Search Results - "Springate, James E."

Renal late effects in patients treated for cancer in childhood: A report from the Children's Oncology Group by Jones, Deborah P., Spunt, Sheri L., Green, Daniel, Springate, James E.

“…Improvements in childhood cancer therapy have led to increasing numbers of long‐term survivors. These survivors are at risk for a variety of late effects due…”
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Reduced phosphate transport in the renal proximal tubule cells in cystinosis is due to decreased expression of transporters rather than an energy defect by Taub, Mary L., Springate, James E., Cutuli, Facundo

“…► We examine the effect of a cystinosin knockdown. ► A cystinosin knockdown results in decrease phosphate transport and cellular ATP. ► Decreased phosphate…”
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Targeting of renal proximal tubule Na,K-ATPase by salt-inducible kinase by Taub, Mary, Springate, James E., Cutuli, Facundo

“…The renal proximal tubule (RPT) is a central locale for Na + reabsorption, and blood pressure regulation. Na + reabsorption in the RPT depends upon the…”
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Renal injury from valproic acid: case report and literature review by Zaki, Emad L, Springate, James E

“…A child with developmental delay and epilepsy developed glucosuria approximately 16 months after starting valproic acid therapy. Laboratory evaluation revealed…”
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Regulation of renal proximal tubule Na-K-ATPase by prostaglandins by Herman, Maryann B, Rajkhowa, Trivikram, Cutuli, Facundo, Springate, James E, Taub, Mary

“…Prostaglandins (PGs) play a number of roles in the kidney, including regulation of salt and water reabsorption. In this report, evidence was obtained for…”
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A mitochondrial DNA deletion presenting with corneal clouding and severe Fanconi syndrome by Lee, Joyce J., Tripi, Laura M., Erbe, Richard W., Garimella-Krovi, Sudha, Springate, James E.

“…Background Mitochondrial cytopathies are a diverse group of disorders characterized by impaired mitochondrial energy production. Disease manifestations are…”
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Lithium-induced membranous glomerulonephropathy in a pediatric patient by Kala, Gunjeet K., Mogri, Muniza, Weber-Shrikant, Edit, Springate, James E.

“…Lithium-induced glomerular toxicity is an infrequent occurrence in pediatric patients. We report a 13-year-old patient presenting with clinical and laboratory…”
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Interstitial nephritis from mesalazine: case report and literature review by Arend, Lois J, Springate, James E

“…We report a new case of biopsy-confirmed mesalazine-induced interstitial nephritis in an 18-year-old male with ulcerative colitis. His renal function improved…”
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Effect of nitric oxide inhibition on blood pressure and renal function in TGR(mRen2)27 rats by OZHAN DEDEOGLU, I, SPRINGATE, J. E

“…We examined the effect of acute systemic blockade of nitric oxide synthesis on blood pressure and renal function in the monogenetically hypertensive…”
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Comparative toxicity of ifosfamide metabolites and protective effect of mesna and amifostine in cultured renal tubule cells by Zaki, Emad L., Springate, James E., Taub, Mary

“…Renal injury is a common side effect of the chemotherapeutic agent ifosfamide. Current evidence suggests that the ifosfamide metabolite chloroacetaldehyde…”
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Effect of glutathione depletion on Ifosfamide nephrotoxicity in rats by Garimella-Krovi, Sudha, Springate, James E

“…Kidney injury is an important side effect of the chemotherapeutic agent ifosfamide in humans. Previous studies have shown that treatment with ifosfamide…”
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Additional causes of hypercalcemia in infants by Springate, James E

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Clinical and Biochemical Similarities Between Reflux/Obstructive Uropathy and Salt-Wasting Congenital Adrenal Hyperplasia by Mastrandrea, Lucy D., Martin, David J., Springate, James E.

“…Urinary tract obstruction and reflux nephropathy can be associated with changes in renal handling of water and electrolytes, leading to hyperkalemia, and…”
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Screening Dipstick Urinalysis: A Time to Change by Kaplan, Robert E, Springate, James E, Feld, Leonard G

“…This study attempted to determine the minimal cost of screening dipstick urinalyses in a hypothetical cohort of 2000 asymptomatic pediatric patients in a…”
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Oxybutynin does not affect cyclosporin blood levels by SPRINGATE, James E

“…Cyclosporin is an important immunosuppressive medication used to prevent organ rejection. Drug interactions that alter its blood levels can cause serious…”
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Enalapril and Renal Function in Hypertensive Rats Transgenic for Mouse Renin Gene by Springate, James E, Feld, Leonard G, Ganten, Detlev

“…We examined the effect of long-term enalapril treatment on renal function and histology in the monogenetically hypertensive TGR(mRen2)27 rat strain. Untreated…”
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Knockdown of Lysosomal Cystine Transporter Causes the Fanconi Syndrome in Primary Renal Cells by Taub, Mary, Springate, James E, Cutuli, Facundo

“…The autosomal recessive disorder cystinosis is due to a defect in cystinosin, a lysosomal cystine transporter. The Fanconi Syndrome emerges in the kidney in…”
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Regulation of Transcription of Renal Proximal Tubule Na,K‐ATPase by G‐Protein Coupled Receptors by Taub, Mary, Springate, James E, Khrovi, Sudha

“…Abstract only…”
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Hepatitis B vaccination of immunosuppressed children by West, D J

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Prophylactic antibiotics for immunocompromised children undergoing dental procedures by Hopkins, K P

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