachloride is hepatotoxic in rats, mice, and hamsters. However, rats are less sensitive to the hepatotoxic effects of CCl4 than the other two…”
Get full text

Profiling Mitochondrial Proteins in Radiation-Induced Genome-Unstable Cell Lines with Persistent Oxidative Stress by Mass Spectrometry by Miller, J. H., Jin, S., Morgan, W. F., Yang, A., Wan, Y., Aypar, U., Peters, J. S., Springer, D. L.

“…Miller, J. H., Jin, S., Morgan, W. F., Yang, A., Wan, Y., Aypar, U., Peters, J. S. and Springer D. L. Profiling Mitochondrial Proteins in Radiation-Induced…”
Get full text

Exploiting the special structure of conflict and compatibility graphs in high-level synthesis by Springer, D.L., Thomas, D.E.

“…Coloring of conflict graphs and clique partitioning of compatibility graphs have been used in high-level synthesis to map operators, values, and data transfers…”
Get full text

High-level expression of human histone H4 in E. coli by Burnett, V L, Springer, D L

Get full text

Characterization of Radiation-Induced Thymine-Tyrosine Crosslinks by Electrospray Ionization Mass Spectrometry by Mary S. Weir Lipton, Fuciarelli, Alfred F., Springer, David L., Edmonds, Charles G.

“…Exposure to ionizing radiation leads to formation of covalent crosslinks between DNA and proteins. The nature, extent and site of the modifications are not…”
Get full text

Dynamic and Differential in Vivo Modifications of the Isoform HMGA1a and HMGA1b Chromatin Proteins by Edberg, Dale D., Adkins, Joshua N., Springer, David L., Reeves, Raymond

“…Most naturally occurring mammalian cancers and immortalized tissue culture cell lines share a common characteristic, the overexpression of full-length HMGA1…”
Get full text

Influences of complex organic mixtures on tumor-initiating activity, DNA binding and adducts of benzo[a]pyrene by Springer, D L, Mann, D B, Dankovic, D A, Thomas, B L, Wright, C W, Mahlum, D D

“…Co-incubation of benzo[a]pyrene (BaP) and coal-derived complex organic mixtures has been shown to decrease the metabolism and mutagenic activity of BaP…”
Get more information

Cytochrome P450 2E1 is the primary enzyme responsible for low-dose carbon tetrachloride metabolism in human liver microsomes by Zangar, Richard C, Benson, Janet M, Burnett, Vicki L, Springer, David L

“…We examined which human CYP450 forms contribute to carbon tetrachloride (CCl 4) bioactivation using hepatic microsomes, heterologously expressed enzymes,…”
Get full text

Electrospray ionization mass spectrometric characterization of acrylamide adducts to hemoglobin by Springer, D L, Bull, R J, Goheen, S C, Sylvester, D M, Edmonds, C G

“…The most common procedure to identify hemoglobin adducts has been to cleave the adducts from the protein and characterize the adducting species, by, for…”
Get more information

Dichloroacetic acid and trichloroacetic acid-induced DNA strand breaks are independent of peroxisome proliferation by Nelson, M A, Lansing, A J, Sanchez, I M, Bull, R J, Springer, D L

“…This study examined whether the induction of single strand breaks in hepatic DNA by dichloroacetic acid (DCA) and trichloroacetic acid (TCA) depends upon…”
Get more information

Changes in adult metabolism of aflatoxin B1 in rats neonatally exposed to diethylstilbestrol. Alterations in alpha-class glutathione S-transferases by Zangar, R C, Springer, D L, McCrary, J A, Novak, R F, Primiano, T, Buhler, D R

“…Neonatal exposure of rats to xenobiotics has been shown to produce long-term alterations in hepatic enzyme activities and in levels of DNA adducts following…”
Get more information

Determination of polycyclic aromatic amines in skin by liquid chromatography with electrochemical detection by Felice, L J, Schirmer, R E, Springer, D L, Veverka, C V

Get more information

Evaluation of histone sequence and modifications by electrospray ionization mass spectrometry and tandem mass spectrometry by Edmonds, C G, Loo, J A, Smith, R D, Fuciarelli, A F, Thrall, B D, Morris, J E, Springer, D L

Get more information

DNA Damage can Alter the Stability of Nucleosomes: Effects are Dependent on Damage Type by Mann, David B., Springer, David L., Smerdon, Michael J.

“…We have investigated the effects of DNA damage by (± )-anti-benzo [a]pyrene diol epoxide (BPDE) and UV light on the formation of a positioned nucleosome in the…”
Get full text

Neonatal exposure to xenobiotics alters adult hepatic protein kinase C alpha levels and testosterone metabolism: differential effects by diethylstilbestrol and phenobarbital by Zangar, R C, Buhler, D R, Springer, D L

“…Hepatic enzymes that metabolize endogenous and xenobiotic compounds have been shown to be altered in adult rats that had been exposed to xenobiotics as…”
Get more information